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Results: Time and concentration of poison dying all had effect on the myocardial contracts dint and myocardial enzymogram of Bufo bufo gargarizans.

结果:除草剂丁草胺的染毒时间和浓度均可影响蟾蜍心肌收缩力和心肌梅谱。

Myocardial protection in the present research is still mainly concentrated in the low temperature,cardioplegia,the myocardial protective effect of drugs,perfusion methods.

目前有关心肌保护的研究课题仍主要集中在低温、心脏停跳液、对心肌有保护作用的药物、灌注方法等方面。

To summarize, theinjection of Carthamus tinctorius has function of protective and therapeutical effect on rats with acute myocardial ischemia.

提示红花注射液对急性心肌缺血所致的大鼠心脏损害可通过改善缺血心肌功能,抑制心脏损伤后的炎症反应,影响凋亡相关基因的表达而具有保护和治疗作用。

METHODS: NE has been shown to be a potent stimulator for neonatal rat ventricular myocyte hypertrophy in vitro. We used the activator of PPAR γ, the inhibitor of protein kinase C chelerythrine to influence protein content.3H?

在培养新生大鼠心肌细胞中,采用RSG,PKC的激动剂佛波醇酯,NE和PKC的阻断剂白屈菜季氨碱观察罗格列酮在NE和PMA诱导心肌肥大中对PKC活性和c?

However it was shown its eventually inhibiting effect on apoptotic myocyte cells during I〓 R〓h (P<0.05); The PKC inhibitors chelerythrine and scutellarein have no effect on expression of Fas protein, whereas they can significantly upregulate the expression of Bcl-2 protein.

4PKC激活剂PMA可下调Fas基因的蛋白表达,对Bcl-2蛋白的表达也有抑制作用,它对缺血30min、再灌注24h后心肌凋亡细胞的最终影响为抑制效应(P<0.05),而PKC抑制剂CHE、灯盏花素对Fas基因蛋白表达无明显干预影响,但对Bcl-2蛋白表达呈显著上调作用,故对心肌细胞凋亡的抑制作用更为明显(P<0.01)。

Cholic acids caused an increase in the concentration of Cytosolic free calcium in a dose-dependent manner.

胆酸对心肌细胞存活率的抑制作用有很强的时间-浓度依赖性,这种抑制作用除了对心肌细胞的直接损伤外,还可能与其造成细胞内&钙超载&有关。

APS is effective in treating diabetic cardiomyopathy, with inhibition of chymase relied Ang Ⅱ in diabetic cardiomyopathy.

结论APS可以抑制糖尿病心肌中chymanse依赖性AngⅡ的生成,起到对糖尿病心肌病变的保护作用。

Electron microscopic morphometry of heart samples revealed typical diabetic alterations consisting that myofibril arranged disordly, mitochondril swelling, mitochondrial crista and breaking and solving to form the lysis of cistae; some glycogen and lipid droplet depositing in myofibril.

模型组心肌细胞肌原纤维排列紊乱、断裂、溶解,线粒体肿胀变性,线粒体嵴断裂、溶解,形成空白区,肌细胞中可见糖原脂滴沉着;与模型组比较,TXS组心肌细胞肌原纤维排列整齐,线粒体形态尚可,偶有线粒体外膜缺损。

In our study, we also observed the different influence between TTB-USA and RFCA on blood coagulable states (by examining the change ofα-granule membrane protein、Tissue type plasminogen activatior、Plasmingen activator inhibitor-1)、 endothelium function (by examining the change of endothelin、nitric oxide) and myocardial injury (by examining the change of creatine kinase、MB isoenzy of creatine kinase and cardiac troponin T).

为观察超声消融与射频消融对血凝状态、内皮功能及心肌损伤的影响,进一步对超声消融的安全性进行评价,我们在插管前、插管后、消融后即刻、消融后30min及48小时5次抽静脉血,分别测定血小板α-颗粒糖蛋白(GMP-140)阳性表达活化血小板百分率、内皮素、一氧化氮、组织型纤溶酶原激活剂及纤溶酶原激活剂抑制物-1(PAI-1)的变化;于消融前、消融后即刻、2hr、8hr、24hr、48hr、72hr抽取静脉血,检测肌酸激酶、肌酸激酶MB同工酶及心肌肌钙蛋白T的变化。

MPG has the actions of enhancing myocardial contraction, improving myocardial compliancy and left ventricular systolic and diostolic function and increasing cardiac output and arterial blood pressure in heart failure cats caused by Pentobarbital sodium.These show MPG is beneficial to releasing heart failure.

甲基葡萄糖苷对戊巴比妥钠诱发的实验性心衰猫具有加强心肌收缩力、改善心肌顺应性和左室舒缩功能、增加心排血量、升高动脉血压的作用。

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