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Positive results of mutagenicity have been obtained with chrysophanol aloe-emodin emodin and chrysarobin in Salmonella /microsome assays.

致畸作用。沙门氏菌/微粒体中的致畸结果为阳性的有:大黄酚,芦荟-大黄素,大黄素,和驱虫豆素以上均为大黄的化学成份),大黄酸的结果为阴性。

The microsome was extracted from human thyroid tissue by means of gradient centri-fugation in presence of sucrose.

本试验以梯度离心的方法,从存有蔗糖液的人甲状腺组织匀浆中提取微粒体,经洗涤后去除甲状腺细胞中的杂蛋白,特别是甲状腺球蛋白成份。

Methods: The health adult human primary hepatocyte microsome was randomly divided into 12 groups for control and itraconazole with different concentrations in the range of clinical drug blood concentration, each group have 10 samples. Control groups were added culture fluid, itraconazole groups were added itraconazole with different concentration respectively, after cultured 30 minutes, substrates (phenacetin for CYP1A2, testosterone for CYP3A4) were added and cultured for another 40 minutes.

采用健康成人肝细胞微粒体,分为对照组和不同浓度的伊曲康唑组,共12组,每组10个样本,伊曲康唑组分别加入血药浓度范围内不同对应浓度的伊曲康唑,对照组仅加入培养液,孵育30 min后,再加入CYP450同工酶1A2和3A4的相应底物再孵育40 min。

The vector sum of the angular momentums of each component particle of an extended body.

动量矩伸展体的每个组成微粒的角动量的矢量值。

In the present series of studies, we explored individual and ethnic differences in the activity and content of several CYP forms important to drug metabolism in three Chinese ethnic groups by using in vitro methods.

在本系列研究中,应用体外方法,我们在中国3个种群的肝微粒体中,对几种在药物代谢中具有重要地位的CYP探讨了其活性和含量的个体及种族差异。

As to the increasing of the contents of LPO in hepatic mitochondrial and microsomal, CAT and FIS do have good inhibitive effects.

同时,对铁超载引起的肝线粒体和微粒体中LPO含量的增加,CAT和FIS也有很好的抑制作用。

In present study, we observed effect of taurine on liver lipid metabolism in rat, an animal capable of synthesizing substantial amount of taurine and extensively used in studies on lipid metabolism, and tried to explain its biochemical basis by investigating several hepatic microsomal membrane-bound enzymes activities related to lipid metabolism.

本实验中,我们将观察牛磺酸对大鼠肝脂质代谢的影响,并观察牛磺酸对大鼠肝脏微粒体脂质代谢酶活力的影响,以探讨牛磺酸影响肝脏脂质代谢的可能机制。

The in vitro biotransformation of 6-CH3-HBP and 6-OH-HBP by rat liver microsomes was investigated by the developed GC/MS method.

利用已经建立的研究正丁苯酞体外代谢转化的GC/MS方法,进行了甲氧基、羟基取代丁苯酞在大鼠肝微粒体中的代谢转化研究。

Here we describe a method for the efficient extraction of proteins from rat liver microsomes, using Pressure Cycling Technology and the novel chemistry of the Kit. ProteoSolve

本文描述了一种有效的从大鼠肝脏微粒体中提取蛋白的方法,该方法正是利用压力循环技术和一种特别的ProteoSolve试剂盒。

ResultsCXNT (2, 4, 8 mg/mL) metobolized by rat liver microsomes could all inhibite the proliferation of GMC and production of IL-6 and ET-1 in a dose-dependent manner.

结果经肝微粒体代谢后,复方血尿停2、4、8mg/mL均抑制GMC的增殖及IL-6、ET-1的产生,且呈剂量依赖方式。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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