性细胞遗传的

In the progress of tumor development, it shows heterology, and formed different subgroup, promote metastasis.

其表现为肿瘤在组织形态学、核型，免疫表型，遗传标志物，生长率，细胞产物，药物敏感性以及其他细胞组织学特征方面呈现广泛的多态性，从而产生不同转移能力的癌细胞。

The basic principles of drug metabolism and its enzyme are discussed, with an emphases on the interindividual variations and ethnic differences of two monooxygenases (cytochrome P450 CYP2D6 and CYP2C19) and one conjugation enzyme (N-acetyltransferases).

综述近10年来国内外有关药物代谢酶的分子遗传学进展，介绍药物代谢酶的基本概念并重点探讨了具有遗传多态性的两种氧化酶（细胞色素P450酶 CYP2D6 ， CYP2C19）和一种结合酶的个体和种族差异。

Polymorphism of Rb (intron 17) is relatively stable and rarely mutates, but poly morphism of Rb gene (intron 20) locus is characteristic in the old people. The r elation between Rb gene (intron 20) and ageing needs further study.

老年组Rb基因20内含子的位点多态性与青年组比较差异有显著性意义，是否该位点遗传标记与细胞的衰老有一定的相关性，值得进一步研究。

Donor bacteria, through its pilus bacteria with receptors contact, the former transmission of different length single strand of DNA to the latter, and in the latter cells for double-stranded or further nuclear chromosome in exchange, integration, so that the latter was the donor of the genetic traits phenomenon.

供体菌通过其性菌毛与受体菌相接触，前者传递不同长度的单链DNA给后者，并在后者细胞中进行双链化或进一步与核染色体发生交换、整合，从而使后者获得供体菌的遗传性状的现象。

AIM: To determine the distribution and frequency of functionally important allelic variants in the cytochromes P450 2C19, arylamine N-acetyltransferase 2 (NAT2), and thiopurine S-methyltransferase genes in the Han Chinese population and compare them with those of other ethnic populations.

目的： 了解细胞色素P450(cytochromes P450，CYP)2C19，N-乙酰基转移酶2(arylamine N-acetyltransferase 2，NAT2)和硫嘌呤甲基转移酶(thiopurine S-methyltransferase，TPMT)基因常见的遗传多态性在河南地区汉族人群中的分布及其频率。

They identified 371 genes (nearly 10%) as monoallelically expressed in epigenetically stable patterns in at least one population of cells derived from a single B cell clone.

他们确认起源于一个单B细胞克隆种群的371个基因（近10％）以单等位基因性在后生遗传稳定模式中表达。

And the IC50 values of all tested compounds did not change at various times. The panel of CYP3A4 polymorphic enzymes will be tested against various drugs, kinds of fluorogenic substrates and CYP3A4-specific substrate to identify potentially adverse drug-CYP in order to generate predictive information applicable in personalized medicine.

多种荧光底物、探针底物和大量的上市药物对人细胞色素P450 3A4野生株及其突变株的体外代谢研究正在进一步进行中，旨在建立一种高通量、简便、快捷的针对于CYP3A4遗传多态性的药物筛选平台，从而为临床个体化用药提供科学依据。

Primary hepatocellular carcinoma is one of the most common neoplasms in China. Most previous experimental researches were against tumor cells which had characters of unable transmissibility, high heterotype and high mutation rate, so satisfied curative effects could not be obtained.

原发性肝癌是我国常见的恶性肿瘤之一，以往的实验研究多数针对肿瘤细胞本身，但瘤细胞具有遗传不稳定性、高突变率和高异型性等特点，因此、未能取得满意的疗效。

Comparison on the effectiveness of different cryoprotectants with chicken embryo primordial germ cells,Effect of heroin dependence on expression and function of glucagon in islet a cells of rats,Establishment of transgenic mouse line skin-specifically expressing hCTLA4-Ig,Resistance selection by meilingmycin and chlorfenapyr and activity changes of detoxicated enzymes in Tetranychus urticae.

文章摘要：鸡胚胎原始生殖细胞对不同冷冻体系适合性的研究，海洛因依赖对大鼠胰岛A细胞胰高血糖素表达和功能的影响，皮肤组织特异性表达hCTLA4-Ig转基因小鼠品系的建立，二斑叶螨对梅岭霉素和溴虫腈的抗性选育及其解毒酶活力变化，北京市褐家鼠种群遗传多态性及与汉坦病毒分布关系的研究，金乌贼同工酶分析，Nogo—A在成年大鼠脑内神经元的分布。

Objective To understand the genetic polymorphs of the D 17 S 5 locus in TCC.

目的 探讨膀胱移行细胞癌患者D17S5位点的遗传多态性。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。