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弛缓

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Objective: To report the clinical effect of treating esophaged achalasia with acupotomy.

目的:报告针刀治疗食管贲门失弛缓症的临床效果。

Objective:To investigate the clinical application value of laparoscopic modified Heller myotomy in treatment of achalasia.

目的:探讨腹腔镜改良Heller术治疗贲门失弛缓症的临床应用价值。

Aims: To investigate the quality of life in patients with achalasia, and the role of psycho-mental factors in the pathogenesis of achalasia.

目的:了解贲门失弛缓症患者的生活质量以及精神心理因素在其发病中的作用。

Background: Although symptoms of patients with achalasia are often related to psycho-mental factors, it remains unclear whether psycho-mental factors are involved in the pathogenesis of achalasia.

背景:贲门失弛缓症患者的症状常受情绪影响,但情绪因素在贲门失弛缓症发病中的作用尚不清楚。

The parameters of internal environment in rumen and the indices of autonomic nervous regulation were examined in 69 heads of cattle suffering from the alkaline forestomach atony and ruminal impaction.

对69例前胃弛缓和瘤胃积食等胃肠弛缓自然病牛的瘤胃内环境参数和植物神经调控指标进行了检测。

Being a new approach for treatment of gastrointestinal atony in ruminants, the carbonate buffer mixture can eliminate the gastrointestinal atony originated from the over acidity in gastrointestinal canal.

从而认为,对起因于胃肠酸碱环境改变的酸过多性胃肠弛缓疾病投服碳酸盐缓冲合剂可有效纠正胃肠弛缓状态,为反刍兽胃肠弛缓开辟了新的防治途径,创立了又一个病因一发病机理疗法。

METHODS Therapeutic effects of carbonate buffer mixture (Na2CO3 50 g, NaHCO3 420 g, KCI 20 g, NaCI 100 g, water 10 L) were observed in 120 cases of gastrointestinal atony including forestomach atony, rumen impaction, rumen acidosis, omasum impaction and intestinal constipation.

为进一步验证碳酸盐缓冲合剂对牛胃肠弛缓自然病例的治疗效果,对前胃弛缓(52例)、瘤胃积食(42例)、瘤胃酸中毒(18例)、瓣胃秘结(6例)、肠便秘(2例)等以酸过多性胃肠弛缓为临床特征的120例病牛投服了碳酸盐缓冲合剂(Na 2CO350 g,NaHCO3420 g,KCl 20 g,NaCl 100 g,常水10 L)。

Intravoneous injection of 0.5mg/kgBW jingsongling cause the 60 minutesrelaxation of goat gastric motor.The effects of jingsongling on the gastric motor ofgoat is major of effects of α2 -adrenoceptor agonist,as well as that of α1 -adrenoceptor agonist,the effects of α1 -adrenoceptor agonist concentrate at thecardic and pylorus;the function of α2 -adrenoceptor exit widely at cardic,pylorus,rumen,reticulum,omasum and abomasum,the function at different part is not the same.The lowestdose of jingsonglinginhibiting the amplitude and frequency of the gastricmyoelectric is 0.01mg/kgBW;the influence of jingsonglingto the gastricmotility of goat is dose-dependent,and the amplitude regain after the frequency ofgastric myoelectriv wave.When the goat revived,the gastric motor function is notreach the level of the normal;the major reason ofjingsongling cause the goat gastricrelaxation is the amplitude renew slowly.The intravoneous injection ofjingsonglingfirst,after 5 minutes,intravoneous injection the antagonist,the effect of prazosin and idazoxan mixed is best,which can fast reversal of theinhibition of jingsongling on the gastric motor of goat,the effects of idazoxan isgood,and the prazosin block the effection of jingsongling is better than that ofxylazine,especially at cardia and pylorus.When intravoneous injection of0.5mg/kgBW idazoxan and/or prazosin only,the amplitude of gastric myoelectric ingoat increases at a certain degree,but the frequency is not changed.

静脉注射0.5mk/kgBW的静松灵引起山羊胃蠕动弛缓长达60分钟;静脉注射0.5mg/kgBW的静松灵对山羊胃蠕动机能的影响是以α2肾上腺素受体作用为主的,兼有α1肾上腺素受体的作用,而且静松灵的α1肾上腺素受体的作用主要集中在幽门和贲门;α2肾上腺素受体的作用广泛存在于贲门、瘤胃、网胃、瓣胃、皱胃和幽门中,不同部位间有功能上的差异;静注0.01mg/kgBW的静松灵是对山羊的贲门、瘤胃、网胃、瓣胃、皱胃和幽门的肌电波频率和振幅均产生影响的最低剂量;静注一定剂量的静松灵对山羊胃蠕动的抑制作用与剂量呈相关性;而且山羊胃肌电波振幅的恢复比肌电波频率的恢复慢;苏醒时山羊的胃蠕动机能尚未恢复到正常状态;静松灵引起山羊胃弛缓的主要原因是由于胃肌电波的振幅恢复慢;静注0.5mg/kgBW的静松灵,5分钟后静注0.5mg/kgBW的拮抗剂时,咪唑克生+哌唑嗪的作用最好,能迅速地逆转静松灵对山羊胃蠕动的抑制作用,咪唑克生也有很强的拮抗作用,而哌唑嗪对静松灵的拮抗效果好于对隆朋的拮抗;单独静注0.5mg/kgBW的咪唑克生和/或哌唑嗪时,山羊的瘤胃、网胃、瓣胃、皱胃、贲门和幽门的肌电波振幅有一定程度的增强,而肌电波频率未见变化。

Abstract] Objective We assessed the usefulness of a laparoscopic Heller myotomy with a Toupet fundoplication for the treatment of achalasia.Methods LHT was performed in 30 patients who had esophageal achalasia with severe dysphagia.

摘要] 目的评价腹腔镜Heller术合并胃底折叠术治疗贲门失弛缓症的疗效方法 30例伴严重吞咽困难的贲门失弛缓症的患者实行了LHT。

The temporal evolution in transient reflectivity change ?嵇/R is composed of two relaxing parts: a fast component with time sub picoseconds and a slow component with time constant ranging from tens of ps to hundreds of ps.

瞬时反射率的变化主要由两个部份所构成:弛缓时间在次皮秒级(sub-picosecond)的快弛缓行为,以及弛缓时间在数十到百个皮秒的慢弛缓行为。

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