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The technology of error compensation based on Multi-Body system and the design method of cam machining were combined together.

针对精密凸轮加工中存在的精度问题,推导出凸轮磨削中的理想砂轮中心包络线的求解方程,进而将基于多体系统理论的误差补偿技术与凸轮加工设计方法相结合,研究了理想数控指令的生成方法、砂轮轮廓误差的计算方法、精密数控指令和逆变凸轮廓型的求解算法,在此基础上,开发出凸轮精密磨削过程的误差补偿与动态仿真分析软件。

Other Less Common Symptoms: A whole cluster of other symptoms appear during this infection, including progressive loss of hearing : that is, a gradually increasing deafness in older people (probably sensorineural hearing loss ); in younger people, a subtle loss of hearing acuity is noticed, meaning that it becomes a little more difficult to identifying environmental sounds, and more difficult to sensing their exact location; increased tinnitus ; sense of balance becoming noticeably less acute; dizziness spells; hoarse voice due to persistent throat soreness,(or possibly due to connective tissue damage in the larynx); chronic white tongue coating (called geographic tongue or migratory glossitis); red eyes (mild conjunctivitis, aka: pinkeye); infection of the urethra ; viral headache; eczema / psoriasis; large area of red greasy skin on the chest, just below the neck; increased hair loss; cold hands and feet; slow wound healing; weight gain on stomach; kidney pains ; joint pains; muscle cramps , especially in the calf muscles; sudden episodes of racing heart and heart palpitations; acute pericarditis; aseptic meningitis; reduced attention and concentration; forgetting words, losing some of your vocabulary, suddenly having more difficulty in spelling words and remembering information; frequently selecting incorrect words while talking (and strangely, sometimes selecting a word which is incorrect, but from the same category as the right word for example, saying "pun" when you meant to say "irony" both are in the same category of literary devices).

其他较常见的症状:对整个集群等症状出现在这个感染,包括听力逐渐丧失,即:在老年人耳聋逐渐增加(可能是神经性听力损失),在年轻人,一个微妙的听力丧失视力注意到,这意味着它变得有点更加难以确定的环境声音,更难以检测他们的确切位置,增加耳鸣,平衡感越来越明显那么尖锐,头晕法术;嘶哑的声音,由于持续的咽喉疼痛,(或可能是由于在喉部结缔组织损害),慢性白苔,红色的眼睛(轻度结膜炎,又名:火眼),尿道感染,病毒性头痛,湿疹/牛皮癣,大面积红油腻皮肤的胸部,颈部下方,增加脱发;手脚冰冷,伤口愈合缓慢,体重在胃增益;肾痛苦;,关节痛,肌肉痉挛,特别是在小腿肌肉,突然心脏病发作的赛车和心悸,急性心包炎,无菌性脑膜炎;减少,注意力和集中力,忘记的话,失去的一些词汇,突然有更多的拼写字和困难记住信息;经常选择不正确的话,而谈话(和奇怪的是,有时一个单词的选择是不正确的,但是从文字的权利-例如同一类,称"双关"当你的意思是说"讽刺"-无论是在文学设备同一类)。

CaN Aβ gene silencing can reduce myocardial hypertrophy in cultured cells, si1280 (21bp) of CaN Aβ gene is the most effective target site for siRNA. The method of intrapericardial injection of plasmid, microbubbles and erzymes can improve transfection efficiency of non-viral plasmid with satisfying targeted transfection. But the scope of transfected myocytes is still limited. CaN Aβ shRNA expressing plasmid transfection in vivo by pericardial injection results in decreased CaN Aβ protein expression of small part of myocytes, and CaN Aβ mRNA only shows decreased trend. The dosage of non-viral vector and the parameters of ultrasound energy should be optimized in further study.

结论RNAi技术抑制CaN Aβ基因表达可有效减轻Ald诱导的心肌细胞肥大程度;CaN Aβ基因中si1280(21bp)片段为实现RNAi的更有效片段;微泡+酶类心包腔内注射超声导入的方法可有效改善非病毒载体在体心肌的转染效率,同时具有一定的靶向性,但总的转染范围仍然有限;采用这一方法进一步进行&一肾一夹&心肌肥大模型大鼠在体心肌细胞的CaNAβ的RNAi干预,发现心肌肥大大鼠心外膜下局部心肌细胞CaN Aβ蛋白水平降低,CaN AβmRNA水平虽有下降趋势,但无统计学差异,提示质粒的用量及超声导入的参数有待进一步研究使其优化。

Later, under the untypical parasternal four-chamber view which can thoroughly display the ostium of coronary sinus, the catheter was promoted further to the ostium of coronary venous sinus. Then the echocardiography technician adjusted the transducer of TTE in order to thoroughly confirm the position of the catheter tip. After confirming the position of catheter tip in the coronary venous sinus, the operator inserted the catheter into the coronary venous sinus for 3~4 mm farther. It was noted that if resistance was encountered by operator, the operation must be stopped, which was the same as x-ray fluroscopy as image guiding. TTE guiding His bundle elactric cahteter、high right atrium electric cahteter and right ventricular electric catheter in site: It is difficult using TTE singly since there are too many crossroads in inferior venous.

本研究结果显示,(1)单独应用TTE作为影像学引导进行冠状窦电极导管置放的成功率为93.8%~96.7%,并且应用TTE作为影像学引导放置专用冠状窦电极导管和普通电极导管的成功率和放置时间在统计学上无显著差异;(2)TTE作为影像学引导,除过度肥胖患者外,可完全替代X线引导进行冠状窦电极导管置放,包括鞘管和扩张管的放置、指引导丝在静脉而非动脉内的证实均可由TTE完成引导,且较X线C型臂有一定优越性;(3)TTE结合普通X线胃肠透视机作为影像学导引,可顺利完成心内电生理检查时导管的安全到位,而不需昂贵的X线C型臂,可将心内电生理检查扩大到广大的基层医院;(4)TTE较X线更易和更早期发现介入治疗的并发症如急性心包填塞等,对并发症的防治甚至挽救病人的生命至为重要;(5)动物实验研究表明,TEE可引导射频导管消融术时大头电极导管成功到位。

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This paper discusses design and realizable methods of remote test output interface from logical design angle.

本文从逻辑设计的角度讨论遥测输出接口的设计及实现方法。

This also 星体投射plies to buildings, structures and geological features.

这也适用于建筑物和地质特征。

We all hope for a better life.

我们都希望好的生活。