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Methods The activities of liver microsomal erythromycin N-demethylaseand aminopyrine N-demethylase were measured by spectrophotometry. The levels of mRNA expressions of CYP3A1, CYP1A2, CYP2E1, mdrla and mdrlb in hepatic microsome were determined with RT-PCR method.

用分光光度法测定大鼠肝微粒体红霉素N-脱甲基酶、氨基比林N-脱甲基酶的活性,用逆转录聚合酶链反应技术测定大鼠肝脏CYP3A1、CYP1A2、CYP2E1、mdr la和mdr lb基因的水平。

Mehtod: animals were given intraperitoneally normal saline(10ml/kg.d), phenobarbital (40mg/kg.d) and puerarin (100, 200mg/kg.d) respectively for seven days. Then the levels of hepatic microsomal CYP and cytochrome b5(Cytb5), and the activities of aniline hydroxylase and aminopyrine N-demethylase were determined by spectrophotography.

实验动物分别腹腔注射生理盐水、苯巴比妥(40mg/kg.d)、葛根素(100和200 mg/kg.d),给药7d后,用分光光度法测定肝微粒体CYP和细胞色素b5(Cytb5)的含量,以及苯胺羟化酶和氨基比林N-脱甲基酶的活性。

Mehtod: The animals were given intraperitoneally normal saline(10ml/kg.d), phenobarbital (40mg/kg.d) and puerarin (100, 200mg/kg.d) respectively for seven days. Then the levels of hepatic microsomal CYP and cytochrome b5(Cytb5), and the activities of aniline hydroxylase and aminopyrine N-demethylase were determined by spectrophotography.

实验动物分别腹腔注射生理盐水、苯巴比妥(40mg/kg.d)、葛根素(100和200 mg/kg.d),给药7d后,用分光光度法测定肝微粒体CYP和细胞色素b5(Cytb5)的含量,以及苯胺羟化酶和氨基比林N-脱甲基酶的活性。

Oeeki Y reported a method of partial arterialization of portal vein with ileo-colon arteriovenous anastomosis in 1997, he thought this can prevent theliver failure caused by embolism of hepatic artery after liver operation.

但过量动脉血(门静脉内动脉血灌流量达到门静脉正常血流量的一倍以上时)灌流肝内门静脉则对肝脏有害,如导致肝内门静脉分支增宽,内膜纤维变性,以及肝细胞微粒体酶活力的改变。

Results Adult worms of S. Japonicum were shown to possess important enzymes of the heme degrading system, heme oxygenase and biliverdin reductase.

结果在日本血吸虫成虫的微粒体和匀浆上清中分别检测到HO和BR,其酶的比活性分别为56.7 nmol bilirubin/和43.4 nmol bilirubin/。

Positive results of mutagenicity have been obtained with chrysophanol aloe-emodin emodin and chrysarobin in Salmonella /microsome assays.

致畸作用。沙门氏菌/微粒体中的致畸结果为阳性的有:大黄酚,芦荟-大黄素,大黄素,和驱虫豆素以上均为大黄的化学成份),大黄酸的结果为阴性。

Mitochondrial fatty acid oxidation is decreased, and peroxisomal and microsomal oxidation is complementally upregulated to decrease fatty acid accumulation.

线粒体脂肪酸氧化作用减少,过氧化物和微粒体氧化作用代偿性上调以减少脂肪酸的累积。

Cytochrome 〓 is a membrane-bound protein and can be proteolyzed to yield a soluble domain which contain...

细胞色素〓是一种电子传递蛋白,广泛存在于生物的微粒体、线粒体及血液的红细胞中。

This detoxification system is located in liver microsomes and requires uridine diphosphate glucuronic acid.

这解毒系统位于肝脏微粒体和需要二磷酸尿苷葡萄糖醛酸。

Heme oxygenaseis one of the important component of microsomal enzyme system,which can catalyze degradation of haemoglobin into bilirubin,ferri ion,and carbon monoxide.

血红素加氧酶是组成微粒体酶系统的重要组分之一,它能催化降解血红素生成胆红素、游离铁离子和一氧化碳。

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呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

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