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Using the methods of classical shape size measuring and chromosome analysis, we studied the morphological characters and Karyotype of Cobitis sinensis in Xiangjiang River. We also investigated the evolution line and Karyotype polymorphism of the C . sinensis by the methods of cytological classification and cytocatalytic. Our results suggest that the formation of chromosome polymorphism was concerned with heterologous hybridization and some of C . sinensis may perpetuate in a clonal manner by natural gynogenesis.

本文以湘江流域的中华花鳅为研究对象,运用经典的形态测量观察方法、染色体制片技术对中华花鳅的形态生态特征、染色体组型进行了初步研究:运用细胞分类和进化方法对中华花鳅的核型演化和核型多态现象的形成进行了分析,提出:其核型多态的形成牵涉到鳅科鱼类的异源杂交,某些中华花鳅可能是行雌核发育生殖的。

It was also found that the chromosomes paired well and formed a rod heteromorphic bivalent in the hybrid F1[73(36)9-1×CSDT 1BL]. Whereas 73(36)9-1 produced mainly configuration of 20''+1'+t' when test-crossed with CSDT 1BS. It showed that the translocation occurred on chromosome 1B short arm, and this segment came from rye chromosome 1RL. In the present paper we discussed also the way in which the translocation might be caused, and concluded that it was formed through reunion of two kind telocentrica (1BL and 1RL) after simultaneous misdivision of two univalent chromosomes (a wheat chromosome 1B, and a rye 1R).

同时还发现,73(36)9-1和"中国春"双端体的1BL能很好地配对并形成一个棒状的异形二价体,而它和CSDT 1BS的染色体则主要产生20+1′+t′的构型,从而证明易位发生的可能途径,推断是由于在F1花粉母细胞中的两个单价体(一个是小麦染色体1B,一个是黑麦染色体1R)同时进行错分裂之后产生的两种端着丝点染色体(1BL和1RL)重新并合形成的,因而冬小麦73(36)9-1可能是一个自发产生的易位系。

In addition, we presume that the role of different MMPs is distinct in various stages of EMs development. The difference of subjects which is resulted by the genetic difference of MMP-1 has the association with the risk of EMs, and the abnormal expression of protein may have relation with the development of EMs; The abnormal expression of MMP-3 has a very important role in the development of EMs; As a protein of endothelial expression, MMP-7 may participate in the development of EMs, endometrial cells with high-expression MMP-7 easily take place ectopic implantation in the blood of menstruate countercurrented and increase the risk of EMs; It is not confirmed in our study that there are the association of MMP-9 with the risk of EMs, but in view of other study, we will further evaluate the role of MMP-9 in the development of EMs.

且推测不同的MMPs基因在子宫内膜异位症发生和发展的不同阶段作用不同,MMP-1基因的遗传差异所导致的个体差异与子宫内膜异位症发病风险的个体差异相关,其蛋白的异常表达还可能与子宫内膜异位症的进展相关;MMP-3基因的异常表达在子宫内膜异位症的发展中起重要作用;MMP-7作为一个上皮性表达的蛋白,可能对子宫内膜异位症的发生起重要作用,带有MMP-7高表达的在位子宫内膜细胞更易在经血逆流中"异位"种植,增加个体子宫内膜异位症的发病风险;MMP-9虽然在本研究中没有被证实与子宫内膜异位症的发生和发展有相关性,但鉴于其它相关研究,有待于从其它方法证实MMP-9在子宫内膜异位症进展中的作用。

According to the above study result, the diversity of microorganisms population in the SUFR system is complex and the bio-community formed in the SUFR system is stable. The close relations between abundance of bacteria and nutrients were found. The correlation between heterotrophic bacteria and COD was 0.949. The correlation between organic phosphate bacteria and TP was 0.815. The correlation between nitrosobacteria and NH3-N was 0.909. The correlation between disnitrifier bacteria and TN was 0.653. These inneglectable great factors effecting on phosphorus-uptake and phosphorus-release of phosphorus accumulating organisms are the influent COD、the concentration of DO、the sludge retention time、the temperature. The diversity of organic phosphate bacteria population in the SUFR reactor was complex and there is no phosphate bacteria taking the absolute superiority in quantity. The near-native pure culture method powerfully complement the traditional pure culture technique and enrich culture technique. The sludgy bioactivity is very good in whole SUFR reactor. By the quality of being biochemistry, the anaerobic phase is higher than anoxic phase and the anoxic phase is higher than aerobic phase of SUFR.

通过以上试验内容研究发现,SUFR 系统中的微型动物种群较多,微生物生态系统稳定;系统中微生物的数量与营养盐的含量密切相关,其中总异养菌与COD的相关系数r 为0.949,有机磷细菌与TP 的相关系数r 为0.815,亚硝化菌与NH4+-N的相关系数r 为0.909,反硝化菌的数量和TN 的相关系数r 为0.653;污水生物除磷工艺中进水COD 的浓度、DO 浓度、泥龄的长短、温度都是影响聚磷菌释磷及吸磷效果的不可忽视的因素;SUFR 系统中的磷细菌呈现种群多样化的趋势,没有占绝对优势数量的磷细菌;微孔滤膜近自然培养法是对传统纯培养技术和富集培养技术的有力补充;整个SUFR 反应器系统中污泥的生物活性很好,就可生化性来讲,厌氧反应器大于缺氧反应器大于好氧反应器;按照动力学方程式求出的细胞生长动力学特征值和SUFR 脱氮除磷系统工艺的实测值结果基本吻合。

Bitter compounds in saliva activate particular T2R/TRB isoforms activate gustducin heterotimers, activated α-gustducin stimulates PDE to hydrolyze cAMP, the decreased cAMP may disinhibit cyclic nucleotide-inhibited channels to elevate intracellular Ca2+.

唾液中的苦味化合物激活T2R/TRB同型体,这种激活导致味导素异聚体的激活,被激活的α-味导素又激活PDE,PDE水解cAMP,cAMP水平的降低使环核苷酸抑制的阳离子通道去抑制,从而使细胞内Ca2+升高。

Salty and sour directly transduction by apical channels that are non-gated channel or chemically-gated channel. Bitter compounds in saliva activate particular T2R/TRB isoforms which activate gustducin heterotimers, activated α-gustducin stimulates PDE to hydrolyze cAMP, the decreased cAMP may disinhibit cyclic nucleotide-inhibited channels to elevate intracellular Ca2+.

咸和酸直接通过顶部非门控或化学门控离子通道转导唾液中的苦味化合物激活T2R/TRB同型体,激活导致味导素异聚体的激活,被激活的α-味导素又激活PDE,PDE水解cAMP,cAMP水平的降低使环核苷酸抑制的阳离子通道去抑制,从而使细胞内Ca2+升高。

Bitter compounds in saliva activate particular T2R/TRB isoforms which activate gustducin heterotimers, activated α-gustducin stimulates PDE to hydrolyze cAMP, the decreased cAMP may disinhibit cyclic nucleotide-inhibited channels to elevate intracellular Ca2+.

唾液中的苦味化合物激活T2R/TRB同型体,这种激活导致味导素异聚体的激活,被激活的α-味导素又激活PDE,PDE水解cAMP,cAMP水平的降低使环核苷酸抑制的阳离子通道去抑制,从而使细胞内Ca2+升高。

Systemic levels of IL-6, IL-8 and TNF- a increase in patients with acute pancreatitis and correlate with the severity of the disease.A key regulator of cytokine induction is the pleiotropic transcription factor nuclear factor- K B.

核因子-κB(nuclear factor-kappa B,NF-κB)是由Rel蛋白家族成员形成的同源或异源二聚体,它几乎存在所有的细胞,不同的二聚体与不同的DNA序列结合,亲和力和转录激活能力是不一样的。

The synthses of a new type of surfactant-sodium bis sulfuo-succinate was first reported, it could form reversed micelle with iso-octane. This reversed micellar system could extract macromolecular protein-hemoglobin as well as cyt-C.

首次报道了一种新型表面活性剂丁二酸二酯磺酸钠的合成,考察了它与异辛烷形成的反胶束体系在提取小分子的细胞色素C和相对分子质量较大的血红蛋白的行为。

For metabolites of strain SIPI-800, three active compounds were found, named as SIPI-800-1, 2 and 3 respectively, moreover SIPI-800-1 was new compound showing immunosuppressant activity and moderate anti- anaerobic activity; 2 and 3 were isoflavones with estrogenic activity, attracting activity to fungal zoospores, inhibiting alcohol dehydrogenase and aldehyde dehydrogenase I activities.

对SIPI-800菌株的代谢产物研究,分离出3个活性化合物,分别命名为:SIPI-800-1、2和3,其中1化合物为文献没有报道的新化合物,具有免疫抑制活性(1ug/ml浓度抑制NK细胞88.9%的活性)和弱的抗厌氧菌活性;2和3为异黄酮化合物,分别为Daidzein和Genisten的7甲基化衍生物,具有雌激素活性、强吸引真菌游动孢子、抑制乙醇或醛脱氢酶等活性。

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The split between the two groups can hardly be papered over.

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