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Due to the insufficiency of KEYNES and invest-output methods, the authors analyze the increasing of national economy resulting from highway investment multiplicator, propose a theory of calculating highway investment multiplicator based on the original definition of investment multiplicator, and obtain an improved method to calculate th.

为了完善利用公路建设投资乘数计算公路投资对国民经济拉动效益的方法，针对目前利用凯恩斯乘数与投入产出法计算公路建设投资效益的不足，通过公路建设过程中投资乘数作用引起国民经济成倍增长的机理分析，提出从投资乘数的原始定义出发计算公路建设投资乘数的原理，推导了计算公路投资乘数时公路建设投资引起的边际消费的改进算法，并通过京石高速公路有关资料验证了该方法的效果；发展了基于投资乘数计算原理、现有公路工程投资测算、投入产出矩阵组合基础之上的应用方法，克服了常用算法用全社会的消费倾向代替公路投资消费倾向的不足。

Results:①In normal extracellular solution, the non-selective cholinergic agonist acetylcholine and the muscarinic agonist muscarine both caused the increace of [Ca2+]i in separately 21 out of 25 and 14 out of 18 VHCs I, while only 3 out of 20 and 2 out of 16 VHCs I had a weak increase of [Ca2+]i if investigated in calcium free extracellular solution; nicotine could increase the [Ca2+]i in 7 out of 32 VHCsⅠonly at enough high concentration(up to 10 mmol/L) in normal extracellular solution, this [Ca~(2+)]_i increase by nicotine at high concentration could not be investigated if at calcium free solution.

结果①非选择性胆碱能受体激动剂乙酰胆碱、M型胆碱能受体激动剂毒蕈碱在正常细胞外液中均可引起大部分(21/25， 14/18)单离VHCⅠ[Ca~(2+)]_i的升高，但无钙外液中ACh、muscarine仅使少部分(3/20，2/16)VHCⅠ[Ca~(2+)]_i升高且作用减弱；正常外液中，N型受体激动剂尼古丁仅在高浓度(≥10 mmol/L)时引起部分(7/32) VHCⅠ[Ca~(2+)]_i升高，在低浓度时对胞内钙离子浓度影响不明显，无钙外液中，10 mmol/L nicotine对胞内钙离子浓度影响不明显。

Analysis of nuclear extracts of human cells has indicated a similar excision repair mechanism for nick-directed mismatch correction in higher cells, and several reconstituted systems that rely on purified human proteins have been described, such as hMutSα、hMutSβ、hMutLα. Recently, scientists discovered that nickel could be inhibitors of DNA repair. Nickel can greatly enhance the mutagenicity and genotoxicity of compounds in cigarette by inhibiting the nucleotide excision repair pathway in human cells. We have confirmed that nickel could inhibit MMR of E. coli and human and presumed that nickel inhibited repair before MutH incision of the MMR in E. coli. However, there is no evidence of mechanism of nickel inhibiting MMR in human cells.

镍是存在於香菸中的微量金属，近年来有学者发现镍是DNA修复反应的抑制剂，长期抽烟的人会容易因为香菸中化合物攻击DNA而引起突变，进而引起肺癌，而镍会抑制核苷酸移除修复系统（nucleotide excision repair；NER），所以使得体内的DNA损伤无法修复；过去实验室已经证实大肠杆菌的核酸配对错误修复系统会受到镍等重金属的抑制，并且推测出镍的抑制反应是抑制在修复反应的上游nicking的步骤；另外，也证实了人类的核酸配对错误修复系统也会受到镍的抑制，然而还没研究证实会抑制在核酸配对错误修复反应的哪个步骤。

The inhibition of Myostatin expression can accelerate the myoblast proliferation and myofibril hypertrophy, which results in the skeletal muscle hyperplasia.

对该基因表达的抑制可引起成肌细胞的过度增殖和肌纤维的肥大，从而引起骨骼肌增生。

Such as inflammation of joints, the lower leg, such as chronic venous insufficiency lead to long-term sustainability of the skin caused by congestive hairy; hyperthyroidism in Pretibial myxedema patch Department often long acuminatum out; hypothyroidism and limbs of children in the back outside a large number of hair growth; children with viral encephalitis and inter-brain barrier after mumps-induced systemic hairy; head injury, especially after the children more prone to hair; children with primary malnutrition or enteropathy, or other malabsorption, or severe infections caused by malnutrition could rise to a large number of multi-body hair; anorexia nervosa patients in the face, trunk and upper limbs have more hair grow; infant limb pain patients in the limbs, face, trunk and more hair; dermatomyositis patients, mainly in children can be located hairy forearm, leg and temporal, but also a broader scope; Berordinelli syndrome, that is, growth and maturity accelerated from an early age, and accompanied by malnutrition and intestinal muscle atrophy, common hepatomegaly and high blood fat, the skin of patients with rough, often hairy; addition of certain drugs such as streptomycin, such as cortisone can cause iatrogenic hairy; some women as a result of adrenal, ovarian and other diseases caused by increased androgen can also result in more hair.

如炎症性关节，小腿慢性静脉机能不全等导致长期持续的皮肤充血造成多毛；甲状腺机能亢进者在胫前粘液性水肿的斑块处常有粗毛长出；甲状腺机能减退的儿童背部和四肢外侧有大量毛发生长；儿童在病毒性脑炎及流行性腮腺炎后间脑障碍所致的全身性多毛；头部外伤后特别是儿童易发生多毛；儿童原发性营养不良或肠病，或其他吸收不良，或严重感染引起的营养不良均可引起大量全身性多毛；神经性厌食症患者可在面部、躯干和上肢有较多的毛发长出；婴儿肢痛病患者可在四肢、面部、躯干部多毛；皮肌炎患者，主要发生于儿童中，多毛可位于前臂、小腿和颞部，但范围也更广泛；Berordinelli综合征，即生长和成熟从小就加速，并伴有肠营养不良和肌肉萎缩，常见肝肿大和高血脂，其患者皮肤粗糙，常多毛；此外某些药物如链霉素、可的松等可造成医源性多毛；某些妇女因肾上腺、卵巢等疾病致雄性激素增多也可造成多毛。

Nano- and non-nano-Al2 O3 could induce the activities of Kupffer cells in rat livers. However, apoptosis induced by NAOs increased significantly than that induced by nNAOs, which may be related to the metabolism characteristics of the two Al2 O3 particles in rat livers.

NAOs及nNAOs均能引起大鼠肝组织中枯否细胞活化，但NAOs引起肝组织细胞凋亡的程度高于nNAOs，可能与两种不同粒径的氧化铝在肝组织的代谢特征不同有关。

The cause of bone marrow mecrosis is manifold and mainly related with neoplastic diseases.

引起骨髓坏死的原因是多种多样的，但最主要的原因是由恶性赘生性疾病引起。

It may be because the external ear dysplasia caused by hearing impairment, such as cochlear dysplasia, are curable by surgery; if it is caused by nerve connection, you need not worry too much pessimism and 宝宝 are still very small, in the infancy of the metabolic capacity of a strong , has many defects can be improved through its own, this is Doctor allows you to review the causes of each month.

它可能会因为外耳发育不良引起的听力障碍，比如耳蜗发育不良，是可以通过手术治愈的；如果是神经方面引起的，您也不用太悲观，宝宝还小，在婴儿时期的代谢能力很强，有很多缺陷都是可以通过自身完善的，这也是医生让您每月复查的原因。

The human's conflict which derive from the nescience and warp is much more derisible than the conflict which derive from the benefit.

人类因无知和偏见引起的冲突，有时比利益引起的冲突更可笑。

These initial symptoms can oerlap considerably with those of other cardiac and non-cardiac conditions, including neuroleptic malignant syndrome, which may itself be caused by antipsychotics.

这些始发症状可与其他的心脏和非心脏原因引起的疾病症状相叠加，包括可由抗精神病药物引起的抗精神病药恶性综合征。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。