异种免疫的

A useful, easy and stable model has been established for the investigation of the mechanism of the concordant xenotransplantation.

建立了一种简便、实用、稳定的用于协调性异种移植免疫排斥反应发生机制的动物模型。

BACKGROUND: Deproteinized cancellous bone can be used as a new kind of bone graft material due to its wide resources and biological characteristics if the problem of immunogen can be solved.

背景：异种脱蛋白松质骨因其来源广泛和独特的生物学特性有望成为较好的骨组织工程支架，其关键点为免疫原问题，如能解决免疫原问题，则有望开发出一种新型植骨材料。

Objective:To explore the effects of IL-10 on acute leukemic immune evasion.

目的 探讨IL-4和IL-10在诱导异种骨移植免疫耐受中的作用。

Exogenic transplanted MSCs were not immune rejected,and did not initiate specific immune response during the second transplant.

MSCs异种移植未见明显的免疫排斥，不诱导机体产牛特异件免疫应答，多次移植可以改善功能恢复。

Although the deelopment of relatiely non-toxic immunosuppressie or tolerance-inducing regimens will be required to justify clinical trials using pig organs, recent adances in our understanding of the biology of xenograft rejection and zoonotic infections, and the generation of alpha1,3-galactosyltransferase-deficient pigs hae moed this approach closer to clinical application.

尽管用猪的器官去验证临床试验需要相对无毒的免疫抑制剂或致耐的方法，但随着近来我们对异种移植排斥生物学及动物传染病感染的深入理解，以及α1，3 半乳糖转移酶缺陷猪的产生，异种移植更接近临床应用。

Objectives To study the role of spleen in liver xenogenic rejection of Hamster to Rat.

目的 探讨脾脏在仓鼠到大鼠异种肝移植中的体液免疫、细胞免疫作用。

Cellular immune response would occur later and would be weaker in xenogenic hepatocellular transplantation.

在异种肝细胞脾内移植中，细胞免疫发生的较迟和/或较弱。

We observed the changes of the proprioceptors in the partly injuried ACL and the xenogeneic graft/artificial graft being used to reconstructing the injuried ACL with gold chlorid staining method and laser copolymerization electron micrography method to observe the morphological changes of the neuromechanism in the ligament tissue,with RT-PCR method to evaluate the proportion and the regeneration of the nerve component and with HRP retrograde tracking technology and electrophysiologic study to judge the functional changes of the neuromechanism in the ligament tissue,respectively.

本研究分别制作兔ACL部分损伤动物模型、异种肌腱移植物重建损伤ACL动物模型和LARS人工韧带重建损伤ACL动物模型，分别于术后不同时间点对损伤ACL/移植物进行氯化金染色光学显微镜检查和PGP9.5免疫荧光染色后激光共聚焦电子显微镜检查观察韧带内神经结构形态学变化，用RT-PCR法检测韧带中GAP-43和PGP 9.5的mRNA表达情况以评价损伤ACL/移植物内神经成分比例及神经再生情况，通过HRP逆行追踪技术和电生理检查(包括体感诱发电位和腘绳肌肌电图)评价损伤ACL/移植物内神经结构的功能情况。

Optionally, hematopoietic stem cells, autologous, syngeneic, allogeneic or xenogeneic, are delivered to increase the speed of regeneration of the patient's immune system.

可选择地，输入自体的、同种同基因的、同种异基因的、或异种异基因的造血干细胞，来增加患者免疫系统重建的速度。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。