微核

Results:the preservativecan increase significantly the frequency of micronuclei which were significantly different in comparison with control group;it can not increase significantly the frequencies of chromosomal aber...

结果山梨酸钾可明显引起微核率的上升，与对照组差异显著(P05)或极显著(P01)，不引起染色体畸变率的明显上升。3种物质均可降低山梨酸钾诱发的微核率和染色体畸变率。

The results indicated that when its concentration was 12.5~50μg/mL, no significant effect of tenuazonic acid on micronucleus ratio and karyokinesis index was found compared with control, the micronucleus ratio was less than 3‰ and karyokinesis index was more than 9.5%.

结果表明，当浓度为12.5~50μg/mL时，细交链孢菌酮酸对蚕豆根尖细胞微核率和有丝分裂指数不产生显著影响，微核率低于3‰，有丝分裂指数超过9.5%。

However, as the concentration increased to 100~400μg/mL, the micronucleus ratio significantly rose, while the karyokinesis index significantly decreased.

浓度升高到100~400μg/mL时，细交链孢菌酮酸使蚕豆根尖细胞微核率显著升高，有丝分裂指数显著下降，其中，400μg/mL时，微核率高达36.01‰，有丝分裂指数仅为1.90%。

The LD50 of Panax ginseng was above 100 g/kg. When Panax ginseng was in high dosage (20.0 g/kg) the number of macronucleus of mouse could be obviously increased, while normal dosage had no influence on it.

人参在高剂量(20.0 g/kg)时可以明显增加小鼠骨髓微核数，在正常剂量下对小鼠骨髓微核数无影响。

The micronucleus rate of sodium nitrite was higher than that of sodium sulfite at the some concentration.

在相同浓度下，亚硝酸钠诱导的微核率高于亚硫酸钠诱导的微核率。

Objective To investigate the statistical distribution of the data of cytokinesis-block micronucleus test to provide basis of statistical analysis.

目的 探讨微核试验数据（每1000个双核淋巴细胞中具有微核的淋巴细胞数）的统计分布，为微核试验数据的统计分析提供依据。

Methods Lymphocytes with different MTHFR C677T genotypes from the donors were cultured for 9 days in media with different concentrations of folic acid and the frequencies of micronucleated binucleated cell was evaluated by cytokinesisblock micronucleus cytome assay.

采用9天淋巴细胞长期培养辅以胞质阻断微核细胞组分析，分析不同浓度的叶酸对三种MTHFR C677T基因型乳腺癌人群和健康人群双核细胞微核率的影响与差异。

Results The micronuclear rate in medium dosage group and high dosage group were significantly higher than that of control group(P＜0.01). The ratio of sperm malformation in middle group and high group were higher than those of controls (P＜0.01).The ratio of sperm malformation increased in dose-dependent manner with dose, a dose-response relationship was found. Conclusion The DBP contamination presents the positive results under the certain dosage to the mouse marrow micronucleus experiment and the spermatozoon abnormal experiment.

结果 中、高剂量组微核率与阴性对照组相比明显升高(P＜0.05)，且各剂量组微核率随染毒浓度的增加而升高，呈现剂量-反应关系(r=0.937，P＜0.01)；中、高剂量组精子畸形率与阴性对照组比较差异有统计学意义(P＜0.05)，且各剂量组精子畸形率随染毒浓度的增加而升高，呈剂量-反应关系(r=0.904，P＜0.01)，畸形精子中以无钩为最多，其次是香蕉形、尾折叠、双头，分别为4.5%、3.09%和1.32%，结论 DBP染毒在一定剂量下对小鼠骨髓微核试验和精子畸形试验呈现阳性结果。

The microkemel and sperm cell abnomalities were analyzed. Results The micronuclear rate in medium dosage group and high dosage group were significantly higher than that of control group(P＜0.01). The ratio of sperm malformation in middle group and high group were higher than those of controls (P＜0.01).The ratio of sperm malformation increased in dose-dependent manner with dose, a dose-response relationship was found. Conclusion The DBP contamination presents the positive results under the certain dosage to the mouse marrow micronucleus experiment and the spermatozoon abnormal experiment.

结果 中、高剂量组微核率与阴性对照组相比明显升高(P＜0.05)，且各剂量组微核率随染毒浓度的增加而升高，呈现剂量-反应关系(r=0.937，P＜0.01)；中、高剂量组精子畸形率与阴性对照组比较差异有统计学意义(P＜0.05)，且各剂量组精子畸形率随染毒浓度的增加而升高，呈剂量-反应关系(r=0.904，P＜0.01)，畸形精子中以无钩为最多，其次是香蕉形、尾折叠、双头，分别为4.5%、3.09%和1.32%，结论 DBP染毒在一定剂量下对小鼠骨髓微核试验和精子畸形试验呈现阳性结果。

The Na_2SeO_4 and Na_2SeO_3 lead tothe existence of micronucleus and the abnormality of the nuclear. In the Na_2SeO_4 group,nuclear pycnosis and nuclear fission occurs, and in the Na_2SeO_3 group, nuclear pycnosis andnuclear concavity are the main symptoms.

导致红细胞产生微核及核异常， Na_2SeO_4暴露染毒组核异常主要表现为核固缩与核裂解，Na_2SeO_3暴露染毒组则主要表现为核固缩和核内凹。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。