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In order to study the relation of cytochrome P-450 with the protective action of SY-801 and SY-640 against 〓-induced UDS and 3H-BP binding to nuclear DNA, the effects of SY-801 and SY-640 on liver microsomal cytochrome P-450 were studied in mice. The results indicated that the liver microsomal cytochrome P-450 concentration and aminopyrine demethylase activity were significantly increased in mice pretreated with SY-801 150mg/kg or SY-640 150 mg/kg once daily for three days.

本实验进而观察了SY-801对小鼠肝微粒体细胞色素P-450酶系的影响,结果表明SY-801和SY-640体内连续给药3天,可诱导小鼠肝微粒体细胞色素P-450含量明显增加,同时氨基比林脱甲基酶活性亦明显增加;给药1次2小时内二者均可抑制氨基比林脱甲基酶活性,而对肝微粒体细胞色素P-450含量则无明显影响。

The induction periods and particulate fouling asymptotic resistances of arc line tube were obtained by comparative experiment under various particulate concentration and liquid velocity. The flow field and shear stress in the arc line tube were numerically simulated and analyzed.

文中通过不同流速和微粒浓度下微粒污垢的加速实验,得到了弧线管微粒污垢渐近热阻值和诱导期;同时,用数值方法模拟了弧线管的内部流场和壁面剪切力。

Introduce the ideological root causes and background knowledge in detailed, give the iterative formula and the iteration step.

针对微粒群算法在求解函数优化问题时出现的一系列问题,本文提出了雁群算法,详细介绍了雁群算法的提出的思想根源和背景知识,给出了算法的迭代公式和迭代步骤,并结合具体实例与微粒群算法相比较,对于某些优化问题,其优化性能比微粒群算法有较大的提高,在一定程度上弥补了微粒群算法的不足。

The size effect on metastability of Co particles was discussed based on the influence of the surface tension on the martensitic transformation.

根据表面附加压应力对微粒马氏体相变的影响,探讨了微粒尺寸对Co微粒亚稳结构稳定性的影响。

The weight and protein content of the microsomes from different evolutionary animal and tissue cells were first determined, and the weight of microsome varies obviously and the protein content of microsome in unit is almost the same.

本文还首次系统比较了不同组织细胞和不同进化程度动物细胞的微粒体获得率及蛋白含量,得到了不同细胞微粒体获得率明显不同、单位重量微粒体蛋白含量却基本相同的结果,表明不同细胞ER含量不同,而单位ER内蛋白含量基本相同。

We employed HPLC to measure the metabolites of caffeine in the whole blood and calculated the ratio be between the metabolite and caffeine, which was used as index to evaluate the effect of Qingkailing injection on rat CYP1A2 activity in vivo ; We also detected the CYP1A2 and CYP2D6 activity in microsomal reconstituted system by analysis of phenacetin metabolism and dextromethorphan metabolism with HPLC.

通过HPLC法测定全血中咖啡因的代谢率,观测清开灵注射液对大鼠CYP1A2活性的影响;通过HPLC法测定大鼠肝微粒体重组系统非那西丁的代谢比率,确定清开灵注射液对大鼠肝微粒体CYP1A2亚型的作用;测定大鼠肝微粒体重组系统右美沙芬的代谢比率,确定清开灵注射液对大鼠肝微粒体CYP2D6亚型的作用。

A Multi-Species Cooperative PSO algorithm is developed using the ideas of species dividing in the bionomical world. The algorithm is shown to have guaranteed convergence to the global optimum. Furthermore, the training strategies of RBF network structures and weights based on the MCPSO aigorithm is proposed. Simulation results show that the algorithm is effective in such fields as chaotic time-sequence forecasting, system identification, speech signal processing and etc.

在分析基本微粒群算法和协同微粒群算法特点的基础上,借鉴生态学中的种群划分思想,设计出一种多种群协同进化微粒群算法,并分析了该算法的收敛性能;在分析径向基函数神经网络结构的基础上,提出了基于多种群协同进化微粒群算法的径向基函数神经网络结构和权值优化设计策略,并在混沌序列预测、系统辨识、语音信号处理等应用仿真实验中验证了算法的有效性。

Organic and compound cation garrulous coagulates the agent is to use chemical law compound a kind of new-style cation garrulous coagulates agent, belong to domestic and international initiate, with other and groovy drug photograph comparing has 5 big advantages: The photograph such as aluminium of as aggregate as commonly used drug chloridize, aggregate and vitriolic iron, vitriolic aluminium is compared, coagulate with garrulous of polypropylene acyl amine the agent is used jointly, medical dose is little, reduce useless water treatment to expend about 20 % thereby, 30 %; Effect of processing liquid waste is good, garrulous is round settling speed is fast, make liquid waste can second birth is used, managing water natural resources; Its garrulous group is sedimentary filterability can be good, slime can reclaim inside entire plant, namely energy-saving be helpful for protecting an environment again; Corrode to equipment small; Have muti_function, have agglomeration effect already, again garrulous coagulates action and the action that aid filter, can serve as filter aid.内容来自www.ch-water.com

有机复合阳离子絮凝(使液体中悬浮微粒集聚变大或形成絮团,从而加快粒子聚沉,达到固-液分离的过程)剂是利用化学法合成的一种新型阳离子絮凝(使液体中悬浮微粒集聚变大或形成絮团,从而加快粒子聚沉,达到固-液分离的过程)剂,属国内外首创,与其他常规药剂相比具有五大优点:与常用药剂聚合氯化铝、聚合硫酸铁、硫酸铝等相比,与聚丙烯酰胺类絮凝(使液体中悬浮微粒集聚变大或形成絮团,从而加快粒子聚沉,达到固-液分离的过程)剂联合使用,药剂量少,从而降低废水处理(通过物化方法去除水中一些物质的过程)费约20%—30%;处理废水效果好,絮团沉降速度快,使废水能再生利用,节约水资源;其絮团沉渣过滤性能好,煤泥可全部厂内回收,即节能又有利于保护环境;对设备腐蚀小;具有多功能,既有凝聚作用,又有絮凝(使液体中悬浮微粒集聚变大或形成絮团,从而加快粒子聚沉,达到固-液分离的过程)作用和助滤作用,可作为助滤剂。

At concentration of 2% PEG8000, 30% microsomal protein containing 10% of total P450 was precipitated. At concentration of 5% PEG8000, 55% microsomal protein containing 20% of total P450 was precipitated. At concentration of 8% PEG8000, 78% microsomal protein containing 30% of total P450 was precipitated. At concentration of 11% PEG8000, 85% microsomal protein containing 70% of total P450 was precipitated.

当PEG的浓度为2%时,约30%的微粒体蛋白和10%的P450被沉淀;PEG为5%时,约55%的微粒体蛋白和20%的P450被沉淀;PEG为8%时,约78%的微粒体蛋白和30%的P450被沉淀;PEG为11%时,约85%的微粒体蛋白和70%的P450被沉淀。

The technique of liver CYP450 enzymes was applied to the in vitro study of drug metabolism In the first part of this article, the metabolism of nimodipine in human liver microsomes was studied and in the second of part of this article the metabolism of clivorine in female rat, guinea pig, human liver microsomes as well as the mechanism of metabolism-induced toxicity were investigated.

运用肝微粒体技术进行药物的体外代谢研究。本论文第一部分运用肝微粒体技术研究了尼莫地平在人肝微粒体内的代谢及其代谢的酶动力学,第二部分研究了肝毒性生物碱Clivorine在大鼠、豚鼠和人肝微粒体内的代谢及其代谢致毒机理。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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