总的

CaN Aβ gene silencing can reduce myocardial hypertrophy in cultured cells, si1280 (21bp) of CaN Aβ gene is the most effective target site for siRNA. The method of intrapericardial injection of plasmid, microbubbles and erzymes can improve transfection efficiency of non-viral plasmid with satisfying targeted transfection. But the scope of transfected myocytes is still limited. CaN Aβ shRNA expressing plasmid transfection in vivo by pericardial injection results in decreased CaN Aβ protein expression of small part of myocytes, and CaN Aβ mRNA only shows decreased trend. The dosage of non-viral vector and the parameters of ultrasound energy should be optimized in further study.

结论RNAi技术抑制CaN Aβ基因表达可有效减轻Ald诱导的心肌细胞肥大程度；CaN Aβ基因中si1280(21bp)片段为实现RNAi的更有效片段；微泡+酶类心包腔内注射超声导入的方法可有效改善非病毒载体在体心肌的转染效率，同时具有一定的靶向性，但总的转染范围仍然有限；采用这一方法进一步进行&一肾一夹&心肌肥大模型大鼠在体心肌细胞的CaNAβ的RNAi干预，发现心肌肥大大鼠心外膜下局部心肌细胞CaN Aβ蛋白水平降低，CaN AβmRNA水平虽有下降趋势，但无统计学差异，提示质粒的用量及超声导入的参数有待进一步研究使其优化。

The results showed that the kinetical rule of the ion-exchange reaction was not changed, the ion-exchange process was still controlled by the grain diffusion, and the concentration of Cl~- has little effect on the apparent activation energy of reaction if the total concentration of ion in the solution kept invariableness.

结果表明，在维持溶液中离子总的当量浓度不变的条件下，离子交换反应的动力学规律不会发生改变，反应仍然是受粒扩散控制，氯离子浓度对交换反应表观活化能的影响不大。

The work was closed with a general "Review and Conclusion", in direct response to the war which raised the question of the subject's right to change allegiance when a former sovereign's power to protect was irrecoverably gone.

这一著述以一个总的&评论和结论&结束，这是对前统治者丧失保护能力时引发的公民改变效忠权问题的战争的直接反应。

For all the nitrogen and kalium fertilization of wheat,the regression coefficients R2 are 0.710 4 and 0.853 4 respectively.

对于不同氮、钾处理的小麦，PRI和LUE之间都获得了很好的相关关系，总的相关系数R2分别是0.710 4和

In the Jurassic and Cretaceous, generally it was also the shelf sea, but there were lacustrine and lagoonal environments in different parts of the basin.

侏罗纪－白垩纪在总的浅海陆棚环境下，盆地不同地区也形成了湖泊和潟湖环境。

That is lowish, but Italy's public debt stands at 115%, second only to Greece in the euro area.

虽然这一比例并不高，但是意大利总的公共债务高达115%，在整个欧元区仅次于希腊。

The total inflation-adjusted reimbursed costs for lumbosacral injections increased from $24 million to oer $175 million.

总的腰骶注射通货膨胀调整花费从24，000，000美元增长到了超过175，000，000美元。

In adult acute lymphocytic leukemia complete remission rates of 70%-85% can be achieved.

目前成人急性淋巴细胞白血病总的完全缓解率为70—85％。

Prior to co-founding Neuma in 1990 and directing the development of CM+, Joe was Director of Software Architecture and Technology at Mitel, and in the 1970s a Development Manager at Nortel (Bell-Northern Research) where he developed the Program Library System still heavily in use by Nortel's largest projects.

事先协调neuma成立于1990年，导演等的发展公分+，是乔总的软件体系结构和技术为Mitel ，以及在1970年代开发经理北电网络，他开发出程序库系统，仍然在大量使用的北电的最大项目。

Unless since land it utilize by change watch, the with the fastest developing speed in cities and towns, the forest land , the whole area of herb ground increase very fast under the policy of grain for green, Yuan Tai station nonirrigated farmland increase by a large margin, the land of rivers and creeks is reducing, land use ratio of Jingchuan county remain to raise, the total area of use is reducing too.

从土地利用变化看，城镇的发展速度最快，林地、牧草地总面积在退耕还林还草的政策下增加较快，塬台旱地大幅度增加，河川地在减少，泾川县总的未利用面积在减少，而土地的利用率有待提高。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！