引起酸化的

The results indicated that the leaching of acid rain led to increasing of latent acid of soil in short time though amortizing of soil to acid precipitation.

许多研究认为，人为酸化的因素主要有大气污染引起的酸雨输入 [2、3] 和施入氮肥引起的硝化作用 [4、5] 两方面。

Preparation of ratiometric pH nanosensors and its appication in intracellular pH detection of the anti-tumor drugs treated Hela cells The ratiometric pH nanosensors that contained a pH sensitive indicator fluorescein isothiocyanate and a reference dye tris(2, 2′-bipyidyl) dichlororuthenium hexahydrate had been prepared with O/W microemulsion method.

利用该内参比pH纳米传感器尺寸小可以通过细胞的内吞而无损伤地进入细胞内的优势，进一步结合流式细胞学分析方法，对不同抗肿瘤药物作用的Hela细胞内的pH变化进行了分析，结果表明：不同抗肿瘤药物作用后的Hela细胞内pH的变化情况并不一样，有的作用后引起了细胞酸化，有的作用后引起了细胞碱化，有的作用后基本上不引起变化。

Secondary pollution might be produced in the weak zone while conventional acidify because of halfway flowback under poor producing energy. Thief zones can obtain superfluous acidizing fluid because of the permeability contrast between layers of prominent interlamination antinomy, which can induce collapse in the thief zone and invalid acidification in the less permeable layers.

低压油气层常规酸化时由于地层能量低，导致残酸溶液无法彻底返排而引起地层的二次污染；层间矛盾突出的地层，由于渗透率差异，酸液将优先进入高渗地层，导致高渗透层进酸量多，从而过度酸化引起坍塌，低渗透层则由于进酸量少而达不到酸化的目的。

This article that focuses on the systematic and in-depth research in the current primal problem about abnormal burst pressure reservoir depress burst pressure has procured following main fruits:1 It forms the method which could obtain massive vertical static state mechanics parameters.2 In a foundation of acquisition of rock mechanics parameters,apply bent lamella that as mechanical model along with characteristic of actual geologic characteristics to analysis curvature for anticlinal strcture, get homologous tectonic stress value throug relation between the curvature and stress and different principal curvature in anticlinal structure,consequently set up laminational stress model for anticline reservoir. The block lamination for existed fracturing date has formed method of setting up mechanical model of lamination terrestrial stress by abtaining the block tectonic stress coefficients which are got by complex utilization test, laboratory test and fracturing date playback.3 Analysesing the main reason which lead to high burst pressure by considering the characteristic of reservoir geology,reservoir,and rock mechanics and reservoir damage,etc.Establishing burst pressure quantitative prediction model which provide gist for depressing construction risk and optimizing construction craft under the condition of open hole completion ,gun-perforated completion and damaged reservoir.4 Provding theoretical basis for interpreting acidification pretreatment which could depress busrt pressure by finding the relation between the influencing factors and rock machanics parameters and analysing the factors that have effect on rock mechanics parameters. Expounding the mechanism of reaction of mixed monomineral and acid from the angle of microcosmic element, evaluating quantitatively acid sensilility of different kinds of mineral effectively, and determing the first-order reaction dynamical equation of each mineral.5 Revealing rock mechanics property chage as a result of acid flooding in different condition by sandstone traumata experiment in different temperatures which combined with rock mechanics triaxial stress experiment.6 Associating damage mechanics with sandstone acidizing, established sandstone damage mechanics model in the foundation of the recognition on the rock mechanics parametric variation which is caused by acid-rock reaction in both macroscopic view and microscopic view ,also demonstrated those processes and quantitative estimated the acid busrt pressure to direct the site operation.

本文针对目前异常破裂压力储层降低破裂压力的主要问题展开较为系统和深入的研究，取得了以下主要成果：1形成了利用测井资料，结合室内岩芯测试结果，获取静动岩石力学参数的相关性特征，从而获得纵向上大量静态力学参数的方法。2在获取了岩石力学参数的此基础上，利用弯曲薄板作为力学模型，结合区块实际地质特征对背斜构造进行曲率分析，通过曲率与应力的关系，利用背斜构造不同部位的主曲率求得相应的构造应力值，从而建立起背斜储层的分层应力模型；对已有压裂资料的区块分层，形成了综合利用测试、室内实验、压裂资料反演获得该区块构造应力系数，建立起分层地应力的力学模型的方法。3综合考虑储层地质、油藏、岩石力学特性和储层伤害等因素，分析造成高破裂压力的主要原因，综合利用岩石力学、弹性力学等知识，建立了裸眼完井、射孔完井条件下以及储层受到伤害后的储层破裂压力定量预测模型，为降低施工风险和优化施工工艺提供了依据。4完成了物性、岩性影响岩石力学参数的因素分析，找出了各影响因素和岩石力学参数之间的关系，为从机理上解释酸化预处理降低破裂压力提供了理论基础；从微观元素的角度阐述了单矿物与酸反应的机理；并在此基础上，有效评价了各种矿物的酸敏感性，定量确定了岩石中各矿物的一级反应动力学方程。5完成了不同温度下的酸液类型、酸液浓度、注酸量等一系列砂岩损伤实验，结合岩石力学三轴应力实验，系统揭示了在不同条件下注酸而引起的岩石力学性质变化。6将损伤力学与砂岩酸化相结合，在宏观、微观两个方面认识酸岩反应引起岩石力学参数变化基础上，建立了砂岩损伤力学模型，并对其进行验证，在此基础上定量计算酸化后的破裂压力，有效指导现场施工

In humans, genetic defects of CathA cause galactosialidosis, a metabolic disease characterized by combined deficiency of CathA, GAL, and Neu1 and a lysosomal storage of sialylated glycoconjugates.

在人类，CathA的遗传缺失可引起半乳糖唾液酸沉积症，一种以CathA、 GAL、 Neu1不足和唾液酸化糖结合物在溶酶体的沉为特征的代谢疾病。

Erve growth factor can combine with its" receptor (one of tyrosine protein kinase receptor coded by proto - oncogene tyrosine kinase, TrkA), Causing the molecule of receptors to gather on the cell surface, and the tyrosine protein in cytoplasmic domain may be activated, three tyrosine base in the kinase domain of its" receptor and two tyrosine base at other domain be phosphated, thus, phosphated tyrosine receptor kinase became the bracket which absorb all kinds of connective proteins and kinases.

GF与其酪氨酸受体激酶受体(由原癌基因trk编码的一种酪氨酸蛋白激酶受体，TrkA)相结合，引起受体分子在细胞表面发生二聚体化，然后受体细胞内结构上酪氨酸活性被激活，使受体自身结构中位于激酶结构域的三个酪氨酸残基及在此结构域外的两个酪氨酸残基发生自身磷酸化，这样，磷酸化的酪氨酸受体激酶A便成为吸收各种连接蛋白质和酶的支架。

However, phosphotyrosine protein and Stat3 are subsequently activa ted through phosphorylation. In scar tissues, although EGFR has an intrinsic ty rosine kinase activity when activated by EGFR correlated ligand, phosphorylation of Stat3 showed no significant changes.

早期不同的配体刺激造成EGFR表达差异，随后导致酪氨酸蛋白磷酸化的不同，在正常的皮肤中Stat3磷酸化继续引起下游信号的表达，而瘢痕组织中Stat3磷酸化与正常情况无显著差别，造成信号不匹配。

The results showed that a neural structural relation between the NRF and the ventrolateral medullary surface does exist.

结果表明NRF与腹外侧表面存在神经结构联系，微量注射酸化人工CSF和DLH于NRF能引起呼吸活动加强，微电泳H〓主要引起NRF吸气相关单位兴奋，呼气相关单位抑制，提示NRF在中枢化学感受功能中也起着一定的作用。

The classification of acidification indices about the tested the litchi orchard soil: the first class was soil intensity index of exchangeable aciditypH(KCl, exchangeable acidity, exchangeable aluminium, titratable acidity, actual acidification velocity , cation exchange capacity or electrical conductivity; the second class was soil exchangeable Ca2+, total base or base saturation percentage; The third class was soil intensity index of active aciditypH

采用第一类酸化指标，pH2.5的酸雨淋溶引起了供试土壤的酸化；采用第二类酸化指标，除pH2.5的酸雨淋溶引起了供试土壤的酸化外，pH3.5的酸雨淋溶引起了供试土壤的表层土壤酸化；采用第三类酸化指标，pH≤4.5酸雨淋溶引起了供试土壤不同程度的酸化。

These organisms are responsible for the souring that occurs in the preparation of pickle s, sauerkraut, and Spanish-style olives

腌菜，酸泡菜，西班牙式青果的制备过程中发生的酸化就是由这些微生物引起的。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。