引起失调的

As for how allyl chloride caused calcium imbalance is stable future needs furt her study a major issue.

至于氯丙烯如何引起 Ca2+稳态平衡失调是今后需要进一步研究的一大课题。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

The highest point reached in the apparent motion of a celestial body.

缺乏运动协调；有明显的运动失调特点或由运动性共济失调引起。

2Nd, internal cause: In life because of emotion change; Post-natal has not obtained the full recuperation; Pressure build-ups and so on work, family create the mood despondently and so on.

内外因素的共同作用导致内分泌失调、皮肤代谢失调，引起性激素分泌改变，皮脂腺堵塞、产生炎症，黑色素代谢异常，最终导致了痤疮、色斑等肌肤病症的产生。

In lens-induced experimental myopias of guinea pigs, increasing of MMP-2 and decreasing of TIMP-2 occur in posterior scleral matrix. This pair of disbalance of MMP-2 and TIMP-2 can cause abnormal growth of guinea pig's eyeball.

透镜诱导豚鼠实验性近视眼巩膜基质中MMP-2活性增强，TIMP-2活性降低，二者平衡失调可导致巩膜胶原的降解，巩膜壁变薄，引起眼球扩张，眼轴延长。

This current is known as the input offset current, and it is caused by bias currents of active devices as well as by leakage currents through insulators within the INSTRUMENT .

这个电流就是输入失调电流，它可能是由有源设备的偏置电流引起的，也可能是由仪器内的绝缘体泄漏电流引起的。

Shows that pressure is an important incentive cancer, Chinese medicine practitioners believe that the pressure led to fatigue resulting体虚decline in immune function, endocrine disorders, stress can also lead to mental stress caused by Qi stagnation blood stasis, and drugs such as fire invagination.

可见压力是重要的癌症诱因，中医认为压力导致过劳体虚从而引起免疫功能下降、内分泌失调，压力也可导致精神紧张引起气滞血淤、毒火内陷等。

Environmental problems can be essentially considered as the unbalance between human beings and nature in the social development.

环境问题是人类在社会发展过程中引起的人与自然和谐关系的失调，就其本质而言是由人的不当活动所引起的。

In H2S concentration of 50 – 500 ppm, headache, vertigo, weakness, naupathia, balance maladjustment, short of breath, accumulation of liquid in lung and the loss of consciousness etc.

长期低浓度接触，引起神经衰弱综合症和植物神经功能紊乱。50- 500ppm 能引起头疼、眩晕、虚弱、恶心、平衡失调、呼吸的困难、肺中积液、意识丧失等症状。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失