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Methods The activities of liver microsomal erythromycin N-demethylaseand aminopyrine N-demethylase were measured by spectrophotometry. The levels of mRNA expressions of CYP3A1, CYP1A2, CYP2E1, mdrla and mdrlb in hepatic microsome were determined with RT-PCR method.

用分光光度法测定大鼠肝微粒体红霉素N-脱甲基酶、氨基比林N-脱甲基酶的活性,用逆转录聚合酶链反应技术测定大鼠肝脏CYP3A1、CYP1A2、CYP2E1、mdr la和mdr lb基因的水平。

Mehtod: animals were given intraperitoneally normal saline(10ml/kg.d), phenobarbital (40mg/kg.d) and puerarin (100, 200mg/kg.d) respectively for seven days. Then the levels of hepatic microsomal CYP and cytochrome b5(Cytb5), and the activities of aniline hydroxylase and aminopyrine N-demethylase were determined by spectrophotography.

实验动物分别腹腔注射生理盐水、苯巴比妥(40mg/kg.d)、葛根素(100和200 mg/kg.d),给药7d后,用分光光度法测定肝微粒体CYP和细胞色素b5(Cytb5)的含量,以及苯胺羟化酶和氨基比林N-脱甲基酶的活性。

Mehtod: The animals were given intraperitoneally normal saline(10ml/kg.d), phenobarbital (40mg/kg.d) and puerarin (100, 200mg/kg.d) respectively for seven days. Then the levels of hepatic microsomal CYP and cytochrome b5(Cytb5), and the activities of aniline hydroxylase and aminopyrine N-demethylase were determined by spectrophotography.

实验动物分别腹腔注射生理盐水、苯巴比妥(40mg/kg.d)、葛根素(100和200 mg/kg.d),给药7d后,用分光光度法测定肝微粒体CYP和细胞色素b5(Cytb5)的含量,以及苯胺羟化酶和氨基比林N-脱甲基酶的活性。

Oeeki Y reported a method of partial arterialization of portal vein with ileo-colon arteriovenous anastomosis in 1997, he thought this can prevent theliver failure caused by embolism of hepatic artery after liver operation.

但过量动脉血(门静脉内动脉血灌流量达到门静脉正常血流量的一倍以上时)灌流肝内门静脉则对肝脏有害,如导致肝内门静脉分支增宽,内膜纤维变性,以及肝细胞微粒体酶活力的改变。

Results Adult worms of S. Japonicum were shown to possess important enzymes of the heme degrading system, heme oxygenase and biliverdin reductase.

结果在日本血吸虫成虫的微粒体和匀浆上清中分别检测到HO和BR,其酶的比活性分别为56.7 nmol bilirubin/和43.4 nmol bilirubin/。

Cytochrome 〓 is a membrane-bound protein and can be proteolyzed to yield a soluble domain which contain...

细胞色素〓是一种电子传递蛋白,广泛存在于生物的微粒体、线粒体及血液的红细胞中。

They act as electron-transport agents and play an important role in the electron-transport chains of respiration, photosynthesis, and the microsomal system responsible for the desaturation of fatty acids in heterotroph ic bacteria.

它们作为电子传递物在呼吸电子迁移链、光合作用及微粒体系统中起重要作用,它还负责异养细菌中脂肪酸的去饱和作用。你知道它的英文吗?

Aim of this study was to preparation of human and rat liver microsomes and determination of metabolite profile in liver.

本研究的目的是建立体外药物代谢研究用的人和鼠肝微粒体药物代谢模型,并对其应用进行初探。

The rat's testis damage is related to the enhancement of oxidative stress of mitochondria and microsome caused by nickel sulfate.

镍对大鼠睾丸细胞的损伤可能和其所致的睾丸细胞线粒体及微粒体氧化应激效应增强有关。

The incubation system of chicken hepatic microsome was successfully established. The activity of cytochrome P450 was determined by ultraviolet spectrophotometry.

在建立鸡肝微粒体体外孵育体系的基础上,采用紫外分光光度法测定细胞色素P450酶系的活性。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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