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This study established a LC-MS/MS method for the determination of squamocin and bullatacin, and calculated their enzyme kinetics in rat microsome.

[目的]建立番荔枝内酯类化合物squamocin和bullatacin的液相色谱串联质谱检测方法,并测定其在大鼠肝微粒体中的酶动力学参数。

METHODS: Using phenacetin as a substrate probe, the effects of Wuji Pill with different compatibility (No.1-9) on the enzymatic activity of CYP1A2 were detected by high-performance liquid chromatography.

按L9(34)正交表,戊己丸的配比设计为9个受试复方,以非那西丁为探针药, HPLC检测戊己丸对大鼠体外肝微粒体CYP1A2酶活性的影响。

CPZ and TFP inhibited ethylene-induced increase in activity of Ca〓-ATPase located in microsomal membrane in tomato and strawberry fruit, which indicated that 1 CaM involved in inducing of ethylene on Ca〓-ATPase; 2 the enzyme was regulated by CaM.

钙凋素拮抗剂CPZ和TFP能抑制乙烯诱导番茄果实和草莓果实微粒体膜Ca〓-ATPase活性,这表明CaM参与乙烯对该酶的诱导以及该酶活性受CaM的调节。

CYP3A4 (32%) is the most abundant CYP in Chinese liver microsomes, and the levels of CYP2C9 (19%) and CYP1A2 (16%) were also considerable.

CYP3A4(32%)是中国人肝微粒体中含量最丰富的CYP,而CYP2C9(19%)和CYP1A2(16%)的表达水平也相当可观。

The result indicated that the zircon saturation temperatures for host granodioriterange in 762~773oC,the average is 769oC,and the zircon saturation temperatures for mafic microgranular enclaves range in 752~770oC,the average is 760oC.

计算结果表明,阳坝花岗闪长岩的锆石饱和温度介于762~773oC,平均值为769oC,暗色微粒包体的锆石饱和温度介于752~770oC,平均值为760oC。

These results indicate that cabbage phenolic extract and single phenolic acids,i.e.Ferulic acid,Sinapinic acid and Gallic acid,etc.

研究表明,卷心菜提取物以及单个酚酸(儿茶素、阿魏酸和香豆酸)可以抑制〓、〓—7,8—二氢二醇和四氯化碳在肝微粒体作用下的代谢,降低主要代谢产物〓—7,8—二氢二醇、〓—7,8—二氢二醇—9,10一环氧化物和丙二醛的生成量。

In addition, our data suggest that norpregnane derivatives may be thrombogenic, whereas micronized progesterone and pregnane derivatives appear safe with respect to thrombotic risk.

另外,我们研究表明非孕烷衍生物可能具有血栓形成性,而微粒化的黄体酮和孕烷衍生物相对于血栓形成似乎是安全的。

At last,the optimized formula composition and technique of preparation were obtained by orthogonal design,and long-circulating praziquantel liposome was prepared.

在建立吡喹酮含量测定方法的基础上,通过葡聚糖凝胶柱色谱法、显微镜法、激光散射法等定性及定量方法考察脂质体的包封率、微粒外观、粒径及其分布等指标。

Phenobarbital does not impair normal hepatic function but has been shown to induce liver microsomal enzymes, thus increasing and/or altering the metabolism of barbiturates and other drugs.

苯巴比妥不损害肝脏的功能,但可诱导肝微粒体酶,从而增加或改变巴比妥类和其他药物的代谢。

Through a multidimensional compared to prove the feasibility and reliability of in vitro drug metabolism platform of human and rat liver microsomes.

通过多方面的比较,证明了本研究建立的人、鼠肝微粒体体外药物代谢平台的可行性和可靠性。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。