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The isothermal amplification step depends not only on the replication of DNA polymerase, but also on the scission of nicking enzyme, which can generate a great number of aptamer.

我们用该方法对细胞色素P450酶系中的异喹胍羟化酶的单碱基多态性(CYP2D6*10)进行了检测,使突变型和野生型基因DNA得到了很好的区分。2。

Objective To investigate the value of sequential and quantitative analysis of donor chimerism to predict the outcome of allogeneic hematopoietic stem cell transplantation, to determine the optimal time point of adoptive immunotherapy and to estimate the efficacy of adoptive immunotherapy.

目的探究供体细胞嵌合率的动态定量检测在预测异基因造血干细胞移植后的转归,确定过继免疫治疗时机和评价AIT疗效中的作用。

Moreover, RIM-BP3 and Hook1 mutant mice share several common abnormalities, in particular with regard to the ectopic positioning of the manchette within the spermatid, a presumable cause for the sperm head deformities.

而且,RIM-BP3和Hook1的突变小鼠具有一些共同的表型,尤其是精子细胞中精子领的异位分布,这是造成精子头部异常的潜在原因之一。

Cholesterol contributes to the generation and development of atherosclerosis while non sterol isoprenoids play a role in regulation of cell proliferation, signal transduction and ge...

胆固醇在动脉粥样硬化的发生、发展中起重要作用,而异戊二烯则参与细胞增殖调节、信号转导及肿瘤发生过程。目前,该酶已成为一些有效的抗动脉粥样硬化药物治疗的靶点。

However, alkylating agents, such as cyclophosphamide, and the topoisomerase II inhibitors, doxorubicin and epirubicin, are associated with two types of cytogenetically distinct leukemias after adjuvant chemotherapy.

然而,烷化剂如环磷酰胺、拓扑异构酶II抑制剂、阿霉素、表阿霉素都与辅助化疗后的两种细胞遗传学不同的白血病的发生相关。

Autophagy is one of the major degradative pathways in eukaryotic cells,and it is the only one with the capacity to degrade entire organelles.

我们发现,细胞自我吞噬通路基因的突变体的体细胞在胚胎发育早期以及幼虫早期,会有P颗粒的异位聚集。

Objective To investigate the condition about cell differentiation and distribution in the super-thin epidermal graft, confirming the existence of phenomenon of cell ectopy during wound repair.

目的:了解超薄表皮片移植中干细胞的分化和分布的状况,初步探讨创面修复过程中细胞异位现象的存在。

In this review, we discussed the consequences of inhibiting histone deacetylases in cycling versus non-cycling cells, in light of the dynamics of histone acetylation patterns with a specific emphasis on heterochromatic regions of the genome.

本综述通过讨论HDACIs对周期和非周期细胞中组蛋白去乙酰化酶的抑制结果,来阐明组蛋白乙酰化模式的动力学特征,特别是对基因组异染色质的作用。

Objective To investigate whether novel isoflavone and steroid derivatives have better antitumor activity.

目的 研究改构后的异黄酮及甾体类化合物是否具较好的体外抗细胞增殖的活性。

Robertson and his colleagues discovered that isothiocyanates may block the activity of Akt3 protein, which is overactive in approximately 70% of melanoma tumors and thought to promote tumor growth by preventing cell death.

Robertson和他的同事发现了异硫氰酸盐类可能阻断Akt3蛋白的激活,Akt3蛋白可以激活接近70%的黑色素瘤而且通过阻断细胞死亡来促进肿瘤的生长。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力