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Results Women were more often affected than men(1.83:1) and 53 patients were older than 40 years. The involved parts were as follows: eyelid 58 cases (89.2%), mouth and mandibula 46 cases(70.8%),neck 17 cases(26.2%). The symptom at onset were blepharospasm 42 cases(64.6%) or oromandibular dystonia 17 cases(26.2%).In part of the patients, cranial MRI examination could find focus in brainstem or basal ganglia. Among 37 patients treated with oral drugs, 4 cases were almost cured, 16 cases improved and 17 cases showed no effect. While in 15 patients treated through chiostridium botulinum toxin injection, 5 were almost cured, 9 improved and 1 had no effect.

结果 男女患病比率 1:1.83,40岁以上发病53例,受累部位依次为眼睑58例(89.2%)、口-下颌46例(70.8%)、颈部17例(26.2%);首发症状以眼部不适、眼睑痉挛最(42例,占64.6%),口-下颌肌张力障碍次之(17例,占26.2%);14例行头MRI检查者8例发现脑干或基底节区病灶;口服药物治疗37例,显效4例,有效16例,无效17例;15例行肉毒毒素局部注射者显效5例,有效9例,无效1例。

The symptom at onset were blepharospasm 42 cases(64.6%) or oromandibular dystonia 17 cases(26.2%).in part of the patients, cranial mri examination could find focus in brainstem or basal ganglia. among 37 patients treated with oral drugs, 4 cases were almost cured, 16 cases improved and 17 cases showed no effect. while in 15 patients treated through chiostridium botulinum toxin injection, 5 were almost cured, 9 improved and 1 had no effect.

结果 男女患病比率为1:1.83,40岁以上发病53例,受累部位依次为眼睑58例(89.2%)、口-下颌46例(70.8%)、颈部17例(26.2%);首发症状以眼部不适、眼睑痉挛最多(42例,占64.6%),口-下颌肌张力障碍次之(17例,占26.2%);14例行头mri检查者8例发现脑干或基底节区病灶;口服药物治疗37例,显效4例,有效16例,无效17例;15例行肉毒毒素局部注射者显效5例,有效9例,无效1例。

RESULTS: These familial keloids mainly occurred during adolescence, showing the equal chance of being affected between male and female subjects. The affected person could be heterozygous, and a child of an affected parent had a 50% chance of being affected. Thirteen subjects displayed familiar keloid, 1 suspected keloid, 2 did not present keloid as obligate carriers, and 1 did not present keloid as doubtful carrier. One pedigree displayed keloid in 3 generations, two displayed in 2 generations. The traits of familial keloids were transmitted interruptedly, revealing incomplete penetrance. The clinical phenotypes of familial keloids presented variable expression among the different affected.

结果:这些瘢痕疙瘩家系以青春期发病为主,男女患病的机会均等;杂合体即可发病,双亲之一发病其半数子女可能发病;3个瘢痕疙瘩家系发病13人,可疑发病1人,2个未发病肯定携带者,1个未发病可疑携带者;3代发病家系1个,2代发病家系2个;瘢痕疙瘩性状存在间断传递、外显不完全现象;临床表型存在个体差异。

But there is no difference between 2007 detectable rate and 2006 detectable rate(P>0.05).Conclusion The health of people who was examined has disease in 2006 was no melioration in 2007,even some was aggravated.This indicate the system of follow-up survey and health education are incomplete,which need us take measures to improve it.

2006年体检出现健康问题的体检者,年后再次体检发现健康状况并没有改善,并且部分人还有加重的趋向,虽然随年龄的增长患病的可能性会增加,但也说明体检后的跟踪随访和健康教育做得不够好,需要进一步改善。

In addition, the Evening News reported that experts warned that the prevalence of diabetes has been much earlier age, 30 to 40-year-old man,"potbellied" those most vulnerable to disease.

此外,新闻晚报报导,专家警告,糖尿病患病年龄已大大提前,30至40岁男性「大腹便便」者最易患病。

At conception, each sib of an affected individual has a 25% chance of being affected, a 50% chance of being an asymptomatic carrier, and a 25% chance of being unaffected and not a carrier.

理论上,每个患者的兄弟姐妹有25%的几率患病,有50%的几率是没有症状的携带者和25%的几率是不患病的非携带者。

Results Women were more often affected than men(1.83:1) and 53 patients were older than 40 years. The involved parts were as follows: eyelid 58 cases (89.2%), mouth and mandibula 46 cases(70.8%),neck 17 cases(26.2%). The symptom at onset were blepharospasm 42 cases(64.6%) or oromandibular dystonia 17 cases(26.2%).In part of the patients, cranial MRI examination could find focus in brainstem or basal ganglia. Among 37 patients treated with oral drugs, 4 cases were almost cured, 16 cases improved and 17 cases showed no effect. While in 15 patients treated through chiostridium botulinum toxin injection, 5 were almost cured, 9 improved and 1 had no effect.

结果 男女患病比率为1:1.83,40岁以上发病53例,受累部位依次为眼睑58例(89.2%)、口-下颌46例(70.8%)、颈部17例(26.2%);首发症状以眼部不适、眼睑痉挛最多(42例,占64.6%),口-下颌肌张力障碍次之(17例,占26.2%);14例行头MRI检查者8例发现脑干或基底节区病灶;口服药物治疗37例,显效4例,有效16例,无效17例;15例行肉毒毒素局部注射者显效5例,有效9例,无效1例。

The involved parts were as follows: eyelid 58 cases (89.2%), mouth and mandibula 46 cases(70.8%),neck 17 cases(26.2%). The symptom at onset were blepharospasm 42 cases(64.6%) or oromandibular dystonia 17 cases(26.2%).In part of the patients, cranial MRI examination could find focus in brainstem or basal ganglia. Among 37 patients treated with oral drugs, 4 cases were almost cured, 16 cases improved and 17 cases showed no effect. While in 15 patients treated through chiostridium botulinum toxin injection, 5 were almost cured, 9 improved and 1 had no effect.

结果 男女患病比率为1:1.83,40岁以上发病53例,受累部位依次为眼睑58例(89.2%)、口-下颌46例(70.8%)、颈部17例(26.2%);首发症状以眼部不适、眼睑痉挛最多(42例,占64.6%),口-下颌肌张力障碍次之(17例,占26.2%);14例行头MRI检查者8例发现脑干或基底节区病灶;口服药物治疗37例,显效4例,有效16例,无效17例;15例行肉毒毒素局部注射者显效5例,有效9例,无效1例。

Subjects with plasma Aβ42/Aβ40 ratios in the lower quartiles showed significantly greater risk of MCI orAD(P=.04, adjusted for age and apolipoprotein E genotype).

血浆Aβ42/Aβ40比值在下四分位数者,MCI或AD的患病风险明显增高(P=0.04,按年龄和载脂蛋白E基因型进行校正)。

Results 17 patients reported in the literature had primary bronchogenic carcinoma with metastases of phalanges of fingers as its first symptom. 7 patients' metastatic lesions located in their phalanges of left hands, 9 right hands and 1 both hands. The distribution of the quantity of the phalangeal metastases between two hands was almost equal. 3 patients' metastatic lesions were situated in proximal phalanges of fingers, and the rest in distal. 6 patients' ill fingers had had trauma history.

结果 在文献报道的以单纯指骨转移为首发症状的17例原发性肺癌的病人中,其转移病灶位于左手指骨者7例,右手指骨者9例,双手指骨者1例,指骨转移病灶的数量在两手之间的分布大致相等,除3例病人其转移病灶位于近节指骨外,其余病人的转移病灶均位于其末节指骨;有6例病人的患病手指既往曾有外伤史。

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