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Methods: The health adult human primary hepatocyte microsome was randomly divided into 12 groups for control and itraconazole with different concentrations in the range of clinical drug blood concentration, each group have 10 samples. Control groups were added culture fluid, itraconazole groups were added itraconazole with different concentration respectively, after cultured 30 minutes, substrates (phenacetin for CYP1A2, testosterone for CYP3A4) were added and cultured for another 40 minutes.

采用健康成人肝细胞微粒体,分为对照组和不同浓度的伊曲康唑组,共12组,每组10个样本,伊曲康唑组分别加入血药浓度范围内不同对应浓度的伊曲康唑,对照组仅加入培养液,孵育30 min后,再加入CYP450同工酶1A2和3A4的相应底物再孵育40 min。

The substrates for measuring the activity of individual CYP in vitro included phenacetin, tolbutamide, debrisoquine, and omeprazole. RESULTS: Ther...

结果:CYP1A2、2C9及3A4的含量和活性具有很大的个体间变异,另外CYP2D6的活性在各样本间也有很大差异;CYP3A4(32%)是中国人肝微粒体中含量最丰富的CYP,CYP2C9(19%)和CYP1A2(16%)的含量也很可观;除了CYP1A2的含量和活性具有一定的种族和性别差异外,未发现其它CYP具有种族和性别差异;CYP1A2、2C9和3A4的酶蛋白含量分别和它们的活性具有很好的相关性。

Nanoparticles as a catalyst used in the semiconductor photocatalyst, especially in the area of organic preparation.

纳米微粒作为催化剂应用较多的是半导体光催化剂,特别是在有机物制备方面。

The results showed that the photoconductivity of AZO nanoparticles was improved greatly compared to that of bulk AZO due to nanometer size effect.

结果表明,由于纳米尺寸效应,AZO纳米微粒的光电导性能要比本体AZO颗粒好的多。

The result showsthat phthalocyanine LB film may be used as phase transition recording medium.

三、酞菁与半导体超微粒在溶液中的相互作用1。

The technological conditions, experimental equipment and physiochemical properties of nanocrystalline titania was studied.

对制备工艺、实验装置、TiO〓超微粒子的物理化学性质进行了研究。

In order to extract clear FECG,a new method called PICA was proposed based on Independent Component Analysis and Particle Swarm Optimizer.

为了清晰地提取出胎儿心电信号,提出一种基于独立分量分析与微粒群算法的胎儿心电提取方法??

Pinocytosis : Fluid or particles are engulfed by a cell.

胞饮作用胞饮指细胞呑入液体或微粒

About a beam of light with frequency ,the energy of the photon is where is Planck s constant.

1905年爱因斯坦对光的本性提出了新的理论,他认为,光束可以看成是由微粒子构成的粒子流,这些粒子叫做光量子,以后就称为光子,在真空中,每个光子都以光速运动,对于频率为的光束,光子的能量为

By study of the medium-acid plutonic rock and its maric microgranular enclaves of the middle Gangdis〓 belt, this dissertation will discuss the characteristics of the Gangdis〓 medium-acid plutonie magmatism and the crust/mantle dynamics during uplifting of Tibetan Plateau from the sight of material and energy, and use'lithoprobe'to connect crust and mantle interaction and other geologic events.

中、新生代青藏高原岩浆活动强烈,沿雅鲁藏布江缝合带形成了著名的冈底斯构造—岩浆带,本篇博士论文以冈底斯带中酸性侵入岩及其中铁镁质微粒包体为研究重点,探讨冈底斯带中酸性侵入岩浆活动特征,从物质和能量的角度论述了高原隆升过程中的壳/幔动力学过程,利用"岩石探针"将壳/幔之间的相互作用和地质事件有机地结合起来。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口,替代木托盘,免薰蒸,符合欧盟、北美各国对出口货物包装材料的法令要求;喷涂钢托盘适用于重载上货架之用,托盘表面根据需要制作成平板状、波纹状及间隔形式,满足不同的使用要求。

A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。