微粒体

CHAPS efficiently solubilized the P450 of microsomes in midgut and fatbody, while lubrol PX , emulgen 911 and sodium cholate were less efficient.

对CHAPS、Lubrol PX、Emulgen 911和胆酸钠四种去垢剂的比较研究发现：CHAPS对中肠和脂肪体微粒体P450的增溶效率最高，Lubrol PX、Emulgen 911和胆酸钠较差。

Four detergents above mentioned didn't denature P450 of microsomes in midgut and fatbody at concentration of 0.5%.

在0.5％浓度下，四种去垢剂均未使中肠和脂肪体微粒体P450变性。

In the first part of this article, an HPLC method for the determination of nimodipine and its major metabolite was developed and applied to the study of the metabolism of nimodipine as well as enzyme kinetics in human liver microsome.

本文第一部分建立了人肝微粒体中尼莫地平及其代谢物的HPLC测定法，并用本法研究尼莫地平在人肝微粒体内的代谢及其代谢酶动力学，选择性CYP450酶抑制剂对尼莫地平代谢的影响。

Methods: Liver microsome was preparated from normal rat and human liver, which was to he treated with a series of concentrations of CsA or coadministration with Flu or MP. The activities of CYP3A in the microsomes were detected by using erythromycin as substrate.

制备大鼠和人肝微粒体，用不同浓度的CsA作用、加或不加MP、Flu，以红霉素为底物，经过NADPH系统孵育后，利用分光光度法测定人和大鼠肝微粒体的红霉素N-脱甲基酶活性。

During strawberry ( Fragaria ananassa Duch cv.chunxing) fruits maturation,the content of total sugar,anthocyanin and respiration rate increased significantly,and Ca 2+ _ATPase activity of cytoplasm and microsome membrane increased firstly,then peaked at pink stage,and decreased at full red stage in fruits,and also,the activity of plasma membrane Ca 2+ _ATPase was the highest in microsome membranes.

'春星'草莓果实成熟时，总糖和花青苷含量增加，呼吸速率也显著升高；同时，细胞溶质Ca2 + _ATPase活性和微粒体膜的Ca2 + _ATPase总活性变化具有相似的特点，即先升高，至粉红期达到高峰，全红期又下降，在微粒体膜中以质膜Ca2 + _ATPase占的比例最高。

Previous studies have found the major metabolic way of clivorine in male rat liver microsomes was to form pyrrolic metabolites. The above results suggested that there is sexual difference of metabolism in rats. The major in vitro metabolic way of clivorine in guinea pig was hydrolysis.

FMO的特异性抑制剂methimazo1e可以显著地抑制〓的形成，但对〓的形成无明显的抑制作用，且〓在肝微粒体中的形成为NADPH非依赖性，上述结果提示参与〓和〓代谢的酶分别为肝微粒体中的水解酶和黄素单氧化。

When the cytotoxic activity of these two types of TNF was compared, the synthesized 26kD TNF was found to exert its effects only in the presence of microsomal membranes.

比较这两种体外表达产物对靶细胞的细胞毒效应，结果表明，只有在微粒体存在时所合成的26kD TNF具有细胞毒活性；而无微粒体存在所合成的裸26kD TNF不显示杀瘤效应。

METHODS HPLC-UV assay was used to analyze chiglitazar concentration in microsomes incubation system.

方法采用高效液相-紫外检测的方法测定肝微粒体孵育液中西格列他钠的浓度，用特异性抑制剂的方法分析化合物的代谢酶，用大鼠肝微粒体体外研究西格列他钠可能的代谢产物和代谢途径。

And 0.5% or 0.8% CHAPS were suitable for solubilization P450 of microsomes in midgut and fatbody, respectively.

CHAPS增溶中肠和脂肪体微粒体P450的最适浓度分别为0.5％和0.5％或0.8％。

Results As shown in Western blot analysis, the presence of microsomes did not alter the molecular weight of TM-TNF , but it did result in the cleavage of the IL-2 signal peptide from S-TNFm,suggesting that the leader sequence of TNF might differ from the signal peptide of typical secretory protein in that it seemed not to have undergone cleavage during translation in the rough-faced endoplasmic reticulum.

结果 经Western blot 分析结果表明：微粒体的存在并不改变26×103 TM-TNF的分子量，但微粒体的存在能将S-TNFm上的IL-2信号肽切除，证实TNF引导序列与一般分泌性蛋白的&信号肽&不同，在粗面内质网翻译过程中不被切除。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。