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恒河猴

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Here we show that sooty mangabeys have substantially reduced levels of innate immune system activation in vivo during acute and chronic SIV infection and that sooty mangabey plasmacytoid dendritic cells produce markedly less interferon- in response to SIV and other Toll-like receptor 7 and 9 ligands ex vivo.

首先,研究人员发现,与被感染的恒河猴相比,成熟和活化的pDCs(通过形成IFNα和引发适应的免疫响应而扮演了一个关键的抗病毒角色)在被感染的乌白眉猴中含量很低,其中pDCs并没有转移到被感染的乌白眉猴的淋巴结中。

Despite being able to SIV-infected monkeys in Ukraine Agkistrodon have a high level of viremia, but the virus does not lead to a large number of generalized immune activation, which is in the AIDS and SIV-infected rhesus monkeys as well as HIV Infection in the development of human characteristics.

尽管SIV能够在被感染的乌白眉猴中产生高水平的病毒血症,但这种病毒并不能导致大量普遍化的免疫激活,而这正是与AIDS在被SIV感染的恒河猴以及被HIV感染的人体中发展有关的特征。

In this study, we analyzed 8 rare and endangered animals, including giant panda, Yunnan golden monkey, red panda, Asiatic black bear, rhesus monkey, slow lorries, Chinese pangolin and concolor gibbons from China and adjacent areas.

本文以我国珍稀动物大熊猫、滇金丝猴、小熊猫,亚州黑熊、间蜂猴、恒河猴、中国穿山甲、黑冠长臂猿为材料,采用蛋白和同工酶电泳以及线粒体DNA序列分析(包扩采用非损伤取样以毛发和陈旧皮张样品进行的分析)的方法研究珍稀动物的遗传多样性状况及其同物种濒危的关系以及根据遗传学数据确定保护的基本单元等。

ABSTRACT:Objective To investigate the biological and clinical features of Chinese rhesus m onkey s after intravenous and intrarectal challenge with SIVmac239 in rhesus m onkey s of Chinese origin, and compare the differences between the routes of infection.

目的 研究猴免疫缺陷病毒SIVmac239毒株经静脉及直肠途径感染中国恒河猴后的生物学特性和症状表现,并比较由感染途径不同导致的差异,为该模型系统的应用提供依据。

Results It was able to analyze the DNA polymorphism using 15 polymorphic microsatellite loci between Macaca mulatta and Macaca irus. The allele numbers were more than 7, and there were differences in 11 allele numbers between the two groups.

结果 筛选的15个具有显著多态性的微卫星DNA位点对恒河猴和食蟹猴种群可以进行DNA多态性分析,其等位基因数目均在7个以上,且两群体间有11个位点的等位基因数存在一定的差异。

It will be feasible in setting up a genetic analysis method by using PCR-analyzed polymorphic microsatellite DNA loci between Macaca mulatta and Macaca irus.

利用这些多态性微卫星DNA位点建立一种有效鉴别恒河猴和食蟹猴种群遗传背景的方法具有一定的可行性。

Methods The DNA polymorphism was analyzed in 50 individuals of Macaca mulatta and 50 individuals of Macaca irus using 15 PCR-microsatellites DNA loci and the differences of allele numbers between those two species were compared.

利用聚合酶链反应扩增技术采用15个多态性微卫星DNA位点对50只恒河猴和50只食蟹猴个体进行了DNA多态性的分析,对比两群体间等位基因数目差异。

The mangabeys have been able to resist SIV, while the macaques, much like humans, inevitably succumb to it.

白眉猴已经能够抵抗猴免疫缺陷病毒,而恒河猴,就像人类一样,不可避免地屈从于它。

Research determined that the immune systems of primates like mangabeys are not activated to such a high extent as the immune systems of the macaques when SIV infection occurs.

研究表明,当猴免疫缺陷病毒传染发生,白眉猴的免疫系统被激活的程度没有恒河猴的那么高。

If modern man descended from primitive apes and if 85% of humans have the rhesus positive blood factor, was the remaining 15% of the rhesus negative blood factor inherited from Annunaki/human crossbreeding?

如果现代人类是原始大猩猩的后裔,85%的人类有恒河猴的阳性血液遗传因子,那剩下15%的恒河猴阴性的血液基因是从安鲁那奇人与人类杂交得来的吗?

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