异种移植

Statistical analysis was calculated by a one-way ANOA with Dunnett as a post-test and the two-tailed unpaired t test using GraphPad prism software.

在体内实验中，抗人类胰腺(AsPC-1)异种移植鼠肿瘤模型表明两种药物联用有更好的耐受剂量及时间方案。

However, there is some defects in the properties of DAF, such as its limited decay-accelerating activity and lacking of cofactor activity of I factor, which limited its usage in clinic.

然而， DAF仍存在某些缺陷，比如其有限的衰变加速能力并缺乏Ⅰ因子的辅因子活性限制了DAF的临床应用，其为部分病原微生物受体的角色对异种移植有潜在危险。因而对DAF进行改造是一种较好的选择，也是当务之急。

A useful, easy and stable model has been established for the investigation of the mechanism of the concordant xenotransplantation.

建立了一种简便、实用、稳定的用于协调性异种移植免疫排斥反应发生机制的动物模型。

Objective:To research expression and function of c-myc gene in hyperacute r ejection of xenotransplantation.

目的：研究c-myc基因在异种移植超急性排斥反应时的表达及功能。

Five models were used to investigate the "Changdong"" s anti-tumor effect: mice S180 sarcoma solid model, mice liver cancer H22 solid model, mice Lewis lung cancer model, as well as human liver cancer QGY and colon cancer LOVO implanted in naked mice; mice liver cancer H22 was also used to evaluate the enhancive effect of "Changdong" when it was co-applied with other anti-tumor agent or with radiotherapy; The "Changdong"" s cytotoxic effect in vitro on such tumors as QGY, LOVO, lung cancer A549, breast cancer MCF-7, as well as mice leukemia P388 was observed through MTT method. And investigate the effect of "Changdong" on proliferation of spleen lymphocyte, on activity of NK cell and on synthesis of IL-2 in mice bearing Lewis lung cancer, respectively. With propidium iodide straining, cell aigptosis and cell circle were analyzed by flow cytometry. Result:"Changdong" has an evident tumor inhibitive effect on mice tumor model as well as human tumor implanted in naked mice with a quantity-effect relationship.

使用小鼠S180肉瘤、小鼠肝癌H22实体瘤和小鼠Lewis肺癌模型，以及人体肝癌QGY和人体肠癌LOVO裸鼠异种移植模型，进行"长动"的抗肿瘤药效学研究：用小鼠肝癌H22进行"长动"合并放疗和化疗的增效作用研究；用MTT法进行"长动"对肝癌QGY、肠癌LOVO、肺癌A549、乳腺癌MCF-7、小鼠白血病P388等10株人体和动物肿瘤细胞的体外细胞毒性作用研究；用淋巴细胞转化试验、小鼠NK细胞活性试验、小鼠胸腺细胞增殖法分别测定"长动"对荷Lewis肺癌小鼠的脾淋巴细胞增殖的影响、自然杀伤细胞活性的影响和对小鼠产生白介素-2(IL-2)的影响；用流式细胞仪PI单染色法进行"长动"对人体肝癌QGY细胞的体外诱导凋亡作用和对肿瘤细胞周期的影响的研究。

The hEGcs can be used in heterotransplantation ,and the transplanted cells migrate from the epicardium to the myocardium and differentiate into cardiac myocytes gradually.

人EG细胞可异种移植，人EG细胞在大鼠心肌梗死处由心外膜层逐渐向心肌层迁移。

It is an important event of diologic safety which attention must be paid to potential hazard of infectious interspecies transmission of PERV during xenotransplantation.

因而，在猪异种移植过程中PERV传播的潜在危险仍然是必须高度重视的生物安全性问题。

Therefore,it is importance task that we should not only knockout α-1,3GT and relative molecules from pigs,but also ensure safety in public health of XP from PERV.

因此，即要剔除导致人类排异反应的猪细胞表面的α-1，3GT及其相关的分子，又要确保猪器官异种移植的安全性，是尚待研究的重大课题。

The contribution of platelets to hyperacute rejection of both allografts and xenografts is well recognized.

血小板在同种异体移植和异种移植超急性排斥反应中的作用是受到广泛认同的。

Methods: The hEGcs from the gonadal ridges and dorsal mesenteries of human embryos aged 5-10 weeks were cultured with or without cytokine in culture medium to observe their growth and the effects of different cell culture systems were compared.

目的：优化人胚胎生殖细胞的体外培养体系，并将生长状态良好的传代的人EG细胞移植用于大鼠心肌梗死模型的治疗，探讨人胚胎生殖细胞进行异种移植对大鼠心肌梗死的治疗机制。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。