心肌

Activities of chymase and ACE were tested by radioimmunological method. Expressions of phosphoric extracellular signal regulated kinase 1/2 (p-ERK1/2) in hearts were measured by western blot. Results: As compared to the control group levels of GSP, myocardial enzymes and myocardial Ang Ⅱ were much lower in those of APS group.

心肌组织的血管紧张素Ⅱ含量；RT-PCR法检测心肌糜酶和血管紧张素转换酶 mRNA表达；放免法检测chymase和ACE的活性；免疫蛋白印迹法检测心肌磷酸化的细胞外信号调节激酶1/2(p-ERK1/2)含量。

Results As compared to DM control group, levels of GSP, myocardial enzymes and myocardial Ang Ⅱ were much lower in APS group, while levels of insulin, C-peptide and plasma Ang Ⅱ were the same. Levels of expression of collagen Ⅰ and the ratio of collagen Ⅰ/collagen Ⅲ in APS group were lower than those in DM group. APS group showed lower levels of chymase mRNA expression and activity than those in DM control group, while there was no diference in ACE mRNA expression and activity between the two groups.

结果 APS组血糖、糖化血清蛋白、心肌酶谱和心肌Ang Ⅱ水平较DM组显著下降，胰岛素、C肽、血浆AngⅡ水平和DM组无差异；APS组心肌Ⅰ型胶原表达和Ⅰ/Ⅲ型胶原比值较DM组显著下降；APS组chymase mRNA表达和活性均显著低于DM组，ACE基因的表达和活性与DM组无显著性差异。

While levels of insulin. C-peptide and plasma Ang Ⅱ were similar. APS group showed lower levels of chymase mRNA expression and activity than those of DM control group, while there was no diference in ACE mRNA expression and activity between two groups. Compared with DM group, expression level of p-ERK1/2 in APS group was much lower.

结果：APS治疗组GSP、心肌酶谱和心肌AngⅡ水平较对照组显著下降；血胰岛素、C肽、血浆AngⅡ水平与对照组无显著差异；APS组chymase mRNA表达和活性均显著低于对照组，ACE基因的表达和活性与对照组无显著差异；APS组心肌p-ERK1/2含量较对照组明显降低。

Results Compared with the model group, crocetin can significantly reduce the cardiac indexes, obviously decrease the level of MDA, LDH and CK in the serum. Crocetin can significantly increase the activities of Na +, K +-ATPase; Ca 2+, Mg 2+-APTase; GSH-Px. The histopathological changes confirmed the protective effects of crocetin on the myocardial injury.

结果 西红花酸能显著降低血清中CK和LDH的释放；也能显著降低血清和心脏匀浆中MDA水平，心脏重量参数显示对心肌水肿有明显的抑制作用；保护心肌GSH—Px；Na^ ，K^ —ATP酶和Ca^2 ，M8^2 -ATP酶活性，心脏病理切片表明西红花酿对心肌坏死有显著的保护作用。

A total of 90 healthy male Sprague Dawley rats were selected for this study. Twelve rats were used for the sham operation group. Left anterior descending coronary artery of the remaining rats was deligated to establish models of myocardial infarction. After 24 hours of deligation, 36 rats were randomly divided into the control group and experimental group, 18 rat in each group.

目的：检测人胰岛素样生长因子Ⅰ基因修饰的鼠骨骼肌成肌细胞移植后，心肌梗死大鼠血浆及心肌组织内胰岛素样生长因子Ⅰ蛋白浓度的变化，以及心肌细胞内胰岛素样生长因子Ⅰ和端粒酶反转录酶mRNA水平的表达。

Methods:161 patients with chronic stable angina pectoris were treated with Elantan Long or isosorbide dinitrate.

对161例慢性稳定型心绞痛患者进行长效异乐定与硝酸异山梨酯对比治疗的临床观察，并采用Holter 24h心肌缺血总负荷及放射核素心肌灌注显像评估缺血心肌面积。

Objective To evaluate the effect of modified myocardial preservation for surgical treatment of inˉfant tetralogy of Fallot.Methods Fifty-sixinfants,39male and17female with age from3months to12months from January,1997to July,2003were studied.All patients had one stage surgical correction with traditional myocarˉdial preservation（36cases）or modified myocardial preservation（20cases）.

目的 评价改良心肌保护对婴儿法洛四联症期手术治疗的影响方法 1997年1月～2003年7月对56例婴儿法洛四联症病人行一期手术治疗，男39例，女17例，年龄3～12月，平均（9.36±2.80）月，体重3.511kg，平均（8.83±1.25）kg.36例采用传统心肌保护，20例采用改良心肌保护。

Receiving signals from any kinds of cascades, a number of transcription factors have been implicated as direct mediators of hypertrophic gene expression including SPl, Elk-1, SRF, MEF-2, GATA, and LIM proteins.

目前虽然认为心肌肥大的发病机制与细胞外的心肌肥大因子刺激、细胞内的信号转导和核内的某些基因活化有关，但其最本质的特征是心肌细胞基因表达的异常。

(1) Dobutamine can significantly increase 〓 exchange currents of ventricular myocytes in normal and hypertrophied rats, and the sensitivety to dobutamine in hypertrophied cells is decreased.

（1）多巴酚丁胺可显著增加正常大鼠和心肌肥厚大鼠心肌细胞的〓交换电流，但对肥厚心肌细胞的效应下降。

Objective: To investigate the effect of intramyocardial bone marrow cell injection on myocardial perfusion and LV function in patients with chronic myocardial ischemia.

目的：研究骨髓干细胞心肌内注射对慢性心肌缺血患者心肌灌注及左室功能的影响。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。