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The dose-response curve of histamine was shifted parallely to the right. pA2 was 9.34±0.61. The guinea-pigs were effectively reduced the rate of histamine induced death, decreased reaction extent of shock (P<0.01) and prolonged latency period of shock (P<0.05) by orally administered cetirizine ranged from 0.1, 0.2 and 0.4 mg.kg-1. The capillary permeability to intracutaneous injection of histamine was potently inhibited by orally administered cetirizine ranged from 0.0625 to 0.25 mg.kg-1 in mice, blue area obviously decreased (P<0.01), and dose-response curve existed obviously. In which the effect of these dosage groups were superior to the group of chlorphenamine.

结果:西替利嗪3×10-8~3×10-7mol.L-1可剂量依赖性地对抗组胺引起的肠肌收缩,使组胺的量效曲线平行右移,pA2为9.34 ± s 0.61,西替利嗪0.1,0.2及0.4 mg.kg-1口服给药时,能明显减轻豚鼠静脉注射组胺所致休克反应的严重程度(P<0.01),并可延长豚鼠惊厥反应的潜伏期及降低死亡率(P<0.05),西替利嗪0.0625~0.25 mg.kg-1口服给药可显著对抗组胺引起的小鼠皮肤血管通透性的增高,使蓝染面积显著缩小(P<0.01),且存在明显的量效关系,3个剂量组的作用均优于氯苯那敏组。

Either of them predisposes the spleen to torsion.1 Acquired wandering spleen can also arise in multiparous women during pregnancy when ligamentous laxity occurs owing to hormonal changes.2 Chronic torsion can cause splenomegaly.

腹痛由脾脏包膜的收缩或局部腹膜炎引起。此外,尚可见贫血、白细胞计数增多,乳酸脱氢酶升高等。影像检查主要包括超声、CT、核素成像、血管造影。

Overproduction of NO by iNOS is thought to be the principal factor of hypotension and hyporeactivity to vasoconstrictor agents observed in endotoxic shock.

特别是内毒素所引起之败血性休克时,iNOS产生过量的NO被认为是导致低血压,低收缩反应性血管及组织氧化性伤害的主要原因之一。

Studies have shown that nicotine in cigarettes can be the nerve center of exciting vasomotor and increased secretion of adrenaline, causing contraction of small arteries.

研究表明,烟中的尼古丁可以兴奋血管运动神经中枢,并使肾上腺素分泌增加,引起小动脉收缩。

In 66 anaesthetized rats, the effects of local injection of agmatine on femoral, renal, and mesenteric vascular beds were investigated respectively by constant flow perfusion method.

在66只麻醉大鼠,分别采用后肢、肾脏和肠系膜动脉在体恒流灌注法,观察了向灌流环路中直接注射胍丁胺(agmatine, AGM)的血管效应,以所引起的灌流压增减反映血管的收缩和舒张。

Methods The constriction induced by norepinephine (NE, 10-8-10-4 mol/ L) and diastole induced by acetylcholine (Ach, 10-8 -10-4 mol/ L) in thoracic aortic ring with angiosteosis induced by vitamin D3 plus nicotine in rats were recorded by BL-Newcentrary multichannel physiologic recorder.

维生素D3(VitD3)和尼古丁诱导大鼠血管钙化模型,通过BL-Newcentrary型多导生理记录仪,观察钙化大鼠离体胸主动脉环对去甲肾上腺素(norepinephine,NE)(10-8~10-4mol/L)和乙酰胆碱(acetylcholine,ACh)(10-8~10-4mol/L)引起的收缩和舒张反应。

After acetylating, the effect of the transformed PAF on platelet aggregation was compared with that induced by standard PAF for quantification.

目前发现PAF除引起血小板聚集外,还具有较为广泛的生物学作用,如增加血管通透性、促进白细胞趋化与激活、扩张血管、抑制心功能及收缩支气管等〔。

A stressful unhealthy lifestyle causes constriction of fine blood vessels in the skin.

一种紧张的不健康的生活方式引起在皮肤里好血管的收缩。

Methods The changes of contents of AGEs in plasma and the abdominal aorta and changes of VSMC of the abdominal aorta were investigated with methods of fluorospectrophotometry, immunohistochemistry, computer image analysis and transmission electron microscopy on streptozotocin-induced diabetic rats. Results From the fourth week, in diabetic rats, the contents of AGEs in plasma and the abdominal aorta increased, the relative area of α-SM-actin in the abdominal aorta decreased, the density of nucleus of VSMC increased, and mitochondria and rough endoplasmic reticules in VSMC increased.

后者在早期主要是血管平滑肌细胞(vascular smooth muscle cell, VSMC)和胶原纤维增多,弹性纤维减少,动脉增厚等,引起动脉的顺应性降低,舒张功能减弱[1~3];晚期主要表现为动脉粥样硬化和动脉硬化,其中以VSMC的增生和迁移较为突出,其表型也由收缩型转化为合成型[4,5]。

For example, cold weather makes the body's blood vessels, especially vulnerable to contraction and coronary artery spasm, easy insufficiency caused by the body and may lead to embolism.

比如气候寒冷使得人体的血管尤其是冠状动脉容易出现收缩和痉挛,易引起体内供血不足,并可能导致栓塞。

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We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称;三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起,称之为挽歌体诗人或者史诗诗人,他们被称为诗人,似乎只是因为遵守格律写作,而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。

This is not paper type of business,it's people business,with such huge money involved.

这不是纸上谈兵式的交易,这是人与人的业务,而且涉及金额巨大。