异构的

By the analysis of the process of manufacture information and the trend of CAPP development, the dissertation points out that CAPP system has to be developed as contemporary CAPP system with the characteristics of intelligent process planning and management, supporting PLM-oriented Web-based collaborative work.

本文基于产品全生命周期管理思想，探索分布异构的动态企业应用环境下的计算机辅助工艺设计Web协同工作的模式和方法，支持产品信息的全生命周期演化，支持新产品的快速创新过程，对于缩短敏捷制造企业的产品开发周期、降低产品成本、提高产品质量具有十分重要的理论和现实意义。

With the continuous development of computer science and technology, the application systems in the future will be multilayer ones based on the object oriented, distributed, isomerous conditions. This kind of system is composed of distributed objects one by one, which have given functions singly. These objects are independent of network protocols, programming languages, and software and hardware platforms. These pro- perties make them communicate each other and work corporately.

随着计算机科学技术的不断发展，未来的应用系统将主要是建立在面向对象的、分布的、异构的、自治的环境中的多层应用系统，系统主要由一个个分布式对象组成，对象各自具有特定的功能，可以跨越平台，独立于网络协议、编程语言和软硬件平台，实现相互通信，协同工作。

How to mine useful knowledge from massive, distributed, isomerism, half structurized, dynamic Web data becomes the new task of the data mining and the engineering research.

如何从这些巨量的、分布的、异构的、半结构化的、动态的Web数据中发现有用的知识是数据挖掘和知识工程研究面临的新课题。

In this thesis,the AM1,MNDO,MINDO/3(mainly AM1)and INDO/S-CI semiempirical MO methods were used toinvestigate the excited-state intramolecular protontransfer reactions of salicylic acid derivatives—salicylic acid,methyl salicylate,salicylaldehyde,o-hydroxyaceto-phenone,salicylamide and 3-hydroxy-picolinamide (6 conformers and 2-3 anion species);2-(2'-hydroxy-5' methylphenyl) benzotriazole(4 conformers),2-(2' hydroxyphenyl) benzimidazole (3 conformers and 3anion species),Bis-2,5-(2-benzoxazolyl)hydroquinone(3 conformers),2-(2'-hydroxyphenyl)benzothiazole(2conformers) and 7-azaindole dimer (2 conformers).Theinvestigations were described as follows.Geometry optimization,relative stability andhydrogen bonding energy First,for sylicylic acid derivative molecules,the AM1,MNDO and MINDO/3 methods were used toinvestigate ground-state geometry optimization,energies,relative stabilities and hydrogen-bondingenergies on the five kinds of the molecules(designing 6 conformers and 2-3 anion species).Comparing with experimental data,the optimizedgeometry,the order of stability,the hydrogen-bonding energies and the distances between O-O in O-H..O hydrogen bonds by AM1 method were in agreementwith the experimental data,however,the C-C bondlengths optimized by MNDO and MINDO/3 were longer,C-O and O-H bond lengths were shorter;for C-N bondlengths,the results opitimized by MNDO method werethe same as those by AM1 method,nevertheless the C-Nbond lengths given by MINDO/3 method were muchshorter.For some sylicylic acid derivatives(e.g.methyl salicylate,salicylamide),the order ofstabilities on the conformers given by MNDO andMINDO/3 methods were not in agreement with theexisting conformers deduced by experimental methods,and the hydrogen bonding energies calculated by MNDO.and MINDO/3 methods were smaller.Second,the studyon the other systems found that the optimizedgeometry of the proton-transfered product with INDOmethod could not be obtained,only could theoptimized geometry of reactant be obtained,and thecalculated hydrogen bonding energies were greater.Many results of calculation indicated that the studyon the excited-state intramolecular proton transferreaction system using AM1 method was suitable andreliable.

本论文用AM1、MNDO、MINDO/3（主要是AM1）和INDO/S-CI半经验分子轨道方法对水杨酸衍生物系列——水杨酸、水杨酸甲酯、水杨醛、O-羟基乙酰苯酮、水杨酰胺和3-羟基吡啶酰胺（6种异构体和2-3种阴离子）；2-（2'-羟基-5'-甲基苯基）苯并三〓唑（4种异构体）；2-（2'-羟基苯基）苯并咪唑（3种异构体和3种阴离子）；2，5-二间氮杂氧茚氢醌（3种异构体）；2-（2'-羟基苯基）间〓杂硫茚（2种异构体）和7-〓吲哚二体（2种异构体）的激发态分子内质子转移反应在以下几个方面进行了较系统的理论研究：几何构型优化和相对稳定性及氢键能首先以水杨酸衍生物系列分子为例，用AM1、MNDO和MINDO/3方法考察了5种分子（每种分子设计6种异构体和2-3种阴离子）的基态几何构型优化，能量、相对稳定性和氢键能计算，通过和实验数据进行比较，AM1方法给出的优化几何构型、稳定性次序、氢键能和O—H。。。O氢键的0—0距离与实验数据吻合最好，MNDO和MINDO/3方法优化的C-C键长偏长，C-O键和O-H键长偏短；对于C-N键长，MNDO和AM1优化结果差别不大，而MINDO/3给出了过短的C-N键长，MNDO和MINDO/3方法给出的有些水杨酸衍生物分子（如水杨酸甲酯和水杨酰胺）异构体的稳定性次序和实验上推测的可存在异构体结果不一致，MNDO和MINDO/3方法给出的氢键能偏低，对其他体系的研究发现INDO方法常常不能得到质子转移产物的优化几何构型，只能得到反应物的优化构型，并且估算的氢键能偏高，大量的计算结果表明AM1方法对本论文研究的激发态分子内质子转移反应体系是适宜和可靠的。

For such complex and composite systems as analogue and digital systems, electronic and mechanical systems, the Ptolemy II attain purposes with heterogeneously hierarchical ideology, in other words, actors and model of computation at the same level stand for a behavior of the system, and these components at this level can be converted into a composite actor that stands for another behavior of the system under the control of different models of computation at upper level with other actors. In this way, the system may be structured hierarchically.

对于复杂的混合系统，如模拟与数字系统，电子与机械系统，Ptolemy II采用层次异构的思想实现，即同层的角色和计算模型表示系统的一种行为，而这一层组件又可转变为一个复合角色，在上一层与其它角色在不同的计算模型控制下表示系统的另一种行为，从而实现系统的层次构架。

Along with the rapid development of Internet , there are abundant ,isomeric, semi-structured and dynamic information resources on Web. Among these Web information , above 80 percent exist in the form of Web text .

伴随着Internet的飞速发展，Web上出现了海量的、异构的、半结构化的、动态的信息资源，并且在这些Web信息中有80％以上的信息是以Web文本的形式存在的。

Along with the rapid development of Internet,there are abundant ,isomeric,Semi-structured and dynamic information resources on Web. Among these Webinformation,above 80 percent exist in the form of Web text .

伴随着Internet的飞速发展，Web上出现了海量的、异构的、半结构化的、动态的信息资源，并且在这些Web信息中有80%以上的信息是以Web文本的形式存在的。

Web is an information warehouse which is huge, widly distributed, highly isomerous, hyper text and hyper media, while including abundant, dynamic hyperlink and visitorial, usage information to web pages.

Web是一个巨大的、广泛分布的、高度异构的、半结构化的、超文本、超媒体的、相互联系并且不断进化的信息仓库；是一个巨大的文档积累的集合，包括了丰富、动态的超链接信息以及Web页面的访问和使用信息。

Rresults from those studies can be summariazed as follow:(1) A preliminary study no correlationship between the UV-VIS reflection spectrum of tomato fruit surface and the lycopene amount of tomato fruit was undertaken. Based on observation from this study, a damage-free and in-situ detection technique of lycopene amount from tomato was developed with UV-VIS reflection spectroscopy;(2) The geometrical isomers of lycopene were separated successfully on C30-HPLC-PDA-ELSD. The absorption coefficients of Z-isomers were consequently dedermined. The geometrical isomer composition of lycopene could therefore be assessed. Those efforts formed a solid base to identify the natural product from synthetic compound of lycopene;(3) Lycopene resource from the fruit of Autumn oliver was proved to be available for industrial application. An extraction methos of lycopene from the fruit of Autumn oliver by supercritical carbon dioxide was developed at laboratory scale;(4) A method to extract lycopene by supercritical liquid with improved efficiency was developed; Data from this investigation suggested that a proper raw material pre-extraction process was important for a better extraction efficiency;(5) Variation in the geometrical isomer composition of lycopene during its metabolish in rat was assessed. A large amount of Z-isomers were observed. This variation took place in serum;(6) The absorption rate and accumulation in serum of natural lycopene in rat were assessed;(7) Ability to quench singlet oxygen by different geometrical isomers of lycopene was compared;(8) It was detected that whether natural lycopene had functions to regule blood-lipids and LDL antioxidation;(9) A C31 degradation piece of lycopene was found in the prostate gland of rat.

研究结果包括：[1]应用UV-VIS反射光谱法建立了番茄果实中番茄红素含量的无损伤、现场检测技术；[2]应用C30-HPLC-PDA-ELSD技术实现了对番茄红素几何异构体的分离，测定了不同顺式异构体的吸光系数，建立了天然番茄红素几何异构体组成的检测方法，为区分和鉴定人工合成品和天然产物奠定了基础；[3]证实了秋橄榄果实中的番茄红素资源具有工业开发价值，并建立了超临界CO_2萃取的实验室方法；[4]探索了提高番茄红素超临界流体萃取效率的方法，证明了物料前处理对提高萃取效率起了极其重要的作用；[5]观察了番茄红素在大鼠体内几何异构体组成的变化情况，发现了大量顺式异构体的存在，并证实了几何异构体组成在血清中发生了显著变化；[6]测定了天然番茄红素在大鼠体内的吸收率和在大鼠血清中的动态积累规律；[7]比较了不同番茄红素几何异构体淬灭单线态氧的能力；[8]检测了天然番茄红素是否具有调节血脂作用和抗低密度脂蛋白氧化的功能；[9]首次发现大鼠前列腺内存在番茄红素C31降解片段，并证实其仍具有淬灭单线态氧的能力。

Based on the unified data modeling, this resolution realizes the uniform request service to distributed heterogeneous spatial data by metadata and multi-database system.

该解决方案通过建立统一的数据模型，使用元数据与多数据库系统实现了对分布的异构的空间数据的统一访问请求服务。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。