心肌

The results showed: there is the apoptosis of the myocardial cells during the period of I/R. The further study showed that there is the express of Bcl-2, Bax and Fas in the model of the cultured myocardial cells which were treated with ischemia-reperfusion The express of Bax, Fas proteins increase obviously. The overexpress of Bcl-2 is weak positive which shows that there is certain relationship between the apoptosis of the myocardial cells and the higher express of Fas and the ratio descent of the Bcl-2/Bax.

结果表明：在I/R过程中确有心肌细胞凋亡现象，而且进一步研究发现在培养的心肌细胞缺血-再灌注的模型中均见Bcl-2、Bax、Fas的表达，Bax、Fas蛋白的过度表达明显增加，Bcl-2的过度表达仅呈弱阳性，表明心肌细胞的凋亡与Fas的高表达，Bcl-2/Bax的比例下调有一定的必然联系。

The cyclic variation of integrated backscatter and echo intensity of three different myocardial regions perfused by left anterior descending coronary artery, left circumflex coronary artery and right coronary artery (on the frozen frame of parasternal short-axis image,those position were approximately at the 12, 4 and 8 o'clock direction to the center of the left ventricle, respectively) were measured with HP-5500 ultrasonic system and DFY ultrasonographic quantitative analysis system.

在35例急性心肌梗死患者发病2周内，用HP-5500型超声诊断仪和DFY型超声图像定量分析诊断仪，在胸骨旁左室乳头肌短轴切面，分别测量冠状动脉左前降支、左回旋支和右冠状动脉支配区域心肌组织(分别相当于左室乳头肌短轴切面上12、4、8点的位置)的IB和EI心动周期变化幅度值，以CVIB和CVEI值≤同一切面三个不同部位中最高值的1/2作为诊断心肌梗死的标准，部分病例与冠脉造影结果对比。

objective trimetazidine has shown anti-ischemic properties to improve exercise tolerance without haemodynamic effects and direct cyto protective effect on the myocardium.however,it is not clear whether trimetazidine has beneficially effect on severe ischemic cardiomyopathy.methods 19patients（68±9）years with postnecrotic left ventricular dysfunction（ejection fraction31.7%±5.4%）were studied to examine the benefit of adding60mg a day of trimetazidine for3months to the classical therapy.the assessment included clinical evaluation,electrocardiography and echocardiography.results after adding60mg a day of trimetazidine for3months,attack of angina was relieved and dyspnea was improved（p.05）.but heart rate,systolic blood pressure,rate pressure product,ejection fraction,left ventricular volume and global wall motion index were not changed.conclusion trimetazidine seems to improve clinical status while can not change oxygen supply-to-demand ratio without adverse effects in patients on severe ischemic carˉdiomyopathy.

目的 曲美他嗪是一种新型的抗心肌缺血的药物，能够改善患者的运动耐量和心肌的直接保护作用同时并没有血流动力学效应。但目前对于严重缺血性心肌病患者的临床治疗价值还需要进一步观察。方法 19例（68±9）岁确诊为缺血性心肌病（左心室射血分数0%）的患者在常规治疗的基础上加用每日60mg曲美他嗪治疗3个月，随诊观察患者临床情况以及超声心动图指标的变化。结果 19例患者均可耐受在常规治疗基础上加用每日60mg曲美他嗪的治疗，随诊发现患者心绞痛发作明显减少，运动耐量明显改善。同时患者心率、收缩压、心率血压乘积、左心室射血分数、左心室容量以及整体室壁运动指数无明显改变。结论缺血性心肌病的患者在常规治疗基础上加用曲美他嗪是安全的，同时其能明显改善患者的临床状态，而这种作用并不改变心肌氧的供求比值。

We study longitudinal motion characteristics during isovolumic contraction , ejection , isovolumic relaxation , early relaxation , atrial systole phases in left ventricular total and regional myocardium of myocardial infarction patients with three vessels lesions by Quantitative Tissue Velocity Imaging , assess systolic and diastolic function in left ventricular regional myocardium, discuss postsystolic shortening in isovolumic relaxation phase and its clinical meanings.

目的 利用超声评价三支病变的心肌梗死患者左室整体和局部心肌在心动周期各时相的纵向运动特点，评价左室局部心肌收缩和舒张功能，探讨其在等容舒张期出现的收缩后收缩现象及临床意义。

In ischemia-reperfusion injury and acute myocardial infarction animal models,inhibition of prolyl hydroxylases has been observed to prevent deleterious remodeling and to attenuate the acute inflammatory response.

在缺血再灌注心肌损伤和急性心肌梗死的动物模型中发现，DMOG能够发挥降低大鼠的心肌重构和抑制炎症反应等保护作用。

Methods: a comprehensive analysis of 20 cases with acute left ventricular failure as the first manifestations of acute subendocardial myocardial infarction patients with a history of 20 cases and clinical characteristics, according to ECG, dynamic changes of enzymes, Killip classification of cardiac function and cardiac color report indicators of cardiac function, acute acute subendocardial myocardial infarction with acute left heart failure occurred in the characteristics and causes.

综合分析20例以急性左心衰竭为首发表现的急性心内膜下心肌梗死20例病人的病史和临床特点，根据心电图、心肌酶的动态变化、 Killip 心功能分级和心脏彩超报告的心功能指标，探讨急性急性心内膜下心肌梗死发生急性左心衰竭的特征和原因。

Background and Methods:Coronary heart disease attack induced by obstructive sleep apnea syndrome is well-documented in retrospective study,but acute myocardial infarction and malignant arrhythmia triggered in acute stage,especially in superacute stage,are less-known.

报道 3 例阻塞性睡眠呼吸暂停综合征病人，例 1 表现 OSAS 诱发心绞痛逐渐演变为急性心肌梗死，例 2 在急性心肌梗死过程中引起高度窦房、房室阻滞和心脏停搏，例 3 在急性心肌梗死基础上每有呼吸暂停发作便激发出室速和室颤。

The remaining eighteen pigs, served as three viral administered groups, underwent coronary artery ligation and received intramyocardial viral injection. rAAV- GFP group (n=6), rAAV-CD151 group (n=6) and rAAV-antiCD151 group (n=6) animals respectively received direct intra- myocardial injection of rAAV-GFP, rAAV-CD151 and rAAV-antiCD151 1×10~(12 viron particles per pig, at 10 sites correspondingly.

采用三质粒共转染法包装CD151、antiCD151和GFP重组腺相关病毒(recombinant adeno-associated virus，rAAV)。2.1月龄小型猪22头，随机分为4组，分别为正常对照组4头(不予冠脉结扎和注射病毒，正常喂养)，rAAV-GFP组6头结扎冠状动脉左前降支，心肌内分10点注射1×10~(12viron particles的rAAV-GFP病毒，rAAV-CD151组6头结扎冠状动脉左前降支，心肌内分10点注射1×10~(12viron particles的rAAV-CD151病毒，rAAV-antiCD151组6头结扎冠状动脉左前降支，心肌内分10点注射1×10~(12vironparticles的rAAV-antiCD151病毒。

The experiment showed:CQP can reduce lipid peroxid a injury of myocardial cell membrane,can inhibit PLA2 activity,CQP may improv e the cell membrane fluidity,may prevent the damage of cell membrane,reduce the impairment of myocardial cell.

而CQP可减轻心肌细胞膜的脂质过氧化损伤，抑制PLA 2活性，改善细胞膜流动性，保护心肌细胞膜，减轻心肌细胞损伤。

Objective To evaluate the therapeutic effect of transmyocardial laser revascularization induced by Nd:YAG laser for the experimental acute myocardial infarct in dogs using myocardial image tomograph.

目的 采用心肌灌注显像等方法评价Nd：YAG激光心肌血运重建术治疗实验性急性心肌梗死的作用。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。