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VCM increased the HRPE cells' proportion of phase S (6%~13%)and heteroploid was found in VCM with 250 and 500 mL/L vitreous.

VCM促使更多的HRPE细胞进入了DNA合成期(S期,6%~13%),含250与500mL/L玻璃体体积的VCM使HRPE细胞出现了异倍体的改变。

During the esophageal canceration course, DNA content and heteroploid rate increased significantly. Cell cycle distribution changed obviously. Expressions of relevant cell cycle regulatory elements were abnormal.

食管上皮癌变过程中,DNA含量及异倍体率增加,细胞周期分布发生了明显的改变,细胞周期相关基因蛋白表达异常。

The expression rates of CD44V5+ CD44V6+, cerbB-2+ cells in patients with metastasis, multi-metastasis nodes, DNA heteroploid, SPF elevated, and Apo decreased were higher than those of patients with non-metastasis, only one-metastasis node, DNA diploid, SPF non-elevation and Apo non-decreasing, respectively (P.01 or 0.05), while nm23+, DCC23+ and p16+ were contrary.

肿瘤转移者、多器官转移者、DNA异倍体者、SPF增高者、APO不减低者的CD44V5+、CD44V6+、cerbB-2+细胞表达率均显著高于未转移者、单器官转移者、DNA二倍体者、SPF不增高者、APO不减低者(P.01或0.05)。而nm23+、DCC+、p16+细胞的表达率与此相反。

The gene regulating sequence of human collagen type Ⅰ is located at 5'end and first intron. The carriers of reporting gene was made, and the function of promoter, enhancer and inhibiter was examined in this study. On the basis of above work, MBP ectopic expression carriers were further built. The result laid a foundation for investigating the feasibility, and validity to specially express MBP gene of human nervous system, in tendon fibroblast.

人Ⅰ型胶原基因调节序列位于5'端和第一内含子,本研究构建了带报告基因的载体并检测了其启动子,增强子和减弱子的功能,以此为基础,进一步构建了MBP异位表达载体,为探索在神经系统少突胶质细胞特异表达的人脑髓鞘碱性蛋白MBP基因转至肌腱成纤维细胞表达的可行性和有效性奠定了基础。

Objective To investigate the clinical significance of monocyte chemotactic protein-1 (MCP-1) produced by endometriotic tissues.

目的 探讨异位子宫内膜细胞产生单核细胞趋化蛋白-1(MCP-1)的临床意义。

Weeks after operation, around 2 kinds of materials had obvious connective tissue. The histology slice observation, we discovered has connective tissue proliferation, and few inflammatory cell infiltration. And some osteoblast around the material arrangement regulation, around the material had a kind of ossein and the chondroid structure appearance.

术后4W,2种植入材料周围有明显的结缔组织包裹,组织学切片观察,发现有结缔组织增生,其间有炎性细胞浸润,有成骨细胞在材料周围规则排列,有异位成骨趋势,材料周围已有类骨质和软骨样结构出现。

To examine the influence of systemic factors on aged progenitor cells from these tissues, we established parabiotic pairings (that is, a shared circulatory system) between young and old mice, exposing old mice to factors present in young serum. Notably, heterochronic parabiosis restored the activation of Notch signalling as well as the proliferation and regenerative capacity of aged satellite cells.

为了查明系统因子对来自这些组织的衰老祖细胞的影响,我们在幼鼠和老鼠之间建立了共生态配对试验(即:一种共享的循环系统),给老鼠输入含有年轻因子的血浆,奇怪的是,异时性共生态细胞Notch信号重新激活,同时恢复了衰老干细胞增生和再生能力。

The effect of bavachin and corylin, two active principles from Psoralea corylifolia L., on UMR106 cyclin E expression by Western blotting was examined. The result showed that the two flavonoid compounds had no significant effect on cyclin E expression after various exposure time.

对于中药补骨脂中分离的两个促成骨样细胞增殖的活性成分补骨脂二氢黄酮和补骨脂异黄酮,采用Western blotting的方法考察不同时间对UMR106细胞周期蛋白cyclin E的表达,结果它们对cyclinE的表达没有显著影响。

The whole cell-patch clamp recording technique was used to record I in specific pipette solution and superfusion according to specific holding potential and command potential program.

采用经典的酶分离心肌细胞方法,应用全细胞膜片钳技术记录I,观察MI后I、的变化,予以β2受体激动剂salbutamol、β受体激动剂异丙肾上腺素及不同选择性β受体阻滞剂后I的变化。

Topoisomerases uncoil DNA before cell division, and altering the work of the enzyme leads to tumor cell death.

拓普异构酶在细胞分裂前使DNA解旋并改变酶功能导致肿瘤细胞死亡。

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