强的松龙

OBJECTIVE: To assess the effect of 5 mg/day prednisolone on disease progression in patients with early rheumatoid arthritis receiving standardized disease-modifying antirheumatic drug therapy.

为评价早期类风湿患者在接受标准改善病情抗风湿药的治疗基础上中应用强的松龙5 mg/日治疗的有效性。

Results: 32 patients with PNS suffered from acute oliguria or anuria,acute deterioration of renal function and rising of serum BUN and SCr, excluding secondly glomerular disease and acute tubular necrosis?

结果 ：原发性肾病综合征在病情中突然发生少尿或无尿，肾功能急骤恶化，血尿素氮及肌酐上升，排除继发性肾小球疾病及其他原因引起的急性肾小管坏死、急性间质性肾炎和双肾静脉主干血栓形成，经甲基强的松龙和环磷酰胺或吗替麦考酚酯及标准疗程泼尼松、血液透析等对症治疗，32例患者肾功能均改善。

small dose is methylic the first selection that prednisone dragon can regard Mao Xi as cure of bronchitic little patient uses drug.

结论小剂量甲基强的松龙可作为毛细支气管炎患儿治疗的首选用药。

Small dose is methylic Mao Xi of prednisone dragon cure is bronchitic can alleviate quickly symptom of asthma hold back, shorten curative effect, cortisone of apparent excel hydrogen sulfide.

小剂量甲基强的松龙治疗毛细支气管炎能迅速缓解喘憋症状，缩短疗效，明显优于氢化可的松。

Objective To observe the effect of short-term systemic application of methylprednisolone on patients with acute exacerbation of COPD.

目的 观察短期全身应用甲基强的松龙在慢性阻塞性肺疾病急性加重期的疗效。

The patients were divided into two groups according to the diagnostic time:26 cases diagnosed in 48 hours were divided into the treatment group and 28 cases diagnosed after 48 hours were divided into the control group.Routine treatment was adopted in two groups,including management of the primary wound,mechanical ventilation in time,oxygen therapy,anti-infectious and hemostasia.

回顾性分析54例严重肺挫伤并发急性肺损伤患者临床资料，所选患者根据伤后48h内确诊本病与否分2组，早期防治组：26例，对照组：28例。2组除处置原发伤，及早机械通气，给氧，抗感染及止血常规处理外，确诊本病后及时采用综合防治方案甲基强的松龙250～500mg、白蛋白10g、速尿20mg，乌司他丁20万U+NS 20ml，1日2次静注。

There were fewer positive cells in other groups. The change tendency from few to many is control 2, MP3→MP2, MP4→control 1, MP1 Conclusions 1. Methylprednisolone is a very potential anti-scar drug and can elevate successful rate of rabbit filtration. 2. Used in the way of cotton patch, MP has lower ocular toxicity. Samely, high concentration could be got topically. 3. In definite range, the activity of MP is concentration-dependent. In other words, the activity can be promoted with the increase of concentration. Total results considered, 100mg/ml MP group is identified to have the best effect of all MP groups in the experiment.

； 实3组与对2组脯间差异不显著（Pl.05），但与其它继间差异显著①＜0.05）；实2组和实4组间差异不显著，但与其它各组间差异显著（P＜0.05人结论1、甲基强的松龙是—种很有潜力的低毒的摊痕抑制剂，可提高兔B湖过阶术的成功率；人甲基强的松溉用术中湿片贴敷的方式，既减轻了毒副作用，又可以达到局部用药的高浓度，是一种值得推荐的给药方法；3、在一定范围内，甲强龙的作用与浓度呈正相关关系，本次实验以 100ined组效果最好。

OBJECTIVE: To investigate reversible metabolic pharmacokinetics of prednisone and prednisolone in plasma and blood nucleated cells in 10 healthy male volunteers.

目的：研究强的松、强的松龙在10名男性健康志愿者血浆及血中有核细胞内的可逆代谢药代动力学。

The plasma and nucleated cells were separated from blood for HPLC analysis of prednisone, prednisolone and cortisol.

从血样中分离出血浆和有核细胞后用HPLC法测定强的松、强的松龙和可的松的浓度。

Eighty SD rats were randomly divided into four groups: acute spinal cord injury groups ( SCI groups, n=20);administration of Ulinastatin (U groups, n=20), use Ulinastatin after SCI at half an- and 4- and 8- and 24- and 48- hour.;administration of Methylprednisolone (M groups, n=20), use Ulinastatin after SCI at half an- and 4- and 8- and 24- and 48- hour; administration of Ulinastatin and Methylprednisolone(M+U groups, n=20), use Ulinastatin and Methylprednisolone after SCI at half an- and 4- and 8- and 24- and 48- hour;Allen's weight drop model of acute spinal cord injury was prepared.

本课题利用Allen重物打击模型，选用SD大鼠80只，随机分为四组：脊髓损伤组(SCI组，n=20)；使用乌司他丁组(乌组，n=20)；使用甲基强的松龙组(甲组，n=20)；乌司他丁+甲基强的松龙联合用药组(乌+甲组，n=20)，所有给药组在脊髓损伤后(半小时、4小时、8小时、24小时、48小时)给药。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。