性原细胞

P1 BMSCs, P3 CCs, and P3 ADAS were implanted into collagen/hyaluronic acid scaffold at different concentrations of 10%, 20%, 50%, 80%, and 100%, and the cells were then three-dimensionally cultured in serum-free culture media. Two weeks later, SO staining and immunohistochemical staining were employed to observe the synthesis between of chondroitin sulfate and type II collagen.

取P1骨髓间充质干细胞，P3软骨细胞和P3脂肪源性成熟基质细胞种植入不同比例(10%，20%，50%，80%，100%)的胶原/透明质酸支架中，在无血清培养液中三维培养。2周后，用SO染色和免疫组织化学染色分析，观察硫酸软骨素和Ⅱ型胶原合成情况。

Results Many endothelial cells were observed with higher vigor and adherance to the wall after incubation for 3-5h, and spreaded to form cell masses for 12-24h, and grew densely and converged into single layer which characteristically arranged to cobble-stone shape after incubation for 1-2 weeks.

结果 原代细胞培养3~5h后，大部分活力较高的内皮细胞已开始贴壁，12~24h后，内皮细胞己铺展形成由数个细胞组成的细胞群，1~2w后，细胞呈生长密集状并汇合形成单层，在倒置相差显微镜下，呈特征性"鹅卵石状"或"铺路石状"镶嵌排列生长。

Any of a group of microorganisms of the genus Chlamydia that are obligate intracellular parasite s and include the causative agents of trachoma,psittacosis,and lymphogranuloma venereum.

衣原体属微生物，贝宗体属微生物一种衣原体属微生物群，是一种专性细胞内的寄生虫，包括颗粒性结膜炎、鹦鹉病、淋巴肉芽肿的病原体

In this report, we analyzed the cellular and noncellular findings of bronchoalveolar lavage fluid in 18 cases with IPF, 12 patients with Sar and 9 healthy volunteers as conirols, using immunohistochemicat staining, we also have estimted collagen typeⅠ and type Ⅲ semiquantitatively in transbronchial lung biopsy specimens from 25 patients with IPF and 10 normal lung tissue. The aim of this investigation is to select the criteria for evaluating the disease actiity.

本文对18例IPF、12例Sar和9例正常对照者的支气管肺泡灌洗液中细胞成份和非细胞成份进行了检测和分析，同时对10例正常肺和25例IPF患者经支气管肺活检的肺组织标本，应用免疫组化方法、半定量剂检测其中Ⅰ型胶原和Ⅲ型胶原的含量结合临床治疗效果，对有助于疾病活动性判断的指标进行了筛选和进一步的评价。

In order to overcome the shortcomings of acellular dermal matrix used as tissue engineering scaffold material, such as bad permeability, low degradation speed, and strong immunogenicity, a new type of collagen scaffold was prepared by applying various chemical, biological and physical comprehensive methods to deal with pigskin. The microstructure of the scaffold was observed under photomicroscope and scanning electron microscopy, and the in vitro degradation time, permeability, tensile-strength, porosity, shrinkage temperature were tested.

为了克服猪脱细胞真皮基质作为组织工程支架材料渗透性差、降解速度过慢、免疫原性较强等缺点，采用多种化学、生物与物理综合方法处理猪皮制备了一种新型天然胶原支架材料，通过光学显微镜、扫描电镜观察以及体外降解时间、透水汽性、拉伸强度、孔隙率、收缩温度等的测定，对其性能进行了研究。

It is well known that retinal pigment epithelial cells are predominant proliferative cells in PVR which is an excessively wound healing response occurring after RPE cell wounding. The activated RPE cells migrate from their normal, sessile state to vitreous and onto both surfaces of the retina, in which they begin to dedifferentiate, migrate, proliferate, change phenotype and secrete ECM.

既往研究证明视网膜色素上皮(retinal pigmentepithelial，RPE)细胞是参与PVR的主要细胞，PVR是视网膜脱离后RPE细胞损伤的一种自我修复过程，是一种过度的眼内创伤修复反应；RPE细胞在正常位置上处于静止状态，而在某些病理条件下，如视网膜裂孔形成和视网膜脱离后，RPE细胞脱离原位，开始去分化、移行、增生、发生表型转化并分泌胶原等ECM，最终在视网膜前后表面和玻璃体内形成具有收缩能力的增生膜，造成牵拉性视网膜脱离。

A clear cause-and-effect relationship between excessive myocardial MMP-1 activity, increased mysial collagen degradation, and progression to systolic HF has been shown experimentally through the use of transgenic models and the use of pharmacological MMP activators.53,54 In addition, experimental evidence has been provided showing that following chronic neurohormonal activation, increased synthesis and release of MMPs into the local extracellular matrix of the cardiomyocyte occurs,55 which in turn could contribute to endomysial and perimysial collagen degradation and disruption.

一个明显的因果过多的心肌MMP-1关系活动， mysial增加胶原蛋白的降解和进展收缩性心力衰竭已被证明试验，通过使用转基因模型和使用的MMP药理作用此外，activators.53，54实验证据下面被提供显示慢性神经激活时，增加的MMPs合成和释放到当地的细胞外基质的心肌细胞发生，55反过来有助于人肌内膜和 perimysial胶原退化和破坏。

Of them 25 cases of oral cancer (G1-2) were randomly divided into trail and control group . The remained 11 cases of nasopharyngeal and maxillary sinus cancer (NPC-MSC, mainly G3-4) were attributed to a third group (1st course: sBRM, then 2nd course: IAC). The order of drug-use of sBRM is: pre-immunomodulation of the reactivity of patient low-dose CTX and PolyI∶C, then in- juring tumor and thereby modulation of its immunogeneity (DDP-PYM regimen , thereafter, reaction enhancement modu- lation [low-dose rhuIL-2, Cimetidine and Indomethacin ] . All drugs, except for CTX, PolyI∶C and Indo, were fractionally delivered in a manner of continously infution in 8-10 hours via a retaining intra-external carotid artery catheter CAVAFIX 335 SPLITTOCAN G14, B.

将其中25例晚期口腔高、中分化鳞癌病人随机分为实验治疗（12例）和对照治疗（13例）两组，实验组采用sBRM疗法，具体用药为：先用小剂量环磷酰胺和聚肌胞对机体反应性作预调变，然后用低剂量DDP-PYM化疗杀伤&致创&癌细胞，使其免疫原性增强并借之诱导肿瘤浸润淋巴细胞，化疗结束后续用小剂量rhuIL-2激活和扩增TIL，特别是其中的T细胞，并借助小剂量西咪替丁、消炎痛调节机体以原发灶为中心的癌受创相关反应。

Nither CDMP-1, nor cryopreservation can effect cell cycle of the chondrocytes.

结果：残耳软骨细胞在体外培养时随代数增加呈异染性的糖胺多糖减少，第1、3代Ⅱ型胶原阳性细胞比例约68％/～71％，第5代为23％、显著降低；冻存后第3代为65％，与同代数的细胞没有差别，100ng/ml浓度的CDMP-1可以将第4代细胞的阳性比例维持在66％，而且冻存和生长因子不会引起细胞周期的变化。

Objective To investigate the potential pathogenicity of Mycoplasma penetrans (M. penetrans), and to study nitric oxide production and cell prolification in lipid-associated membrane proteins-stimulated mouse macrophages.

目的 检测穿透支原体脂质相关膜蛋白能否诱导小鼠巨噬细胞产生一氧化氮及其对细胞增殖的影响，以了解穿透支原体潜在的致病性。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐