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It was noted that cell death from necrosis and autolysis would produce false-positive result because of non-specific DNA fragmentation.

提示类似泡状核细胞这类异染色质较少的细胞凋亡时可能都具有这种表现。

The peroxisome proliferator-activated receptors play an important role in adipocyte differentiation and fatty acid metabolism, activation of PPAR may induce the differentiation of adipocyte,influence the expression of genes involved in lipogenesis and fatty acid oxidation,eventually lessen ectopic fat accumulation and improve the impaired insulin signaling,so the medicine which targets to the control point of FFA metabolism would be hopeful in the treatment of a cluster of metabolic abnormalities resulted from insulin resistance.

过氧化物酶体增殖物激活受体在脂肪细胞分化、脂肪酸代谢中起重要作用,PPAR及其所调控基因的激活可促进脂肪细胞分化、减少脂质产生、增加脂肪酸氧化,从而减少脂质的异位沉积,进一步改善损伤的胰岛素信号转导通路,逆转胰岛素抵抗。针对脂肪酸合成及氧化的关键调控点的药物可能是今后治疗胰岛素抵抗引发的一系列代谢异常的新的靶点。关键词过氧化物酶体增殖物激活受体;脂肪酸代谢;胰岛素抵抗

That PI and the percentage of the cells in s-phase of the borderline/malignant and heteroploid/aneuploid tumors were higher ted to higher mortality and relapse rate as well as the corresponding risk. Because of the changable characters and dissociative phenomenon of the tumor, the measurement of PI and the percentage of cells in s-phase may be disturbed in few of diploid tumor and in part of double DNA stem ones. Therefore other paramet- ers should be added to analyse before making any conclu- sion.

交界性和恶性、异倍体或非整倍体肿瘤的PI和S期细胞百分率较高,病死加复发率和相对危险性增加;由于肿瘤的异质性和"分离现象",对于少数2倍体肿瘤和部分双DNA干系肿瘤PI和S期细胞百分率的测定易受干扰,故应结合其它参数综合分析。

Moreover,the othervariants,for example,single egg situated in far from micropyle part,double antipodaland antipodal replacement egg apparatus.

此外还观察到其他一些变异结构,如单卵异位、单卵双套反足细胞和反足细胞团取代卵器形成"假卵器"等。

Results: electronic microscope showed that in prednisone group heterochromatin increased in some cells, entoblast was not obvious in some cells, fat drops were small and few, mitochondria vacuole were common, and myelin figure was found in smooth endoplamic reticulum. the ultrastructure in yc group was almost normal and megamitochondrion formation was common. a large amount of fat drops were found in cytoplasm in gw group and little improvement was found compared with that in prednisone group.

结果: 电镜结果显示:激素组个别细胞异染色质增多,核仁不明显,脂滴显著变小变少,线粒体空泡化常见,有滑面内质网髓鞘样结构形成;养阴组电镜结构基本正常,其特征是细胞内有较多的巨大线粒体形成;桂附组较激素组改善不明显,其特征是胞质内可见大量脂滴。

Mdr-l gene and its D-gp expression might be in association wi th the MDR of glioma cells.Verapamil, erythromycin and dihydropyridine could rev erse MDR of glioma cells.

mdrl基因及其P-gp蛋白的表达与胶质瘤细胞产生的MDR有关;异搏定、红霉素和潘生丁对胶质瘤细胞MDR有逆转作用。

Result:The content of cholesteatoma tissues and postauricular skin specimens are a normal euploid.

结果:胆脂瘤上皮细胞和外耳道上皮细胞的核型均为二倍体,未见异倍体。

The changes included that the protrusions on the cell surface diminished, myofilaments and pinosomes in the myoepithelial cells of grade Ⅱ,Ⅲ atypical hyperplasia decreased, and the irregularity of the nuclear morphosis and the increase of nuclear heterochromosome were found.

乳腺不典型增生时肌上皮细胞数目增多,排列紊乱,电镜下可见:①细胞表面的棒状突起消失;②Ⅱ、Ⅲ级不典型增生时胞浆内的肌微丝和吞饮小泡减少;③细胞核增大,不规则,异染色质增多。

Vacuoles and black dense particles usually occurred in cytoplasm of heterokaryon, and occasionally, swelling of mitochondria, pycnotic nuclei or even enucleation process could be seen among hybrid cells.

超微结构分析表明,杂交细胞表面膜微绒毛、指状突及皱褶突等均明显减少,核内异染色质比例增高,核仁数目减少或消失,细胞质中常可见有空泡或黑色致密颗粒出现;少数杂交细胞出现线粒体肿胀、核固缩甚至排核现象。

The NPC patients with DNA heteroploid are more easily to emerge distant metastases than those with DNA diploid.

采用流式细胞术检测新鲜组织细胞的DNA倍体性和临床分期一样可以预测鼻咽癌患者的预后;DNA异倍体患者比二倍体患者更容易出现远处转移而导致治疗失败。

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