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The contribution of platelets to hyperacute rejection of both allografts and xenografts is well recognized.

血小板在同种异体移植和异种移植超急性排斥反应中的作用是受到广泛认同的。

Objective: To evaluate the role of xenoreactive nature IgM in hyperacute rejection in cardiac xenotransplantation model from guinea pig to rat.

目的:了解大鼠体内天然抗体IgM在非协调性异种心脏移植超急性排斥反应中的作用。

Methods The in vitro cultured porcine vascular endothelial cells and human sera were co-reacted to set up an in vitro model of hyperacute rejection of pig-to-human xenotransplantation.

用体外培养的猪血管内皮细胞和不同人的血清共同反应,建立猪与人异种移植超急性排斥反应的体外实验模型。

On base of analysis to simulation result, it was point out the main cause making dissimilar metal"s bonding so difficult was metal"s inharmonic plastic deformation. The distribution and changement of stress and strain on interface and in workpieces were analyzed.Making use of experiment and simulation result, main factors that influence welding property of cold pressure welding were discussed.

通过对模拟结果的分析,说明了异种金属冷压焊较同种金属冷压焊困难的原因主要是界面处两种材料的径向和轴向的不协调塑性变形;直观地显示了冷压焊过程中工件内部及界面处的应力应变分布及变化情况。

The law how these factors influence the joint"s property was pointed out. A formula about the relationship between extrusion times and contamination remainder was founded. Main reason to bimetal"s inharmonic deformation was the difference of their mechanical property. Thereby, the empirical formula showing the relation between metal combination"s mechanical property and quality of joint was constructed. Integrated influence of extrusion times and metal"s mechanical property to quality of cold pressure welding joint was discussed.

在模拟结果分析和实验的基础上,对影响异种金属冷压焊焊接性的工艺因素进行了分析;探讨了诸因素对接头性能的影响规律,并且建立了挤压次数与界面污染物残留量之间的数学表达式;指出了两种材料力学性能差异是造成不协调塑性变形的主要原因,并且建立了材料力学性能与其冷压焊焊接性之间的经验公式;定性的讨论了挤压次数及材料力学性能对冷压焊接头性能的综合影响。

In contrast, there are truncated proviral sequences that have the capacity to retrotranspose, causing insertional mutagenesis in the xenograft and in infected human cells.

相比较而言,被截短的前病毒序列有逆转录转座作用,能够导致异种移植物以及被感染的人类细胞的插入突变。

OBJECTIVE: To explore the performance of xenogenic deproteinized bone scaffold for tissue-engineered bone and the effect on spinal intertransverse fusion in goats.

目的:探讨异种脱蛋白松质骨作为骨组织工程支架的性能,及其在山羊脊柱横突间融合中的作用。

[Objective]To study the properties of xenogeneic deproteinized bone used as scaffold in the bone tissue engineering and its application to the spinal fusion of the lumbar intertransverse process in a goat.

作者:高春阳,孙革,韩冬梅,李罡,周斌[目的]探讨异种脱蛋白松质骨(deproteinization bone,DPB)作为骨组织工程支架性能及其成骨作用。

Posterolateral Lumbar Intertransverse Process Spinal Arthrodesis With Composites Composed Of Recombinant Human Bone Morphogenetic Protein 2 And Allograft Or Xenograft; Or With Composite Consisted Of HA And Xenograft in rabbitsBackground: So far spine arthrodesis remains to be used in spine surgery.

中文题名rhBMP-2、HA及其复合物在兔腰椎后外侧融合的实验研究副题名外文题名论文作者杨发军导师马忠泰教授学科专业外科学研究领域\研究方向临床技能训练与研究学位级别博士学位授予单位北京大学学位授予日期2001 论文页码总数92页关键词骨形态发生蛋白异体骨移植脊柱融合异种骨移植馆藏号BSLW /2001 /R687 /42 背景:目前,脊柱融合手术被广泛地应用于脊柱外科领域,自体髂骨仍是被最常用的骨移植物,但是其有5%-35%的不融合率。

RESULTS ① rhBMP2/BCB used alone was capable of healing the defect in large part by 16 wk, with a similar repair process and mechanism to that seen with RBX;② use of rhBMP2/BCB in conjunction with vascularized periosteal graft exhibited stronger defect-repairing power, basically healing the defect by 8 wk. The repair process consisted of intramembranous and endochondral ossification that resembled the physiological repair during the fracture healing.

结果①单纯rhBMP2/BCB移植,可在16 wk使节段性骨缺损基本修复,其机制与过程与重组合异种骨相似;②rhBMP2/BCB与带血循骨膜联合移植,仅用8 wk即可修复骨缺损,其修复机制与骨折修复相仿,包括膜内成骨和软骨成骨两种机制。

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