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We believe that CKLFSF8 is localized in early endosome, endosome recycling compartment and multivescular bodies in view of the colocalization between CKLFSF8 and LAMP1, a marker for late endosome and lysosome.

结合CKLFSF8与LAMP1的共定位情况,可以认为CKLFSF8定位于早期内体、内体循环小室和多胞体内。

Normally quiescent mature ependymal cells appear to revert to an embryonic state in response to spinal cord injury.

正常情况下静止的室管膜细胞在脊髓损伤后表现出胚胎期原始细胞的增殖状态。

Methods MRI findings of 26 cases with pathologically-proved PCNSL were analyzed retrospectively and the study emphasized on the location, signal feature, contrast-enhanced type, perilesional edema, ependymal seeding, and infiltration of corpus callosum.

回顾性分析26例术前行MRI检查并经病理证实的原发性中枢神经系统淋巴瘤资料,主要研究PCNSL的发生部位、信号特征、强化方式、瘤周水肿、室管膜播散以及胼胝体累及情况。

Department of Neonate,the Second Xiangya Hospital,Central South University,Changsha 410011,ChinaAbstract : Objective To study the incidence of extrauterine growth restrictionon premature neonates in NICU, to investigate the factors correlating with EUGR.

研究新生儿重症监护室中早产儿宫外生长发育迟缓的发生情况,探讨与早产儿EUGR有关的因素,为早产儿制定更为合理的营养支持策略提供指导。

Zeng lived a simple life on a small salary, often having to borrow money from the wealthier Hunanese in the capital to pay for the expenses of his own household and to ensure the adequate education of his younger brothers.

曾国藩的薪饷微薄,生活拮据,往往必须向京城内的同乡富室举债,才足以支付家用与诸弟的教育经费,一直到他奉派前往四川任乡试正考官之后,经济情况才告好转:一些望子成龙的家庭经常孝敬曾国藩,他才有能力还清债务。

Methods: The motion of parasternal papillary muscle anterior wall, inferior wall, posterior wall, and lateral wall were detected by 2DE at short axis view of left ventricle before PTCA, 3 d and 1-3 months after PTCA in 33 cases of patients with coronary heart disease, who received PTCA+stent at selected time. Peak systolic velocity of subendocardial, subepicardial and middle layer myocardium, transmural velocity difference of the same segments and Outer lateral mitral valve annulus were also detected at apical 4 chamber view by pulsed wave tissue Doppler imaging.

对33例择期行PTCA+支架术的冠心病患者用HP5500型超声诊断仪,于PTCA术前及术后3d、1-3个月对胸骨旁左心室乳头肌短轴切面的前间壁、下壁、后壁、侧壁行二维超声心动图(2DE)检测各节段的室壁运动情况,用脉冲组织多普勒成像检测上述各节段的内、外膜下及中层心肌的收缩期峰值速度,内外膜下心肌的收缩速度差及心尖四腔观二尖瓣外侧环的收缩期峰值速度。

The breeder is uniform forbid to string together, should stand fast working station, everyday perambulatory chicken group, sick, dead chicken should be chosen in time, discover unusual situation, answer to inform vet room instantly.

4,饲养员一律不准串栋,要坚守工作岗位,天天巡视鸡群,有病、死鸡要及时拣出,发现异常情况,应立即通知兽医室。

objective trimetazidine has shown anti-ischemic properties to improve exercise tolerance without haemodynamic effects and direct cyto protective effect on the myocardium.however,it is not clear whether trimetazidine has beneficially effect on severe ischemic cardiomyopathy.methods 19patients(68±9)years with postnecrotic left ventricular dysfunction(ejection fraction31.7%±5.4%)were studied to examine the benefit of adding60mg a day of trimetazidine for3months to the classical therapy.the assessment included clinical evaluation,electrocardiography and echocardiography.results after adding60mg a day of trimetazidine for3months,attack of angina was relieved and dyspnea was improved(p.05).but heart rate,systolic blood pressure,rate pressure product,ejection fraction,left ventricular volume and global wall motion index were not changed.conclusion trimetazidine seems to improve clinical status while can not change oxygen supply-to-demand ratio without adverse effects in patients on severe ischemic carˉdiomyopathy.

目的 曲美他嗪是一种新型的抗心肌缺血的药物,能够改善患者的运动耐量和心肌的直接保护作用同时并没有血流动力学效应。但目前对于严重缺血性心肌病患者的临床治疗价值还需要进一步观察。方法 19例(68±9)岁确诊为缺血性心肌病(左心室射血分数0%)的患者在常规治疗的基础上加用每日60mg曲美他嗪治疗3个月,随诊观察患者临床情况以及超声心动图指标的变化。结果 19例患者均可耐受在常规治疗基础上加用每日60mg曲美他嗪的治疗,随诊发现患者心绞痛发作明显减少,运动耐量明显改善。同时患者心率、收缩压、心率血压乘积、左心室射血分数、左心室容量以及整体室壁运动指数无明显改变。结论缺血性心肌病的患者在常规治疗基础上加用曲美他嗪是安全的,同时其能明显改善患者的临床状态,而这种作用并不改变心肌氧的供求比值。

AMs that collected, pured and cultured with contine method were stimulated by LPS of different concentration(0μg/ml,0.01μg/ml,0.1μg/ml,1μg/ml,10μg/ml) for 60min or by 1μg/ml LPS for different time stage (0min,5min,15min,30min,60min,120min) to observe the dynamic change of NF-кB intranuclear level and NO production, from which the best concentration and time point of LPS stimulation were selected. In the study, all AMs were divided into 4 groups: control group, group stimulated with LPS, group interrupted by Cal C and group inhibited by PDTC. The following parameters were measured: NF-кB level in nuclear protein extraction of AMs detected with sandwich ELISA, Inter-nuclear transposition of NF-кB observed with immunocytochemistry staining, NO content in cell culture medium quantitied with nitric acid reductase assay, Morphologic change of AMs in apoptosis observed with acridine orange staining and fragmentation at genome DNA of AMs detected with apoptotic electrophoresis assay.

分离、纯化及培养大鼠肺巨噬细胞;以不同浓度的LPS(0μg/ml,0.01μg/ml,0.1μg/ml,1μg/ml,10μg/ml)和不同作用时间(0min,5min,15min,30min,60min,120min)分别刺激小室培养的细胞单层,观察NF-κB的核内浓度及NO合成量的动态变化,选择LPS的最佳用量和作用时间;然后分成四组实验,设正常对照组,LPS处理组,特异性PKC抑制剂阻断组,NF-κB抑制剂阻断组;收集培养的单层细胞及培养液;采用夹心ELISA法定量测定细胞核提取物中的NF-κB水平;免疫组化法检测NF-κB的核内移位变化;硝酸还原酶法测定细胞培养液中NO含量;吖啶橙染色观察凋亡细胞的形态学变化,凋亡电泳实验检测细胞凋亡后基因组DNA的断裂情况。

PET has low spatial resolution which ca not distinguish transmural necrosis from subendocardial necrosis and can't demonstrate wall motion of left ventricular directly.

心肌PET显像空间分辨率低,无法显示心肌梗死的透壁程度,且不能直观显示室壁运动情况。

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Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时,他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

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The enrich the peopling of Deng Xiaoping of century great person thought, it is the main component in system of theory of Deng Xiaoping economy, it is a when our country economy builds basic task important facet.

世纪伟人邓小平的富民思想,是邓小平经济理论体系中的重要组成部分,是我国经济建设根本任务的一个重要方面。