心肌内的

The artide focused on the cellule and molecule character of myocardic ischemia and ischemical reperfusion injury induced by strength training, the essential feature of strength training preconditioning and the signal transduction mechanism and the intra-cellular effector of myocardial preservation, proposing the research strategy, concrescencing the theory of contemporary strength training, clarifying some hot questions and important future directions on endogenous myocardial protection of strength training.

就力量运动引起相对心肌缺血及缺血再灌注损伤的细胞分子学特点、力量运动缺血预处理的基本特征及心肌保护作用的细胞信号转导机制与细胞内效应器及存在的问题进行阐述，提出研究策略。

The results indicated that MCA could improve the left ventricular systolic function in patients with conge stive heart failure and the mechanism possibly included the effects of increased the concentration of intracellular cAMP and protective on cardiomyocytes anoxi a injury.

结果显示，心先安能改善心力衰竭心肌梗死患者的左室收缩功能，其机制可能与升高很痒细胞内cAMP浓度、保护缺氧受损的心肌很痒细胞有关。

Dephosphorylated PLB inhibits SERCA_(2a) activity, whereas phosphorylated PLB dissociates from SERCA_(2a) and leads to enhanced contractibility.

反义PLB转染心肌细胞能有效抑制细胞内PLB的表达，增强SERCA活性，因而改善心肌梗死大鼠的心脏收缩功能。

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

H%Otjs%}'D$IYo%^+F0 Objective To appraise objectively the myocardial protective effect of beating heart with mild hypothermia and cardiopulmonary bypass with cardiac arrest by cold cardioplegia perfusion during openheart operation for mitral valve replacement.

目的 用体视学定量法对比分析两种二尖瓣置换术对心肌超微结构的影响，旨在为浅低温体外循环心脏不停跳心内直视手术对心肌保护效果作进一步客观的评价。

Application of SOD and /or Hypoxia-preconditioning can prevent myocardiac injury partly by reducing the myocyte apoptosis.

SOD和或缺氧预处理具有抗心肌细胞损伤和减轻心肌细胞凋亡的作用，而且可能是通过降低细胞内钙离子浓度而起作用的。

In normal myocardium, sorcin extensively co-localized with ryanodine receptors, whereas in myopathic hearts, the degree of co-localization was markedly disrupted.

正常心肌细胞中，sorcin与细胞内钙释放通道RyR能广泛协同定位，而在心肌病的心肌细胞中，这种协同定位的能力被破坏。

GB could inhibit fluorescence recovery rate of the cells after laser bleaching.Our data indecated that GB might inhibit cell-cell communication via pathway of changing function of Gap j unctions.

本研究利用荧光光漂白后荧光重新分布技术观察了体外培养的大鼠心肌细胞通讯功能并探讨了银杏内酯 B对大鼠心肌细胞通讯功能的影响。

Results: The CO pretreatment group received pre-exposure to 250 ppm of CO significantly reduced the expression of CHOP in the heart compared with I-R group; however, hypoxia pretreatment group showed no such effect.

吸入低浓度的CO（250 ppm）能明显改善心肌缺血-再灌注损伤；其机制可能为外源性CO缓解缺血-再灌注激发的过度内质网应激，抑制CHOP过表达，减轻ERS相关细胞凋亡的发生，从而减轻心肌缺血-再灌注损伤。

In the third part, cultured H9C2 myocytes were randomly divided into two groups, the control group and 200mol/L DZ preconditioning group.

第三部分，培养的H9C2心肌细胞随机分成2组，即对照组和200mol/L DZ预处理组，分别富集两组细胞的磷酸化蛋白质，采用双向电泳和质谱技术，分离鉴定DZ预处理后心肌细胞内磷酸化蛋白的差异表达。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。