恙虫病

Objective:To obtain Rickettsia tsutsugamushi antibody levelin patients and healthy population of epidemic area and non-epidemic area, and to get the seroepidemiological pattern of tsutsugamushi disease in Hebei province based on serological typing and dynamic observation.

目的：对河北省恙虫病疫源地内病例进行血清学分型和抗体动态观察，了解疫源地和非疫源地内人群恙虫病抗体阳性率，初步掌握恙虫病血清流行病学规律。

Both 47- and 56-kDa proteins are considered as the major surface proteins of Ot, which has a potential importance in development of subunit vaccine against scrub typhus.

研究证明，这两种外膜蛋白均存在菌体表面并具有良好的免疫原性，已成为恙虫病东方体亚单位疫苗的重要候选分子。58kDa蛋白是恙虫病东方体的热休克蛋白，属于Hsp60家族。

Results scrub typhus complicated with hepatic lesions occurred to 73.5%(36/49) of patients, gastrointestinnal manifestations including nausea and vomit occurre to 33.3% of the patients (12/36,) and abdominal distention(21/36,58.3%).elevated serum alanine aminotransferase and aspartate aminotransferase were observed in allthe 36 cases. of which 9 cases(25.0%) had elevated serum total bilirubin,16 cases (44.4%) had elevated alkaline phosphatase and 14 cases (38.9%) had decreased serum albumin.

结果 36例恙虫病合并肝损害患者占同期恙虫病患者的73.5%，其中胃肠道症状有恶心呕吐12例，腹胀21例；36例患者血清alt及ast均升高，其中血清tbil升高9例，血清碱性磷酸酶升高16例，alb降低14例；b型超声检查肝脏肿大13例，脾脏肿大16例，有腹水者9例。

Macrolide antibiotics, such as chloramphenicol and deoxycycline, have good therapeutic effects on scrub typhus. Macrolide antibiotics also have fewer side-effects, and they are suitable for pregnant women, puerperant, and infants with scrub typhus. Azithromycin may be used as a first-line drug.

大环内酯类药物、氯霉素和强力霉素对恙虫病均有较好疗效，而大环内酯类抗生素副作用小，孕产妇、婴幼儿及肝肾功能受损等病人适用大环内酯类抗生素治疗恙虫病，其中阿齐霉素为首选。

Objective In order to detect the gene homologies of orientia tsutsugamushi isolated from scrub typhus patients,chigger mites,and rodents of Shandong province in epidemic season.

恙虫病是由媒介恙螨叮咬传入恙虫病东方体(Orientiatsutsugamushi，Ot)的急性传染病，其动物宿主鼠类居多，容易引起暴发流行。

Orientia tsutsugamushi; Scrub typhus; Rodents; Epidemiology,molecular

恙虫病东方体恙虫病啮齿动物流行病学，分子

Methods : Meta analysis was used for compiling, inducing and processing the data of tsutsugamushi disease and Ot published in the two provinces.

采用Meta分析法对两省发表的恙虫病和恙虫病东方体感染相关资料进行汇总、归纳和统计分析。

the incidence of the liver function injuries in patients with tsutsugamushi disease is common and the injury is associated with age of patients and death rate. thus effective measures be taken for enhancement of cure rate.

恙虫病患者并发肝脏损害较普遍，而且与患者的年龄及死亡率密切相关，因此，在恙虫病患者病程中动态监测肝功能变化有助于判断病情，及早作相应保护性治疗，可防止病情恶化，提高治愈率。

Methods The results of examination of liver function o 45 patients with tsutsugamushi disease were retrospectively analyzed. Results The incidence of liver injuries in patietns with tsutsugamushi disease was 64.8%（35/54）, being 40.7%, 16.7% and 7.4% in the mild, moderate and severe injury respectivelyly. The injury in senile patiens was markedly severe than that of young and middle age groups.

结果 恙虫病患者病程中肝功能损害的发生率 64.8%（35/54），轻、中、重度肝功能异常的发生率分别为40.7%、16.7%、7.4%，以轻度损害为主；老年组恙虫病较中青组肝功能损害严重，差异有显著性；死亡组肝功能损害程度显著高于存活组。

Results the incidence of liver injuries in patietns with tsutsugamushi disease was 64.8%（35/54）, being 40.7%, 16.7% and 7.4% in the mild, moderate and severe injury respectivelyly. the injury in senile patiens was markedly severe than that of young and middle age groups. the injury in dead was significantly servere than that of the survivors.

结果 恙虫病患者病程中肝功能损害的发生率为64.8%（35/54），轻、中、重度肝功能异常的发生率分别为40.7%、16.7%、7.4%，以轻度损害为主；老年组恙虫病较中青组肝功能损害严重，差异有显著性；死亡组肝功能损害程度显著高于存活组。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了