微核

The analyses of chromosomal aberrations and CBMN are an extremely reliable method in biological dosimetry.

提示染色体畸变和CB微核分析是非常可靠的生物计量估算方法。

The results showed YYSXF could raise survival rate of the mice after irradition, increase activity of superoxide dismutose and reduce quantity of the lipid peroxide in liver and red blood cell, extenuate micronucleus formating in V79 4 cell, promote unscheduled DNA synthesis and induce production of interleukin 2 in spleen cells and protect bone marrow cells in mice.

结果表明养阴生血饮能提高致死剂量照射动物30d和小剂量多次照射60d及荷瘤小鼠1次照射后20d的存活率；能增加超氧化物岐化酶的活性；降低过氧化脂质的水平；减少细胞的微核形成；促进脾细胞DNA修复；诱导脾细胞产生白细胞介素－2；保护骨髓造血功能

MATERIALS AND METHODS: The root tips of Vicia faba were treated with different concentrations of sodium sulfite and sodium nitrite (in the concentrations of 25;50;100;200;400 mg/L) with distilled water as control for four hours.The root tips of Vicia faba were stained with carbol fuchsin and examined. The micronucleus rate and the rate of chromosome aberration were determined within root tip cells of Vicia faba.

材料与方法：用不同浓度的亚硫酸钠和亚硝酸钠(25、50、100、 200、400 mg/L)分别处理蚕豆根尖4 h，并以蒸馏水作为对照，用石炭酸品红染液染色，分别观察、测定蚕豆根尖细胞的微核率和染色体畸变率。

In summary, our results suggest that ANE increases micronuclei frequency, induces cell cycle arrest at G2/M phase, causes cytokinesis failure and accumulates hyperploid cells. The events are possibly associated with ROS production, actin filament disorganization and centrosome aberration.

故从本实验的结果，我们认为槟榔子萃取物会增加微核频，诱导细胞周期停滞於G2/M phase，造成细胞质分缺损与多倍体细胞的增多；而这些现象可能与活性氧的生成，actin filament 的常与中心体的变有关。

Results Acute oral LD50 were 278 mg/kg and 56.2 mg/kg in rats and mice respectively, while dermal LD50＞2 000 mg/kg and inhalative LC50＞3 000 mg/m3. Skin and eye irritancy were estimated to be negative and mild respectively. Cumulative coefficient was 2.3 and allergic rate was 0%. A negative result was observed in Ames assay while increased frequencies of bone marrow micronuclei and spermatocyte chromosome aberrations were noted in the high dose (11.24 mg/kg) group.

结果 大小鼠急性LD50分别为278 mg/kg和56.2 mg/kg；大鼠经皮LD50＞2 000 mg/kg；急性吸入LC50＞3 000 mg/m3；无皮肤刺激性，轻度眼刺激性；蓄积系数2.3；致敏率为0；Ames试验结果阴性；微核和染色体在高剂量组(11.24 mg/kg)与阴性对照组相比有高度显著性差异(P＜0.01)；大鼠90天亚慢性经口的最大无作用剂量为2.825 mg/kg。

Effect of tenuazonic acid on micronucleus and karyokinesis of Vicia faba root tip cells was investigated to evaluate its cytogenetic toxicity.

利用蚕豆根尖为材料，研究了链格孢菌毒素细交链孢菌酮酸对细胞微核和有丝分裂的影响，以评价其细胞遗传毒性。

The recognition of Micronucleus Cell is rather difficult.

微核细胞的智能识别是一个较大难题。

It indicated that CB method increased precision and reliability for micronucleus assay.

表明CB 法提高了微核测试的灵敏度和可靠性。

Preliminary studies on the relationship between micronucleus formation and cell cycle I.

微核形成与细胞周期关系的初步研究Ⅰ。

The micronucleus rate was first increased and then decreased along with the increasing of the treated concn.

微核率随处理浓度的增加呈现先上升后下降的趋势。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。