患...病

In a prospective trial, they evaluated this hypothesis using serum samples obtained from 31 patients who underwent allogeneic transplantation using human leukocyte antigen-identical siblings as donors. All patients in the cohort received 1 to 3 pretransplant chemotherapy cycles to induce uniform host lymphopenia, which was followed by fludarabine-based reduced-intensity conditioning. Cyclosporine methotrexate was administered as prophylaxis against the development of GVHD.

在一项前瞻性研究中，他们透过测量31位接受异体移植血液干细胞移植病患血清来评估这项假设，这些病患都是接受人类白血球抗原比对相符同属作为捐赠者，他们都接受移植前化学治疗1至3个周期，以诱发宿主淋巴球数目低下，接著以fludarabine为主的低密度调节化学治疗，且投予cyclosporine与methotrexate用于预防GVHD的发生。

In a prospective trial, they evaluated this hypothesis using serum samples obtained from 31 patients who underwent allogeneic transplantation using human leukocyte antigen-identical siblings as donors. All patients in the cohort received 1 to 3 pretransplant chemotherapy cycles to induce uniform host lymphopenia, which was followed by fludarabine-based reduced-intensity conditioning. Cyclosporine methotrexate was administered as prophylaxis against the development of GVHD.

在一项前瞻性研究中，他们透过测量31位接受异体移植血液干细胞移植病患血清来评估这项假设，这些病患都是接受人类白血球抗原比对相符同属作为捐赠者，他们都接受移植前化学治疗1至3个周期，以诱发宿主淋巴球数目低下，接著以fludarabine为主的低密度调节化学治疗，且投予cyclosporine与methotrexate用於预防GVHD的发生。

Patients who received reduction mammaplasty for juvenile macromastia in NTUH from January 2003 to December 2005 are enrolled as macromastia group. The control group includes the patients who received breast operation for breast cancer in NTUH in the same time period, with breast sizes not larger than C cup.

我们搜集西元2003年至2005年因青春期巨乳症而至台大医院接受缩乳手术且乳房尺寸大於等於E罩杯的病患为巨乳组，对照组则选取同一时期因乳癌於台大医院接受乳房切除手术且乳房尺寸小於等於C罩杯的病患，选取其未受乳癌侵犯的乳房组织。

Despite the poor response rates in the chemotherapy-alone group, Dr. Burstein believes that metronomic chemotherapy combined with bevacizumab should be investigated further, given the tolerability of the agents and the preclinical rationale for efficacy. When asked why cyclophosphamide and methotrexate were selected for metronomic chemotherapy, he observed that many patients in this setting are already somewhat chemotherapy-resistant.

尽管只接受化学疗法的病患反应率很低，Burstein医师相信节律性化学疗法加上bevacizumab应该进一步研究，因为该药物的耐受性良好，而且临床前实验认为是有效的；当被问到为什么选择cyclophosphamide与methotrexate作为节律性化学疗法的药物，他观察发现，许多病患在这个时候已经对许多化学疗法产生抗药性。

Despite the poor response rates in the chemotherapy-alone group, Dr. Burstein believes that metronomic chemotherapy combined with bevacizumab should be investigated further, given the tolerability of the agents and the preclinical rationale for efficacy. When asked why cyclophosphamide and methotrexate were selected for metronomic chemotherapy, he observed that many patients in this setting are already somewhat chemotherapy-resistant.

尽管只接受化学疗法的病患反应率很低，Burstein医师相信节律性化学疗法加上bevacizumab应该进一步研究，因为该药物的耐受性良好，而且临床前实验认为是有效的；当被问到为什麼选择cyclophosphamide与methotrexate作为节律性化学疗法的药物，他观察发现，许多病患在这个时候已经对许多化学疗法产生抗药性。

All tests, including acoustic reflectometry, tympanometry, pneumatic otoscopy, and videotelescopy were performed in the two days preceding surgery. Myringotomy or tympanic aspiration was then performed to confirm the presence or absence of OME.

远距镜录影系统检查时病患可采坐姿或站姿，检查者将病患耳郭向后轻拉，再将远距镜经由外耳道放至鼓膜前，在监视器上取得清晰且放大影像。

FDA approval was based on data from a multicenter, double-blind, randomized clinical trial in which 72 patients received 1 of the 2 formulations in each nasolabial fold. Results showed that 93% of patients reported less procedural pain when treated with the lidocaine-containing dermal filler compared with the original version.

FDA的核准是根据一个多中心、双盲、随机临床试验，有72个病患在两侧的法令纹分别接受这两种配方之一；结果显示，93%的病患指出，使用含有lidocaine的皮肤注入器时，在疗程中比较少疼痛。

The December issue reports that stage 3 to 5 CKD is found in 4% to 5% of the adult population in the United Kingdom, most often in elderly individuals who have comorbidities for which they are prescribed several drugs. The authors remind practitioners that patients with impaired renal function have decreased drug clearance by the kidney and may be more susceptible to certain nephrotoxic drugs. They advise:"Whenever possible, should take steps to minimize these risks, by avoiding the drugs, using reduced doses or administrative frequency, or increasing the monitoring of renal function" by measuring estimated glomerular filtration rate.

12月号的报导刊载了英国人口中，有4%至5%是CKD第3至5级，大部分是老年人，且这些病患经常使用多种药物；作者提醒执业医疗人员，肾脏功能不全病患其肾脏排除药物的清除率下降，而且更可能受到某些具有肾毒性药物的伤害；他们建议，当情况允许时，执业人员应该将这些风险降到最低，透过避免使用部分药物，或是降低剂量、或频次，或是增加监测肾丝球廓清率的频率来评估肾脏功能。

Dr. Harrison pointed out that the concern about adherence has ramifications beyond schizophrenia."Approximately 20% to 30% of patients don't refill prescriptions of any type, whether they're antipsychotics or statins," he said. In schizophrenia, the investigators reported, the issue of nonadherence is more widespread and the consequences more dire: 40% to 50% of patients with schizophrenia do not adhere to their prescribed medications and are therefore at risk for exacerbation of psychosis and rehospitalization.

Harrison医师指出，关于服药顺从性的忧虑是精神分裂疾病的副产物，大约20%至30%的病患不会再回来领药，不论是何种形式的药物，抗精神分裂药物或是statins类药物；以精神分裂症来说，顺从性不佳的情况更是普遍，而且后果更是可怕，将近有40%至50%的精神分裂症病患并不会按时服药，因此是精神病发与住院的高危险群。

Dr. Harrison pointed out that the concern about adherence has ramifications beyond schizophrenia."Approximately 20% to 30% of patients don't refill prescriptions of any type, whether they're antipsychotics or statins," he said. In schizophrenia, the investigators reported, the issue of nonadherence is more widespread and the consequences more dire: 40% to 50% of patients with schizophrenia do not adhere to their prescribed medications and are therefore at risk for exacerbation of psychosis and rehospitalization.

Harrison医师指出，关於服药顺从性的忧虑是精神分裂疾病的副产物，大约20%至30%的病患不会再回来领药，不论是何种形式的药物，抗精神分裂药物或是statins类药物；以精神分裂症来说，顺从性不佳的情况更是普遍，而且后果更是可怕，将近有40%至50%的精神分裂症病患并不会按时服药，因此是精神病发与住院的高危险群。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。