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In it, John Hohneker, MD, vice president, US clinical development and medical affairs in the oncology division at Novartis, notes that supplemental data available on the Nature Medicine Web site indicates that all of the patients who suffered cardiotoxic side effects from the drug had NYHA class 1 functioning and normal left ventricular ejection fractions.

信中提到,我们藉此提供您有关Gleevec和自然医学线上版的一篇近来受到媒体关注的文章的讯息;信中,Novartis肿瘤部门之美国临床发展与医疗事务副总裁John Hohneker医师指出,因此药所致之心脏毒性副作用是属于NYHA class 1且仍有正常左心室射出分率,相关资料可在自然医学网站上获得;些病患数本来就有类似状况,如高血压、糖尿病和冠状动脉疾病。

The incidence rates and duration of ventricular dilation-induced arrhythmias in each of verapamil, chelerythrine or glibenclamide group were similar to those in control group. Conclusion Ventricular dilation may induce arrhythmias in isolated rat hearts, which is inhibited by ischemic preconditioning. The transient increase in [Ca(superscript 2+)] appeared to be a triggering factor in the process of ischemic preconditioning. K channel PKC might also play an important roles in this process.

对大鼠心室进行膨胀可诱发心律失常;缺血预适应对心律失常的发生具有抑制作用;细胞内钙离子浓度的短暂升高可能是缺血预适应发挥抑制作用的驱动因子;ATP敏感性钾通道及蛋白激酶C在缺血预适应过程中可能发挥了重要作用。

These techniques were effective in"minimally invasive"decannulation of ventricular assistance device with the results of no shunt and/or bleeding and satisfactory maximal flow rate.

由此建立的四种新型心室辅助实验不仅能够获得满意的最大流量,而且还可有效地完成从体外闭合体内的插管处,使之无分流和/或不出血,从而实现&微创&拔管。

However, correct decision is affected by a lot of factors. If cardiac surgeons' worries on repeat sternotomy for decannulation was appropriately resolved, the ventricular assisted circulation may get better results.

然而有许多因素制约着做出正确选择,其中重要的一个就是心脏外科医生对术后再次开胸拔管的顾虑,如果能够妥善地解决这个问题,将有助于心室辅助取得更好的结果。

The Second Affiliated Hospital, Medical School of Xian Jiaotong University, Xian 710004, ChinaABSTRACT: Objective To observe the acute homodynamic changes of biventricular pacing in patients with sick sinus syndrome and investigate the Ca2+ changes during absolute refractory period electrical stimulation by applying computer simulation.

目的 观察双心室起搏对病态窦房结综合征(sick sinus syndrome, SSS)患者的急性血液动力学变化及心脏绝对不应期电刺激对心功能的影响,通过计算机仿真研究,探讨绝对不应期电刺激的离子流作用机制。

The patient's vital sign was stable intraoperative and cardiologist was consulted after he was transferred to ward. The 12 lead ECG showed complete AV block and diffuse ST-segment elevation. The echocardiogram showed LV global hypokinesia with impaired contractility, ejection fraction 37% and dilated right heart.

手术中病患的生命徵象都稳定,术后回到病房即照会心脏科医师。12导程心电图显示为完全性房室阻断及广泛的ST升高;心脏超音波检查发现左心室跳动不良、收缩力不好,射出率只有37%,右心有扩大的现象。

Objective To design and develop a magnetically drived axial left ventricular assist device, and evaluate its performance.

目的 对研制开发的一种新型的磁力外驱动轴流式心室辅助血泵的血液相容性能进行测试。

This purpose of design is a computer simulation ventricle except that electric vector quantity of the heart surrounds the running orbit very much, through the stereoscopic and dynamic way, show the course that the vectorial ring of electricity of heart forms, can make student image, understand electric vector quantity of the heart ocularly; Type the well practical foundation in order to study the kind electric picture.

本设计目的是计算机模拟心室除极心电向量环运行轨迹,通过立体动态的方式,展示心电向量环形成的过程,使学生能够更形象,直观地理解心电向量;为学好心电图打好切实的基础。

Cardiac hypertrophy and extracellular matrix remodeling happened as a result of chronic overrange of pressure in heart and hypervolaemia which lead to damage of relaxation and compliance of heart.Drugs including renin-angiotensin converting enzyme inhibitor,angiotensin receptor blocker,aderergic receptor blocker,aldrosteron antagonism,tatins endothelin receptor blocker pancreatic kiniogenase and calcalium channel blocker,can delay or reverse the remodeling by several mechanisms.

主要表现为心脏在慢性超负荷的压力、容量作用下发生的病理改变致使左室肥厚组织胶原结构发生改变,导致心肌顺应性降低,舒张功能受到损害;作用于肾素-血管紧张素系统的药物及肾上腺素受体阻滞剂、醛固酮拮抗剂、他汀类药物、内皮素受体拮抗剂、胰激肽原酶、钙通道阻滞剂等药物通过不同途径和机制延缓和逆转左心室重构。

The left ventricle ponderal index (92.35±19. 03) and LVEF [ (50. 14±7. 23)%] of GH low level group were lower than those of normal level group (P. 05 all). Conclusion; There is significant influence of GH on aged cardiovascular system. Growth hormone ; Cardiovascular system ; Aged

本研究对老年人血液生长激素水平和心室壁厚度以及心脏射血分数的关系进行分析,探讨生长激素水平对心功能的影响。1资料与方法1.1一般资料研究对象均为1999~2001年我院住院的患者,男72

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。