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Methods: We evaluated the precommercial highly sensitive cardiac troponin T assay from Roche Diagnostics and the Architect cardiac troponin I (cTnI-Architect) assay from Abbott Diagnostics by testing samples from a reference population of 546 individuals and a cohort of 85 marathon runners.

通过测定处于参考范围的546人和85位马拉松运动员的样品,我们评估了罗氏公司上市前的高敏心肌肌钙蛋白T和雅培公司开发的建筑师心肌肌钙蛋白I( cTnI-Architect)。

It has been ratified by nativemedicine supervisory bureau and in the third stage ofclinical obserbison.The study took acute myocardialischemia rabbit as animal model and long Xin Luo capsuleas control medicine.We proke into the mechanism of actionof Yi Xin capsule on preventing and curing myocardialischemia.

本研究以急性心肌缺血家兔作为动物模型,以通心络胶囊作为对照药,从血管生物学效应、病理形态学及超微结构等方面,探讨了益心胶囊防治心肌缺血的确切作用机制。

Methods:Cardiac muscle of twoday neonate rattus was digested repeatedly by 0.0625% trypsin.The cardiocytes were collected in DMEM medium,which contains 10% fetal bovine serum.Myocardial cells were isolated with the technique of differential anchoring velocity with 90 min and were pured by Brdu.The cardiocytes were placed into CO2 incubator to incubate seven days after their purification.

应用0.0625%的胰蛋白酶重复消化出生第2 d乳鼠的心肌组织多次,收集的细胞用含10%胎牛血清的DMEM培养基中和,用差速贴壁分离法分离,在以溴脱氧尿嘧啶纯化心肌细胞后置CO2培养箱孵育7 d。

Medicine,surgery and intervention operation can t substitute the putrescent tissue and prevent ventricular remodeling , Although they can improve the cardiac function.

尽管药物疗法、手术治疗和介入治疗可以改善患者的心脏功能,但是都不可替代坏死的心肌组织及阻止心肌重构的发生。

Methods: To create the model of myocardial infarction, to detect the serum SOD and LPO of the MI rats by the pyrogallic acid self-oxidation and detect myocardium tissue ROS of the MI rats by flow cytometry.

建立IR心肌梗死动物模型,采用邻苯三酚自氧化法检测梗死大鼠血清超氧化物歧化酶、过氧化脂质;运用流式细胞术检测梗死大鼠心肌组织中性粒细胞活性氧。

Among these 110 patients, 20 patients were followed up 3 to 6 months for investigating the cor- rection of the change of cardiac function with the level of serum cTnI/cTnT.

扩张型心肌病患者可能存在慢性心肌损伤,其损伤程度在LVEF 30%~41%可能较重;慢性心衰患者肾功能损害对血清cTnT的影响较大,而cTnI不变,因此血清cTnI可作为评判慢性心肌损伤的特异指标。

GSTT has protective effects on acute myocardial ischemia induced by ligating left coronary artery in rats in vivo, which is closely related to enhancing removement of free radicals by increasing SOD content, decreasing the leakage of LDH, and inhibiting the apoptosis of cardiomyocytes.

GSTT对结扎大鼠左冠状动脉前降支引起的急性心肌缺血损伤具有保护作用,保护作用通过升高SOD,清除自由基的能力增强及LDH的释出减少进而抑制心肌细胞凋亡。

To the clinical medicine, it is a great development that the acute myocar- dial infarct patients have been cured by coronary artery repatency, thromboclasis, precutaneous transluminal coronary angioplasty and other heart surgery in the last years. The myocardial tissue receives blood reperfusion again due to cardiovascular repatency or reconstructive operation, which can really obtain favorable therapeutic efficacy in multitudinous conditions.

急性心肌梗死病人采用冠脉再通术、溶栓治疗以及其他心脏外科手术是近年来临床医学的一大重要进展,因为缺血后疏通血管或再造血管使心肌组织得到血液的再灌注,在多数情况下确能收到良好的治疗效果。

Objective To study the resumable effects of autologous skeletal muscle satellite cell implantation on the remnant myocardial dissociated Ca 2+ distribution and the Ca 2+ wave.

目的研究骨骼肌卫星细胞移植对梗塞心肌残存心肌细胞游离Ca2 +分布及Ca2 +波的恢复作用。

Myspalax cansus (Rodentia, Myospalacinae, Myspalax)which lives on the loess plateau of our country. This unique underground rats life-long living under the cave, it developed many hypoxic tolerance protect mechanism to adapt its special circumstances at in organsall levels. In this study,we used Gansu zokor and SD rats (Sprague-Dawley)for the object, do serious hypoxia tolerance experiment, to explore the hypoxia tolerance extreme of Gansu zokor, analysis the difference hypoxia tolerance between Gansu zokor and SD rats at same oxygen concentration; The changes on their cardiac muscle organization structures in hypoxia tolerance process ; The expression of HSP70 between normoxic and hypoxic control in cardiac muscle organization of two animals , to find the relativity in all the results.

甘肃鼢鼠隶属啮齿目,鼢鼠亚科,鼢鼠属,是我国黄土高原特有地下鼠,由于终生营地下洞穴生活,使得甘肃鼢鼠发展出良好的低氧耐受保护机制,本研究以甘肃鼢鼠和SD大白鼠(Sprague-Dawley)为对象,进行低氧耐受实验,探寻甘肃鼢鼠的低氧耐受极限,比较二者低氧耐受的差异;以及低氧耐受不同时程,二者心肌组织显微和超微结构的变化差异;比较分析左心室组织中HSP70的表达变化和心肌耐受过程中组织结构变化的相关性。

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