心肌内的

Objective:To explore the effects of aldosterone antagonism spironolactone on cardiac fibrosis in patients with essential hypertension.

目的 ：观察醛固酮拮抗剂———螺内酯对原发性高血压患者心肌纤维化的影响。

Objective To study the protective effect of coenzyme complex on myocardium under cardiopulmonary bypass in open heart surgery.

目的 观察辅酶复合物在体外循环心内直视术中的心肌保护作用。

METHODS We used a dermatome to obtain thin endocardium, midcardium and epicardium transmural strips from left ventricular free wall of canine (weight 15-18 kg) and standard microelectrode techniques to record and measure the transmembrane action potential duration.

应用标准玻璃微电极技术，在不同频率刺激下，记录应用胺碘酮前后犬左室游离壁内、外膜及中层心肌细胞跨膜动作电位各种参数的变化。

ResultsMacroscopic examination showed no excrescence,thrombus formation,arm fractures and corrosion.The devices were covered with collagen fibrosis and discrete endocardial cells,apparent inflammatory infiltration in the devices and around the devices 1 month after implantation.The implants were nearly endothelialized,while the inflammatory reaction relieved gradually,with myocardial cells ingrowth at the edges of the device 3 months after implantation.The devices were completely covered with endocardium and fibrous tissue.Moreover,endothelial cells could be found on the smooth microscrew adaptor.The inflammatory reaction diminished with a few chronic inflammatory cells existing.Neovascularization and lymphatic vessels ingrowth could be observed 6 months after implantation.

结果所有封堵装置表面均没有发现赘生物、血栓形成、支架发生断裂及被腐蚀；术后1个月，封堵装置表面被胶原纤维和散在内皮细胞所覆盖，大量炎症细胞浸润，封堵装置边缘有小灶性炎症细胞浸润；术后3个月，封堵装置表面几乎被内皮细胞所覆盖，炎症细胞较1个月时明显减少，封堵装置内见纤维化，封堵装置边缘心肌细胞浸入；术后6个月，封堵装置表面完全被心内膜和纤维组织所覆盖，伞尖表面光滑并有内皮细胞上爬，炎症反应明显消散，但仍有少量慢性炎症细胞存在，装置内有新生的血管、淋巴管长入。

Objective To evaluate the value of intracardiac tissue velocity imaging for showing the myocardial excitation and conduction.

目的：评价心腔内组织多普勒速度图模式对心肌异常激动及传导的显像功能。

The latter depresses the activity of Na(superscript +)-K(superscript +)-ATPase by down-regulating the gene expression of α1,α2,α3 and β1 isoforms of sodium pump in myocardial membrane, and also induces intramitochondrial calcium overload, thereby mediates MIR injury.

内洋地黄素特异性拮抗剂地高辛抗血清通过阻断内洋地黄素的生物学作用，上调钠泵各亚基的基因表达，发挥其抗心肌缺血再灌注损伤的作用。

Aim: To determine whether activation of κ-opioid receptor with U50,4 88 H, a selective κ-opioid receptor agonist, produces any changes in electrical u ncoupling during prolonged ischemia and whether these changes in electrical unco upling is associated with the cardioprotection induced by κ-opioid receptor ac tivation, and to explore the possible mechanism.

测量指标：以分光光度计在490nm波长下测定氯化三苯基四氯唑与活细胞反应的产物formazan含量的方法测定心肌细胞活性、测定冠脉流出液中乳酸脱氢酶的含量以及心室内压；②全心停灌70min，应用四电极法观察不同浓度U50，488H、nor-BNI和5-HD对缺血期间心肌整体阻抗和电脱耦联参数(电脱耦联时间、平台时间、电脱耦联最大速率和阻抗倍数)的影响。

The introduction combines traditional Chinese and Western medicine below the experience of enteritis of noxiousness of fine ailment of remedial Tibet mastiff, in order to offer reference. 1 hair sick condition and clinical expression ill dog are 2~4 month more age young dog, majority is come on suddenly, anorexia or abandon absolutely, mental depressed, systemic symptom worsens quickly, produce acuteness sex vomiting and diarrhoea, puke is first feed rotten, afterwards is yellow or olive bubble mucus and hematic type thing, have diarrhoea dung has the sticky stiff thing of grey yellow, turn after for rare dung of effluvial shape of embedded mucous membrane, then shows hematic dysentery, because ill dog is acuteness vomiting and diarrhoea are rapid dehydration, eyeball cave in, temperature is shown two-way and calorific,℃ of the 40~41 at the beginning of disease, 1~2d falls it is normal to come, after 3~4d answer elevatory, die very quickly next, 4~5d of course of diseases, the temperature when on one's deathbed drops more to normal temperature the following. Bottom of stomach of dog of die in one's bed of 2 analyse check has haemorrhage sex inflammation, show cardinal, small intestine mucous membrane falls off, alvine wall attenuates, there is gules mucus inside, mix inside large intestine have show wine blood excrement and urine, there are a lot of haemorrhage places on mucous membrane, haemorrhage of rectum mucous membrane is more, mesentery lymph node enlargement, sometimes afterwards sends intussusception, alvine tangent plane bleeds, cardiac muscle is loose, color becomes weak, cystic plentiful, liver is qualitative fragile and brittle. 3 diagnose 3.1 epidemiology to diagnose this ill much hair at young dog, rather dog of epidemic disease have an inoculation feels the most easily, be affected directly or affect secondhand, basically pass enteron infection, this disease all can happen all the year round, but with cold...

下面介绍中西医结合治疗藏獒细小病毒性肠炎的心得，以供参考。1发病情况和临床表现病犬多为2~4月龄幼犬，多数为忽然发病，食欲减退或废绝，精神沉郁，全身症状急剧恶化，发生剧烈性呕吐和腹泻，呕吐物先为食糜，继为黄色或黄绿色泡沫黏液和血样物，泻粪有灰黄色的黏稠物，后转为恶臭的内含黏膜状稀粪，继而呈血痢，由于病犬剧烈呕吐和腹泻迅速脱水，眼球下陷，体温呈双向发热，病初40~41℃，1~2d降至正常，3~4d后又复升高，然后很快死亡，病程4~5d，临死时体温多下降至常温以下。2剖检病死犬胃底部有出血性炎症，呈深红色，小肠黏膜脱落，肠壁变薄，内有红色黏液，大肠内混有呈暗红色血液粪便，黏膜上有许多出血点，直肠黏膜出血较多，肠系膜淋巴结肿大，有时继发肠套叠，肠切面出血，心肌松软，颜色变淡，胆囊充盈，肝质脆而易碎。3诊断3.1流行病学诊断本病多发于幼犬，未免疫接种犬最易感，直接感染或间接感染，主要通过消化道感染，该病一年四季均可发生，但以寒。。。

METHODS: 8-Bromo-cAMP and sodium nitroprusside were added into the media to raise the concentrations of cAMP and cGMP of cultured cardiomyocytes, in situ hybridization and immunohistochemistry methods were used to identify the mRNA and protein expression of bFGF. The amount of bFGF mRNA and protein expression were detected by computor imaging analysis system MIAS exe.

分离培养大鼠心肌细胞，加入8-溴-cAMP和硝普钠，升高细胞内cAMP、cGMP浓度，用原位杂交及免疫细胞化学的方法观察细胞内bFGF的表达，图象分析检测bFGF表达量的变化。

Methods: The motion of parasternal papillary muscle anterior wall, inferior wall, posterior wall, and lateral wall were detected by 2DE at short axis view of left ventricle before PTCA, 3 d and 1-3 months after PTCA in 33 cases of patients with coronary heart disease, who received PTCA+stent at selected time. Peak systolic velocity of subendocardial, subepicardial and middle layer myocardium, transmural velocity difference of the same segments and Outer lateral mitral valve annulus were also detected at apical 4 chamber view by pulsed wave tissue Doppler imaging.

对33例择期行PTCA+支架术的冠心病患者用HP5500型超声诊断仪，于PTCA术前及术后3d、1-3个月对胸骨旁左心室乳头肌短轴切面的前间壁、下壁、后壁、侧壁行二维超声心动图(2DE)检测各节段的室壁运动情况，用脉冲组织多普勒成像检测上述各节段的内、外膜下及中层心肌的收缩期峰值速度，内外膜下心肌的收缩速度差及心尖四腔观二尖瓣外侧环的收缩期峰值速度。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。