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性母细胞

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Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%), 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%),Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%)恶性淋巴瘤症状, 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%)恶性淋巴瘤分期,Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

It is concluded that (1) there are no relationships between fusion rate and relativeness of the recipient cytoplasm to nucleus donor cells,(2) cytoplast of the goat MII oocyte can support the preimplantation development of SCNT embryos reconstructed with nucleus from other species,(3) the blastocyst rate of close relative inter-species SCNT embryos is higher than that of distant relative inter-species SCNT embryos.

由此结果得出以下结论:(1)山羊M II期卵母细胞胞质与供核细胞之间的亲缘性不影响两者的融合率;(2)山羊M II期卵母细胞的胞质能支持异种间体细胞核移植胚的着床前发育;(3)亲缘关系近的种间核移植胚的囊胚发育率高于亲缘关系远的种间核移植胚的。

Results The diagnostic correspondent rate of obstructive and nonobstructive azoospermia by seminal spermatogenic cells examination was 85%, 95.1% respectively. The spermatogenic arrest at spermatid level, spermatocyte level and spermatogonium level or sertoli cells only were 14, 21 and 6 cases respectively.

结果 精液生精细胞学检查对梗阻性和非梗阻性无精症分型诊断的符合率分别为85%、95.1%。41例非梗阻性无精症中,生精阻滞阶段在精子细胞、精母细胞、精原细胞分别为14例2、1例和6例。

It also indicates that the expression of WT1 is regulated strictly in time and space, and the aberrant expression of WT1 may result in retarded differentiation of blastemal cell leading NR or nephroblastoma.

提示在散发性肾母细胞瘤发生中除WT1突变外,WT1表达延迟可能是其中起重要作用的机制之一;WT1基因与肾母细胞瘤的组织分化有关,可能诱导胚基细胞向上皮细胞方向分化。

At time of 5mm length of alabatrum, the miosis in microsporecyte and the sex differentiation was found, thus in female flowers, pollen mother cell showed a abnormal meiose then the pollen cells gradually disintegrated, final, contabescence had taken, and in male flowers, the stamen normally developed.

在幼蕾长到5mm左右,即花粉母细胞开始减数分裂时,出现花性别的分化,雌花中雄蕊花粉母细胞不能进行正常减数分裂,进而花粉细胞逐步解体而导致雄蕊败育;雄花中雄蕊发育正常至性成熟。

Results 5 cases of ependymocytoma, 3 cases of astrocytoma, 1 medulloblastoma hemangioblastoma in 10 cases of intra-medullary tumor; 36 cases of neurogenic tumor, 11 cases of spinal meningioma in 47 cases of subdural extramedullary tumor; 2 cases of neurogenic tumor strided over scleromeninx;2 cases of extradural metastatic tumor, 1 cestodiasis, 2 cases of epidural hematoma, which were mistaken for hemangioma before surgical operation and 1 vascular malformation in 4 cases of intraspinal nontumorous occupying lesion.

结果:10例髓内肿瘤中,室管膜瘤5例;星形细胞瘤3例;血管母细胞瘤1例;成神经管细胞瘤1例。47例脊髓外硬膜下肿瘤中,神经源性肿瘤36例;脊膜瘤11例。2例跨硬膜内外生长的神经源性肿瘤2例。硬膜外的转移瘤2例。4例椎管内非肿瘤性占位性病变中,椎管内绦虫病1例;硬膜外血肿2例,术前误为血管瘤;血管畸形1例。

A pure and single K+ current of ultrarapid delayed rectifier K+ current or transient outware K+ current is respectively expressed on Xenopus Oocytes. This is a moderm pharmacological model for evaluation class Ⅲ antiarrhythmiv durgs, overcomes many defcts such as lacking human fresh cardiac muscle cells as material and co-expression of many currents on cell membrane. A new compound A1998 from Ocean material is evaluated in this model for class Ⅲ antiarrhythmic functions.

5和Kv4.2cDNA转录为mRNA,然后将其分别注入蟾蜍卵母细胞上:在蟾蜍卵母细胞上分别获得纯净、单一的超速延迟性整流钾电流(Ikur,ultrarapid delayed rectifier K+current)和瞬间外向钾电流(Ito,transient outward K+current)表达,克服以往在筛选评价抗心律失常药物时,人新鲜心肌细胞取材困难、多种电流在细胞膜表面共同表达等缺点,从而建立评价Ⅲ类抗心律失常药物的先进药理模型,并筛选具有Ⅲ类抗心律失常药理作用的新化合物A1998。

Results Tag was found in all of 8 ependymomas, 2 choroid plexus papillomas, 2 human glioma cell lines, 90% of pituitary adenomas (9/10), 73% of astrocytomas (11/15), 70% of meningiomas (7/10), 50% of glioblastomas multiforme (4/8), and 33% of medulloblastomas (2/6). None of the 8 normal brain tissues were positive for Tag, nor were 5 oligodendrogliomas and 1 pineocytoma.

结果 Tag在8例室管膜瘤、2例脉络丛乳头状瘤及2株人脑胶质瘤细胞系中全部表达;垂体腺瘤Tag阳性率为90%(9/10),星形胶质细胞瘤73%(11/15),脑膜瘤70%(7/10),多形性胶质母细胞瘤50%(4/8),髓母细胞瘤33%(2/6);5例少枝胶质细胞瘤、1例松果体瘤及8例正常人脑组织无Tag表达。

The meiosis of oocytes differ from mitoses of general cells. Especially in most mammalian species, oocytes are formed during fetal life, but they are arrested at the prophase stage of the first meiotic division until around the time of ovulation.

卵母细胞的成熟分裂有别于一般细胞的有丝分裂,尤其是哺乳动物,在胎儿期或出生后不久,初级卵母细胞就陆续进入第一次成熟分裂前期阶段,但长时间的&休止&于此期,直到性成熟时在促性腺激素等因素的作用下,第一次成熟分裂才重新启动。

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