心律失常

The experimental arrhythmic model was made with Aconitin in rabbits,The Ne-iguan(PC6)point was punctured to observe the influence on recovering time ofarrhythmia.

以乌头碱造成家兔实验性心律失常模型，针刺"内关"穴观察对心律失常恢复时间的影响。

The results were analyzed with the statistical software package spss10.0.results ①between two groups,there was no significant difference about the affection of age,sex and the destribution and location of aneurism on prognosis outcome(p＜0.05).however,the grading of hunt hess and fisher in group a(gos＞3) showed significantly lower than in group b(gos≤3),（p＜0.001）;② there was no significant difference in the frequency of heart rate, st elevation, st depression,t wave inversion,u wave inversion and ventricular arrhythmia(p＞0.05).the frequency of abnormal q wave, supraventricular arrhythmia and the ecg scores in group a showed significantly lower than in group b （p＜0.05,p＜0.001）;③the ecg scores was the most powerful multivariate risk stratified(ecg ≥5 vs ecg＜5; p=0.002,or=0.010,95%ci 0.001~0.173).conclusion the ecg score, a new and simple method of semi quantification, was a powerful risk predictor for patients with sah.

应用spss10.0 统计包分析结果。结果①在年龄、性别、动脉瘤生长部位影响动脉瘤性sah预后方面，两组病例无明显差异（p＞0.05）。而按sah后hunt hess分级和fisher分级，gos＞3病例的分级要明显低于gos≤3的病例的分级（p＜0.01）；②两组在心率、st段抬高、st段压低、t波倒置、u波倒置、室性心律失常出现的频率无明显差异（p＞0.05）；在异常q波和室上性心律失常出现频率及心电图评分方面，gos＞3的组别明显低于对照组（p＜0.05，p＜0.001）；③心电图评分是sah患者预后最显著影响的变量（p=0.002，or=0.010，95%的可信区间0.001~0.173）。结论心电图评分作为一种新型、简便的半定量方法，能有效的预测蛛网膜下腔出血病人的预后。关键词：心电图；预后；评分；蛛网膜下腔出血

Treatment group (32 cases) was treated with Ginseng - Ophiopogon lnjection and common antiar- rhythmic, while control group (18 cases) with energy mixture and common antiarrhythmic.

将急性病毒性心肌炎患者50例分为两组，治疗组32例，给予参麦注射液及一般抗心律失常药；对照组18例，给予能量合剂及一般抗心律失常药，均治疗12天。

Methods Arrhythmic models induced by CaCl2 in rats were used to study the effect of DGKL on experimental arrhythmia.

方法采用氯化钙诱导的大鼠心律失常模型，观察当归颗粒对抗实验性心律失常的预防保护作用。

Methods:The arrhythmic models induced by BaCl2 in rats were used to observe the preventive effects of F2 on experimental arrhythmia.

采用氯化钡(BaCl2)诱导的心律失常大鼠模型，观察F2对实验性心律失常的预防作用。

Results Lorcainide at concentration of 0.62mg/L,1.25mg/L and 2.50mg/L had a tendency of decreasing the incidence of arrhythmia during ischemia (P＞0.05),and at 1.25mg/L and 2.50mg/L significantly decreased incidence of arrhythmia during early reperfusion (P＜0.05).Its antiarrhythmic effect was accompanied with elevation of subendocardial threshold,significant abbreviation of action potential duratin in subendocardium and subepicardium,and complete or partly delay of transmural conduction time of pulses.

结果 劳卡胺分别在0.62mg/L、1.25mg/L及2.50mg/L剂量时使缺血性心律失常发生率轻度降低(P＞0.05)，后2种剂量使再灌注早期心律失常发生率明显降低(P＜0.05)；降低心律失常发生率同时可提高心内膜下心室肌兴奋阈，延长心内、外膜下心室肌细胞动作电位时程，延迟或部分延迟冲动跨壁传导时间。

A pure and single K+ current of ultrarapid delayed rectifier K+ current or transient outware K+ current is respectively expressed on Xenopus Oocytes. This is a moderm pharmacological model for evaluation class Ⅲ antiarrhythmiv durgs, overcomes many defcts such as lacking human fresh cardiac muscle cells as material and co-expression of many currents on cell membrane. A new compound A1998 from Ocean material is evaluated in this model for class Ⅲ antiarrhythmic functions.

5和Kv4.2cDNA转录为mRNA，然后将其分别注入蟾蜍卵母细胞上：在蟾蜍卵母细胞上分别获得纯净、单一的超速延迟性整流钾电流(Ikur，ultrarapid delayed rectifier K+current)和瞬间外向钾电流(Ito，transient outward K+current)表达，克服以往在筛选评价抗心律失常药物时，人新鲜心肌细胞取材困难、多种电流在细胞膜表面共同表达等缺点，从而建立评价Ⅲ类抗心律失常药物的先进药理模型，并筛选具有Ⅲ类抗心律失常药理作用的新化合物A1998。

Grain of pace long metacentre fights the Chinese traditional medicine with wrong rhythm of the heart as group square, special research began 1987, the scientific research that becomes national form very quickly tackles key problem project.

由于西药在治疗心律失常过程中存在的不良反应，以及不尽如人意的总有效率较低30%～60%，使更多人关注深入发掘中药的抗心律失常功能上，寻找平安有效的抗心律失常中药制剂成为近年来研发者致力的重点。

This paper summarizes the clinical application of treating bradyarrhythmia with the decoction of Ephedra, Aconite and Asarum in recent ten years. It deeply clarifies that many chronic arrhythmias can be treated by the decoction of Ephedra, Aconite and Asarum from researching the treatment results of sinus bradycardia, atrioventricular block, sick sinus syndrome and slow-type arrhythmia, and the results are good.

综述了近10年来麻黄附子细辛汤在临床上治疗慢性心律失常的应用，从窦性心动过缓、房室传导阻滞、病态起搏窦房结综合征及缓慢型心律失常这几种疾病入手，深入阐明并揭示了麻黄附子细辛汤可在临床治疗多种慢性心律失常，并取得很好的疗效。

METHODS Experimental arrhythmias were induced by strophanthin G infusion through jugular vein in guinea-pigs and by myocardial ischemia-reperfusion in rats respectively. Cytosolic calcium concentration [Ca(superscript 2+] of isolated guinea-pig ventricular myocytes was examined with laser confocal scanning microscope.

采用静脉灌流毒毛花苷G诱发豚鼠心律失常，心肌缺血再灌注诱发大鼠心律失常，观察双苯氟嗪的抗心律失常作用；利用激光共聚焦扫描显微镜观察双苯氟嗪对心室肌细胞内游离钙子浓度[Ca

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。