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Intrapericardial total pneumonectomy is safe,it can raise the pulmonary resection rate and prolong the survival period of the patients.

心包内处理肺血管全肺切除术安全性较好,可提高肺癌切除率、延长术后生存期。

CaN Aβ gene silencing can reduce myocardial hypertrophy in cultured cells, si1280 (21bp) of CaN Aβ gene is the most effective target site for siRNA. The method of intrapericardial injection of plasmid, microbubbles and erzymes can improve transfection efficiency of non-viral plasmid with satisfying targeted transfection. But the scope of transfected myocytes is still limited. CaN Aβ shRNA expressing plasmid transfection in vivo by pericardial injection results in decreased CaN Aβ protein expression of small part of myocytes, and CaN Aβ mRNA only shows decreased trend. The dosage of non-viral vector and the parameters of ultrasound energy should be optimized in further study.

结论RNAi技术抑制CaN Aβ基因表达可有效减轻Ald诱导的心肌细胞肥大程度;CaN Aβ基因中si1280(21bp)片段为实现RNAi的更有效片段;微泡+酶类心包腔内注射超声导入的方法可有效改善非病毒载体在体心肌的转染效率,同时具有一定的靶向性,但总的转染范围仍然有限;采用这一方法进一步进行&一肾一夹&心肌肥大模型大鼠在体心肌细胞的CaNAβ的RNAi干预,发现心肌肥大大鼠心外膜下局部心肌细胞CaN Aβ蛋白水平降低,CaN AβmRNA水平虽有下降趋势,但无统计学差异,提示质粒的用量及超声导入的参数有待进一步研究使其优化。

Immunofluorescence staining shows that, the CaN Aβ protein expression of intrapericardial injection group decreased in some myocytes under epicardium, while other groups show no decreased fluorescence.

三在体心肌CaN AβsiRNA表达质粒转染后,转染各组与心肌肥大模型组CaN AβmRNA水平比较无差异(P>0.05),但免疫荧光结果显示心包腔内途径CaN Aβ干扰组较心肌肥大模型组心外膜下部分心肌荧光减弱。

The layer of flat cells of mesodermal origin that lines the embryonic body cavity and gives rise to the squamous cells of the peritoneum, pericardium, and pleura .

间皮起源于中胚层的扁平细胞层,衬于胚胎的原始体腔中,最终发育成腹膜、心包及胸膜的上皮细胞

Objective To evaluate pericardial endothelin secretion by the human pericardial mesothelial cells.

目的 探讨人心包间皮细胞能否分泌内皮素。

Objective:To evaluate the role of magnetic resonance imagingin the diagnosis of non myxomatous primary tumors of the heart and pericardium.

目的 :分析心脏心包非粘液瘤性原发性肿瘤磁共振成像的影像学特征,评估其临床价值。

Methods:The magnetic resonancestudies were performed in the 14 patients with non myxomatous cardiac and pericardial tumors with the spin echo and cine pulse sequence.

收集经手术病理证实的原发性非粘液瘤性心脏心包肿瘤 14例,行 MRI自旋回波多体位扫描及磁共振电影检查。

Results:The reasons of unresectable 131 lung cancer were: metastasis in the thoracic cavity, freezing of hilum of lung, neoplasma encroach the main organs of mediastinum, and could not tolerate the extended resection because of the limitation of pulmonary function.

结果:131例肺癌不能切除的原因依次为:胸腔内多发转移,&肺门冻结&经打开心包仍不能处理血管,肿瘤侵犯纵隔内重要结构,以及肺功能受限不能耐受扩大切除范围等。1992年~2006年的探查率为8.1%(66/813),较1985~1991年的15.6%(65/417)有明显下降。

Changes in Red Cell Enzyme Activity in Relation to Red Cell Survival in Infancy Antibody Deficiency Syndrome with Increased Gamma1 M(B2M) Globulins and Absent Gamma1 A(B2A) Globulins and Gamma2 Globulins. Needle Biopsy of the Liver in Various Forms of Childhood Tuberculosis Jaundice Associated with Severe Bacterial Infection in Young Infants Effectt of Hypoxia on Newborn Animals Renal Amyloidosis Resulting From a Chronically Infected Burn. Skin Testing of Allergic and Normal Children with Purified Milk Proteins. Pericarditis in Juvenile Rheumatoid Arthritis Cardiac Complication of Diphtheria Adenovirus Complement-fixing Titers from Birth through First Year Congenital Coronary A-V Fistula Narcotic and Methamphetamine Use During Pregnancy Purulent Pericarditis Transfer of Bilirubin-C^4 Across Monkey Placenta Plasma Antidiuretic Hormone in Nephrogenic Diabetes Insipidus Studies of Anabolic Steroids:Ⅰ.

红血球酵素活性度之变化与婴儿红血球生存期之关系 Gamma1 M(B2M)球蛋白增加而无Gamma1 A(B2A)球蛋白与Gamma2球蛋白之抗体缺乏症候羣儿童期各型结核病之肝藏针管活体切片检查幼儿细菌严重感染并发之黄疸缺氧对於新生动物之影响及其与肺玻璃膜病之关系烧伤处慢性感染引起之肾性淀粉样变性以精制奶粉蛋白对过敏症与正常小儿作皮肤试验年幼性类风湿性关节为合并的心包炎白喉之心脏合并症自出生至一岁之腺病毒补体结合滴定度先天性冠状动静脉瘻管怀孕时使用麻醉剂与Methamphetamine之结果化脓性心囊炎胆红素C^14标猴子胎盘之转送肾因性尿崩症患儿之血清抗利尿荷尔蒙之证明同化类固醇之研究Ⅰ。

Later, under the untypical parasternal four-chamber view which can thoroughly display the ostium of coronary sinus, the catheter was promoted further to the ostium of coronary venous sinus. Then the echocardiography technician adjusted the transducer of TTE in order to thoroughly confirm the position of the catheter tip. After confirming the position of catheter tip in the coronary venous sinus, the operator inserted the catheter into the coronary venous sinus for 3~4 mm farther. It was noted that if resistance was encountered by operator, the operation must be stopped, which was the same as x-ray fluroscopy as image guiding. TTE guiding His bundle elactric cahteter、high right atrium electric cahteter and right ventricular electric catheter in site: It is difficult using TTE singly since there are too many crossroads in inferior venous.

本研究结果显示,(1)单独应用TTE作为影像学引导进行冠状窦电极导管置放的成功率为93.8%~96.7%,并且应用TTE作为影像学引导放置专用冠状窦电极导管和普通电极导管的成功率和放置时间在统计学上无显著差异;(2)TTE作为影像学引导,除过度肥胖患者外,可完全替代X线引导进行冠状窦电极导管置放,包括鞘管和扩张管的放置、指引导丝在静脉而非动脉内的证实均可由TTE完成引导,且较X线C型臂有一定优越性;(3)TTE结合普通X线胃肠透视机作为影像学导引,可顺利完成心内电生理检查时导管的安全到位,而不需昂贵的X线C型臂,可将心内电生理检查扩大到广大的基层医院;(4)TTE较X线更易和更早期发现介入治疗的并发症如急性心包填塞等,对并发症的防治甚至挽救病人的生命至为重要;(5)动物实验研究表明,TEE可引导射频导管消融术时大头电极导管成功到位。

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