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This intermediate is responsible for the stereoselective nucleophilic substitution and the subsequent racemization of 3-EtO-NDZ enantiomers in acidic ethanol.

该中间体导致了3-EtO-NDZ对映异构体在酸性乙醇中所发生的立体选择性亲核取代反应及随后的消旋过程。

The in vitro anticancer activities of the ruthenium complexes were screened by MTT assay.

采用MTT法评价了3种异构体对多种肿瘤细胞株的体外抗肿瘤活性以及对正常细胞的毒性。

Mordenite has a significant effect on the activity of catalyst, results of test showed: with soluble glass as main feedstock and addition of crystal precursor, thecrystalization time can be reduced, and the synthesized mordenite has higher surface area and structure of small crystal particulate and big pore diameter. Through ion exchange with ammonium and acid, the synthesized mordenite is suitable to prepare isomerization catalyst.

丝光沸石对催化剂活性有较大影响,试验结果表明:以水玻璃为主要原料,加入晶种可缩短晶化时间,合成的丝光沸石具有较高的比表面积及小晶粒大孔径结构,经铵交换及酸交换后适于制备异构化催化剂。

The compounds are represented by the structural Formula 1, Chemical formula should be inderted here as it appears on the abstract in paper form. a prodrug thereof, or any pharmaceutically acceptable salt, solvate, isomer or racemic mixture of the compound or said prodrug wherein R1 is heteroaryl, N-arylaminocarbonyl, N-heteroarylaminocarbonyl, benzimidazolyl or benzothiazolyl; R15 is present or not and if present is H, aryl, alkyl, arylalky or heteroarylalkyl; A is aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene or heterocycloalkyl wherein said aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene and heterocycloalkyl moieties may be substituted or unsubstituted; and B, L, X and R18 are defined herein.

所述化合物用结构式1表示,包括其前药或所述化合物或所述前药的任何药学上可接受的盐、溶剂合物、异构体或外消旋混合物,其中R 1 为杂芳基、N-芳基氨基羰基、N-杂芳基氨基羰基、苯并咪唑基或苯并噻唑基;R 15 存在或不存在,如果存在,则为H、芳基、烷基、芳基烷基或杂芳基烷基;A为芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基或杂环烷基,其中所述芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基和杂环烷基部分可被取代或未被取代;B、L、X和R 18 如说明书所定义。

The importance of stereochemistry and hence the need for enantioselective analytical methods has long been recognized especially in pharmacokinetic studies.

而这两个化学结构相似的镜像异构物却常有著不同的药效与药动性质。

John Cornforth (b. 1917) and Vladimir Prelog (1906-98) shared a 1975 Nobel Prize for work on stereochemistry and stereoisomerism of alkaloid s, enzymes, antibiotics, and other natural compounds.

康福思和普雷洛格在立体化学以及生物碱、、抗生素和其它天然化合物的立体异构方面做了许多工作,因而共获1975年的诺贝尔奖。

John Cornforth (b. 1917) and Vladimir Prelog (1906-98) shared a 1975 Nobel Prize for work on stereochemistry and stereoisomerism of alkaloids, enzymes, antibiotic s, and other natural compounds.

康福思和普雷洛格在立体化学以及生物碱、、抗生素和其它天然化合物的立体异构方面做了许多工作,因而共获1975年的诺贝尔奖。

CoA by strengthening TCA pathway, and the methylmalonyl??CoA is formed from succinyl??CoA by isomerization. Finally, methylmalonyl??CoA can be used as the precursor for the biosynthesis of erythromycin.

餐?戊二酸,再生成琥珀酰CoA,琥珀酰CoA在甲基丙二酰CoA异构酶的作用下生成甲基丙二酰CoA作为红霉素合成的前体。

Identification and Molecular Analysis of Superoxide Dismutase Isoforms in Helicobacter Pylori.

幽门杆菌的超氧化物岐化脢异构物的识别和分子分析。

The difference in solvent polarity environment between excited state intramolecular charge transfer and proton transfer states leads to a remarkable ESICT/ ESIPT coupled reaction. In polar, aprotic solvents, in contrast to a unique PT tautomer emission observed in 3-hydroxyflavone (3HF), dual emissions are resolved, consisting of ESICT and ESIPT bands.

不同於化合物3-hydroxyflavone只观察到异构物的质子转移萤光放射峰的结果,在极性、非质子酸溶剂里,我们会观察到3-hydroxyflavone衍合物有两个萤光放射峰,是分别经由ESICT与ESIPT两种不同路径个别的贡献。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。