息肉病

Objective To summarize the experience in diagnosis and therapy of familial adenomatous polyposis with desmoid tumour.

目的探讨家族性腺瘤性息肉病伴发硬纤维瘤的诊断和治疗。

Objective: To explore the characteristics of germline APC gene mutations in Chinese patients with familial adenomatous polyposis.

目的：探讨国人家族性腺瘤性息肉病患者APC基因胚系突变的特点。

As with familial adenomatous polyposis, the inheritance pattern is autosomal dominant.

家族性腺瘤息肉病的遗传方式是常染色体显性遗传。

Methods Clinical data of 6 patients with familial adenomatous polyposis and desmoid tumour from Jan 1989 to Jan 2005 were retrospectively analyzed.

方法回顾性分析1995年1月至2005年1月收治的6例家族性腺瘤性息肉病并发硬纤维瘤患者的手术史、临床表现、治疗方法和随访结果，分析总结诊疗经验。

Objective: To analyze the expression of cyclooxygenase-2(COX-2) in patients with familial adenomatous polyposis and to discuss the possible role of COX-2 in adenoma formation and cancerization.

目的：分析环氧化酶2(COX-2)在家族性腺瘤性息肉病中的表达，探讨COX-2在腺瘤形成以及癌变过程中的可能作用。

Abstract］ Objective To discuss the clinical observation and nursing care of the patients with familial adenomatous polyposis treated with herb medicine.

目的 探讨中药治疗家族性大肠息肉病的护理。

Since FAP was first known 120 years ago, knowledge about FAP as well as clinical diagnosis and treatment of the condition has been evolving gradually, from knowing it as multiple polyposis in early years to the establishment of sized familial registration centers in American and European countries today;from permanent colostomy in the past to widespread use of up-date pouches; and from finding association of FAP with apenteric lesions to the study of APC genotype-phenotype at molecular level.

文献报道FAP已有120多年，早期认为是多发性结肠息肉病到目前建立的规模性家系登记中心；从过去采用永久性的回肠造口治疗方式到当今保留肛门回肠贮袋与肛管吻合的术式；从发现FAP肠外病变到在分子水平开展APC基因型-表现型之间的研究，FAP的临床诊治水平在不断提高。

Adenomatous pelypesis, coli ; Colectomy; Pouch, intestinal ; Fibromatosis

腺瘤息肉病结肠结肠切除术回肠贮袋硬纤维瘤，侵袭性

Results Of 62 cases of PMLGI, 6 cases were low grade malignant B-cell lymphoma of MALT type, 14 cases high grade malignant B-cell lymphoma of MALT type with a low grade malignant component, 1 case lymphomatous polyposes, 2 cases Butkitt-like lymphoma, 38 cases B-cell large cell lymphoma and 1 case intestinal T-cell lymphoma.

结果：62例PMLGI中，低度恶性B细胞粘膜相关组织型淋巴瘤6例，高度恶性B细胞粘膜相关组织型淋巴瘤伴低恶成分14例，淋巴瘤性息肉病1例，Burkitt样淋巴瘤2例，B大细胞淋巴瘤38例，肠道T细胞淋巴瘤1例。

Methods 12 diagnosed patients of 2 HNPCC pedigrees were collected and followed up.

目的 探讨遗传性非息肉病性大肠癌家系的临床特征。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。