心肌

ResultsMacroscopic examination showed no excrescence,thrombus formation,arm fractures and corrosion.The devices were covered with collagen fibrosis and discrete endocardial cells,apparent inflammatory infiltration in the devices and around the devices 1 month after implantation.The implants were nearly endothelialized,while the inflammatory reaction relieved gradually,with myocardial cells ingrowth at the edges of the device 3 months after implantation.The devices were completely covered with endocardium and fibrous tissue.Moreover,endothelial cells could be found on the smooth microscrew adaptor.The inflammatory reaction diminished with a few chronic inflammatory cells existing.Neovascularization and lymphatic vessels ingrowth could be observed 6 months after implantation.

结果所有封堵装置表面均没有发现赘生物、血栓形成、支架发生断裂及被腐蚀；术后1个月，封堵装置表面被胶原纤维和散在内皮细胞所覆盖，大量炎症细胞浸润，封堵装置边缘有小灶性炎症细胞浸润；术后3个月，封堵装置表面几乎被内皮细胞所覆盖，炎症细胞较1个月时明显减少，封堵装置内见纤维化，封堵装置边缘心肌细胞浸入；术后6个月，封堵装置表面完全被心内膜和纤维组织所覆盖，伞尖表面光滑并有内皮细胞上爬，炎症反应明显消散，但仍有少量慢性炎症细胞存在，装置内有新生的血管、淋巴管长入。

Objective To explore the variation of the exon 11 of MEF2A gene in patients with acute myocardial infarction.

目的 研究MEF2A基因第11外显子在普通急性心肌梗死患者中的变异情况。

Although cellular recovery and improvement in ventricular function are observed, the degree of clinical recovery is insufficient for device explantation in most patients with chronic heart failure.

尽管已经观察到心肌细胞的恢复和射血分数的改善，但是在多数心衰病人移出辅助装置后，临床恢复程度仍然不够。

Histological analysis was performed on myocardial samples taken at LVAD implantation and explantation.

对LVAD植入或移出时获得的心肌标本进行组织学分析。67例心衰病人入选本研究。

Although cellular recoery and improement in entricular function are obsered, the degree of clinical recoery is insufficient for deice explantation in most patients with chronic heart failure.

尽管已经观察到心肌细胞的恢复和射血分数的改善，但是在多数心衰病人移出辅助装置后，临床恢复程度仍然不够。

Eleven of the 15 patients had sufficient myocardial recovery to undergo explantation of the left ventricular assist device a mean of 320±186 days after implantation of the device. One patient died of intractable arrhythmias 24 hours after explantation; another died of carcinoma of the lung 27 months after explantation.

结果：植入左室辅助装置后经过平均320±186天的随访，15例病人中有11例心肌功能得到有效恢复。1例在植入后24小时死于难治性心律失常，另外1例在植入27个月后死于肺癌。

OBJECTIVE To study the effects of Herba Epimedii extractive on myocardial ischemia in rats.

目的 研究淫羊藿提取物对大鼠急性心肌缺血的影响。

The mechanism of this protective effect appears to be related to inhibition of neutrophil extravasation, a critical step in neutrophil-induced myocardial reperfusion injury.

这防护的作用的机制在看来被联系到好中性的外渗的禁止，在好中性劝诱的批评的步心肌的reperfusion伤害。

Shafie Fazel, cardiac surgery resident at TGH, University of Toronto surgeon/scientist program fellow and lead author of the study entitled,"Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines," published today in The Journal of Clinical Investigation. When damaged heart tissue sends out an 'SOS' distress signal, this subset of bone marrow cells mobilizes quickly and stimulates the growth of new blood vessels in the heart.

一名来自多伦多大学的外科医生/科学家计划研究组的的成员，同时也是今天发表在《临床研究》中的"产生于骨髓的心脏保护细胞----C-kit+细胞调节着心肌血管生成因子的平衡"论文的主要作者----特里普勒总医院心外科住院医师这样描述，当心脏细胞受损时发出'SOS'的求救信号，这种骨髓细胞亚群快速动员和刺激新生心脏血管的生长。

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。