惊厥

Objective To study the effect of treating infantile convulsion with phenobarbital combined with diazepam.

目的 探讨苯巴比妥联合地西泮治疗小儿惊厥的效果。

Treating infantile convulsion with phenobarbital combined with diazepam has better effect and is worth clinical studying and applying further.

苯巴比妥联合地西泮治疗小儿惊厥效果较好，值得临床进一步研究及应用。

Phenothiazine compounds should not be used in patients receiving large doses of hypnotics, should be used, with caution in patients with a history of convulssive disorders, since grand mal convulsions have been known to occur.

接受大剂量安眠药的患者不应使用吩噻嗪化合物，对有惊厥病史的患者应慎用，因为8 Tt t 8。 com 已知有发生过癫痫大发作。

Phenothiazine compounds should not be used in patients receiving large doses of hypnotics, and should be used, with caution in patients with a history of convulsive disorders, since grand mal convulsions have been known to occur.

接受大剂量安眠药的患者不应使用吩噻嗪化合物，对有惊厥病史的患者应慎用，因为已知有发生过癫痫大发作。

Phenothiazine compounds should not be used in patients receiving large doses of hypnotics, and should be used, with caution in patients with a history of convulssive disorders, since grand mal convulsions have been known to occur.65i

接受大剂量安眠药的患者不应使用吩噻嗪化合物，对有惊厥病史的患者应慎用，因为已知有发生过癫痫大发作。65i

METHODS: SC lasting for 30 minutes or 3 hours was induced by intraperitoneal injection of lithium chloride and pilocarpine.

采用氯化锂-匹罗卡品法诱发幼年Wistar大鼠SC发作，分别制备惊厥持续发作30 min和3 h的SC模型。

Seizures were induced in twenty-five adult rats with lithium and pilocarpine injected intraperitoneally.

选用成年Wistar鼠25只，经腹腔注射氯化锂和匹罗卡品，诱发大鼠惊厥发作。

Continuous epilepticus was induced by injecting lithium chloride and pilocarpine, and group C were daily injected with 100 mg/kg PDTC 30 minutes after convulsion stopped for 3 days.

匹罗卡品法制作大鼠SE模型，C组在大鼠惊厥终止后30 min，给予100 mg/kg PDTC腹腔注射，每天1次，连用3 d。

Result: 1、Ethology result:50 rats were injecting convulsive dose kainic acid, showing prodrome such as gaze, wet dog shake in the 0-30 minutes; 1-5 degree epileptic attack in the 30-60minutes; 4-5 degree repteately spontaneous epileptic attack in 60-90 minutes; then status epilepticus,SE-epileptic attack endurance became longer and interval became shorter with bulk salivas and various kinds psychomotor symptoms.

结果：1、行为学结果：SD大鼠(n=50)在注射惊厥剂量(10mg/kg)KA后，0-30min内动物出现凝视，湿狗样抖动(wet dog shake，WDS)等前驱症状；30-60min内动物出现1-5级癫痫发作；60-90min内动物反复自发出现4-5级癫痫发作；其后动物癫痫发作持续时间延长，间隔变短伴有大量唾液分泌，出现各种精神运动症状，呈现SE，SE后10天，用阈下剂量(5mg/kg)KA检测动物对癫痫刺激的敏感性。

Objective To explore the effect of Znic Protoporphyrin and its mechanism on the hemeoxygenase -1 (HO-1) mRNA expression in brain tissue of developing rat with febrile convulsion.

目的 探讨锌原卟啉对高热惊厥发育期大鼠血红素氧合酶-1 mRNA表达的影响及作用机制。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。