引起酸化的

Another interesting phenomenon is that when CaLP and p21 are co-transfected, the expression of p21 can stimulate CaLP translocate from cytoplasm to nucleus. By using methods of bioinformatics, point mutation and flow cytometry, we confirmed the importance of Y139 in the nuclear-cytoplasmic trafficking of CaLP.

激光共聚焦实验还发现当p21过表达时能够引起CaLP从细胞质向细胞核的转移，通过生物信息学方法，免疫共沉淀实验和流式细胞分析表明，CaLP的139位酪氨酸残基存在着较高的磷酸化潜力且在CaLP的核质穿梭和蛋白相互作用中起到了重要的作用。

Met hod: Hypertrophy of prostate model rat was established by injecting t estosterone to gelding male rats. After being treated with Qianlie Huichun ig 30 days, the rats were killed and prostate glands were resected for examination. The Fas expressio n was examined by immunobistochemical SABC.

采用大鼠去势后注射丙酸睾酮引起前列腺增生法造模，灌胃给药 30d后，处死大鼠取前列腺组织并称湿重，用免疫组化方法检测前列腺组织中Fas阳性细胞的表达率，用流式细胞术检测细胞凋亡率和观察细胞凋亡峰。

Cerebrotendinous xanthomatosis is a rare autosomal recessive disorder of bile acid synthesis, caused by impaired hydroxylation of cholesterol side chains due to deficiency of the mitochondrial enzyme sterol 27-hydroxylase （CYP27A1）, leading to accumulation of cholestanol and cholesterol in brain and other tissues.

文章摘要：脑腱黄瘤病是一种罕见的常染色体隐性遗传性胆汁酸合成障碍，由线粒体酶固醇27-羟化酶（CYP27A1）缺陷所致胆固醇侧链羟化受损引起，从而导致胆固烷醇和胆固醇在脑和其他组织贮积。

Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.

作为一个很有潜力的抗肿瘤物质，三羟异黄酮的作用机制主要包括：①抑制蛋白酪氨酸激酶活性，可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递，导致癌细胞增殖受抑；②弱雌激素作用：可通过与体内雌激素受体结合，并可增加细胞内性激素结合球蛋白的合成，增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性；③拓扑酶Ⅰ和Ⅱ抑制剂，抑制细胞活性；④上调细胞周期性负性调节因子P21WAF1/CIP1的表达，使之负性调节因子作用增强；⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长；⑥其他：抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。

The effects of the surfactants, trioctyl phosphine oxide, sodium dodecyl sulfonate and hexadecyl trimethyl ammonium bromide, on the extraction rate of Co^2^+ were investigated. The acceleration in the kinetics in contributed to the associated molecule~2 TOPO taking part in the extraction process directly. The decrement effects of SDS or CTMAB on the rate of extraction kinetics of Co^2^+ with HDEHP were also observed, which caused by the adsorption of molecules of SDS or CTMAB on the interface and decreased the interfacial adsorption amount of HDEHP. In addition, the extraction rate was reduced by a bigger margin in HDEHP-SDS system. This can be explained in terms of the formation of an electric field at the interface.

研究体系中加入不同表面活性剂所引起萃取速率的不同改变：三辛基氧化膦因与HDEHP形成可萃取的Co^2^+活性分子缔合物，降低了萃取过程活化能而使反应加速；十二烷基磺酸钠和十六烷基三甲基溴化铵因占据发生萃取反应的界面区，减小了HDEHP与Co^2^+反应的机会而使反应减速； SDS还因其在界面形成较强的负电场，造成Co^2^+的附加势能而使萃取速率有更大幅度的降低。

Injection of 0.06mg had no effect on the puparial color of SEM, and injection of 0.06 to 0.22mg ofβ-alanine gave an intermediate phenotype.

注射试验证明，SEM蛹的黑化可能是由于多巴胺的增多或β-丙氨酸的减少引起的。

Membrane CD14 not only recognizes LPS, but also induces tyrosine's phosphorylation, transposes NF-κB (nuclear factor-κB), triggers the release of cytokines, generates the oxygen free radicals.

细胞膜CD14识别LPS并引起细胞酪氨酸磷酸化、核因子(nuclear factor-κB， NF-κB)转位、触发细胞因子释放和氧自由基的产生。

Expression of human β-arrestin 1 attenuated κ andδ opioid receptor subtype-mediated G protein activation and inhibition of cAMP production, while did not affect the concentration- effect relationship ofμ-agonist 〓-enkephalin in the same signalings.

arrestin 1的表达明显减弱了κ型，δ型阿片受体亚型所介导的G蛋白的激活和腺苷酸环化酶活性的抑制，但是却不影响μ型阿片受体亚型特异性激动剂〓-enkephalin刺激引起的浓度效应曲线。

While the sample was dissolved in nitric acid and hydrofluoric acid, the silicon in sample was removed through evaporating in the form of silicon fluoride. As a result, the matrix interference was eliminated, and meanwhile the high blank value as well as the influence on the life span of graphite tubes due to perchloric acid was avoided.

使用硝酸和氢氟酸消解样品，使硅生成氟化硅蒸发掉，消除了基体的干扰，也避免了使用高氯酸作为消解试剂所引起空白值高及对石墨管寿命的影响。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。