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Restrictive changes of TCR Vp repertoire and clonal expanded T cells could be found in peripheral blood T cells from patients with T-ALL. However, the clonal expanded T cells' property (clonal expansion leukemic cells or leukemia antigen-specific expansion T cells) should be further characterized. It may play a certain role on detection of minimal residual disease and design of anti-leukemia idiotypic vaccine. The dominant utilization of TCR VjJ repertoire could be found in peripheral blood T cells from patients with B-ALL, meanwhile clonal expansive T cells were existed. It may be a feature of the host immune response for leukemia-associated antigen. The clonal expansive tendency of T cells in V021 and VP23 subfamilies was rather obvious, which may be correlated with certain malignant B-cell clone. The CDR3 sequences of monoclonal expansive T cell in T cell strains were different, which was the base of developing DNA vaccine.

T-ALL患者外周血T细胞的TCR Vβ谱系出现限制性改变,均可检测到克隆性增殖T细胞,尚需进一步鉴定其性质(肿瘤性或抗原特异性增殖),对于研究微小残留病变检测和设计抗白血病独特型疫苗均有一定的意义。B-ALL病人外周血T细胞的TCR Vβ谱系呈现优势利用的特点,并存在克隆性增殖的T细胞,这可能是机体对白血病相关抗原产生的特异性免疫反应;Vβ21和Vβ23亚家族T细胞发生克隆增殖改变的趋向性比较明显,可能与B-ALL相关抗原刺激有关。T细胞株中检测到的肿瘤克隆其CDR3序列具有高度的特异性,是构建DNA疫苗的基础。

Results MRI appearances of acoustic neuromas were:(1)The turmor's growth round the internal auditory canal,the Ⅶ,Ⅷ nerves affected side were thickened than that of opposite side.There was no marked demarcation between the main bodies of the tumors and the affected nerves.The connection between tumors and affected nerves could be showed at contrast enhanced imaging.(2)The tumors were of hypo or isohypo intensity on T1 weighted images and hyper or iso hyper intensity on T2 weighted images.(3)After Gd DTPA administration the tumors were homogeneously or inhomogeneously or circularly enhanced.(4)The margins of the tumors were smooth and well delineated.(5)The affected internal auditory canal usually became shorter in depth and larger in posterior anterior diameter.(6)MRI appearances of micro acoustic neuromas were that the affected Ⅶ,Ⅷ nerves were normal in size or nodularly thickened and the tumor reveaed nodular or point enhancement at contrast enhanced MRI.

结果 听神经瘤的MRI表现主要为:(1)肿瘤以内听道为中心生长,第Ⅶ、Ⅷ神经束较对侧增粗,与肿瘤主体多无明确分界,增强后可见两者相连,颇为特征;(2)肿瘤在T1加权图像上呈低信号、略低信号或低等混合信号,T2加权呈高信号或高等混合信号;(3)注射Gd DTPA后肿瘤呈均匀、不均匀或环状强化;(4)肿瘤边界清晰,边缘光整;(5)绝大多数肿瘤患侧内听道前后径扩大,深径缩短;(6)微小听神经瘤的MRI表现为第Ⅶ、Ⅷ神经束正常或局部结状增粗,造影后呈结节状或点状增强。

Happiness is not about being immortal nor having food or rights inone's hand.

幸福是每一个微小的生活愿望达成。

Happiness is not about being immortal nor having food or rights inone's hand.

幸福是每一个微小幸福的生活愿望达成。

Happiness is not about being immortal nor having food or rights inone's hand.

幸福是每一幸福个微小的生活愿望达成。

Happiness is not about being immortal nor having food or rights inone's hand.

幸福是每一个幸福生不老微小的生活愿望达成。

Happiness is not about being immortal nor having food or rights inone's hand.

幸福,不是长生不老,不是大鱼大肉,不是权倾朝野。幸福是每一个微小的生活愿望达成。

The enteric nervous system is composed of the ganalia and neurons within the wall of gastrointestinal tract and their interganglionic bundles.

肠神经系统由胃肠道壁内微小神经节及其神经元和节间束组成。

In some children, loose skin, discoloration, or tiny, dilated blood vessels may remain after the hemangioma has fully involuted.

一些孩子,当血管瘤完全消失后,可能会留下松懈的皮肤,变色,或微小的、扩大的血管。

Neo-impre ionism characterized by the use of tiny, closely aced dots or points of color that blend to produce a luminous quality.

新印象主义画法,用微小、密集的彩色点混合后产生一种夺目的效果。

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推荐网络例句

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。