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异戊酸

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They were eucalyptol, bicyclo[2.2.1]heptan-2-one,1,7,7-trimethyl-,(1R)-, borneol, 1-methyl-2-(1-methyl ethenyl)-(1R-cis)-cyclobutaneethanol, limonene, 1-hydroxymethyl-7,7-dimethy lbicyclo[2.2.1]heptan-2-one,-spathulenol, 3,7,11,15-Tetramethyl-2-hexadecen-1-ol, isocitronellol,-9-Octadecenoic acid, heneicosane, respectively.

阿给中共有11个阿给炭没有检测出的成分,包括桉油精、D-樟脑、冰片、(1R-cis)- 1-甲基-2-(1-甲基乙烯基)环丁基乙醇、二戊烯、1-羟甲基-7,7-二甲基-双环[2.2.1]庚-2-酮、-匙叶桉油烯醇、3,7,11,15-四甲基-2-十六碳烯-1-醇、异香茅醇、-9-十八碳烯酸和廿一烷。

The results indicated that Fructose 1,6-bisphosphate aldolase,succinate dehydrogenase ,and hexokinase were very sensitive to temperatures .Citrate-synthase was similar to that of mesophiles in temperature properties .

结果表明Y18细胞中1,6-二磷酸果糖醛缩酶,琥珀酸脱氢酶和己糖激酶对温度很敏感,柠檬酸合成酶的温度效应类似于中温酶,α-酮戊二酸脱氢酶和异柠檬酸脱氢酶存在不同温度特性的同功酶。

Therefore, the metabolic pathway from soybean oil to erythromycin was presumed as follows: soybean oil is metabolized into TCA pathway to generate much α ketoglutaric acid and then generate succinyl CoA by strengthening TCA pathway, and the methylmalonyl CoA is formed from succinyl CoA by isomerization. Finally, methylmalonyl CoA can be used as the precursor for the biosynthesis of erythromycin.

推测豆油经过红色糖多孢菌代谢后进入红霉素合成的一条可能途径:豆油经过代谢后进入TCA循环,并强化了TCA循环的通量,产生了大量α酮戊二酸,再生成琥珀酰CoA,琥珀酰CoA在甲基丙二酰CoA异构酶的作用下生成甲基丙二酰CoA作为红霉素合成的前体。

CoA by strengthening TCA pathway, and the methylmalonyl??CoA is formed from succinyl??CoA by isomerization. Finally, methylmalonyl??CoA can be used as the precursor for the biosynthesis of erythromycin.

餐?戊二酸,再生成琥珀酰CoA,琥珀酰CoA在甲基丙二酰CoA异构酶的作用下生成甲基丙二酰CoA作为红霉素合成的前体。

Synthesis of Antidote of N-Dichloroacetyl-2-methyl-1-oxa-4-aza-spiro-4.4-nonane BI Hong-mei, ZHANG Jin-yan, LIANG Ying, SHEN Yong (College of Arts and Sciences Heilongjiang August First Reclamation University, Daqing 163319, Heilongjiang, China) Abstract: N-Dichloroacetyl-2-methyl-1-oxa-4-aza-spiro-4.4-nonane was synthesized by one pot method with isopropanolamine, cyclopentanone and dichloroacetyl chloride. The optimum reaction conditions obtained are as follows:the proportion in moles of the above materials is 1∶1∶1.2, reaction solvent is toluene, reaction temperature is -15 to -10 ℃,reaction time is 3 h, under the optimum condition, the yield of the compound is 50.0%.

除草剂解毒剂N-二氯乙酰基-2-甲基-1-氧杂-4-氮杂-螺[4.4]壬烷的合成毕洪梅,张金艳,梁英,沈勇(黑龙江八一农垦大学文理学院,黑龙江大庆 163319)摘要:以33%的氢氧化钠水溶液为缚酸剂,异丙醇胺、环戊酮和二氯乙酰氯为原料,采用&一锅法&合成了N-二氯乙酰基-2-甲基-1-氧杂-4-氮杂-螺[4.4]壬烷,采用正交实验法得到最佳反应条件:反应原料摩尔比为1∶1∶1.2,苯作溶剂,反应的温度为-15 ℃~-10 ℃,搅拌时间为3 h,产率达到50.0%。

Trifluoromethyl-3-heptadfluoroisopropyl-2-perfluoropentene-4-(N',N'-dimethylamino propyl) imino was prepared by the reaction of hexafluoropropene timer with N,N-dimethyl propanediamine in the molar ratio 1:1.0 at room temperature for 8h, and the structures of VIII were identified by IR and NMR spectra.

以六氟丙烯三聚体与N,N-二甲基丙二胺为原料合成叔胺2-三氟甲基-3-七氟异丙基-2-全氟戊烯-4-(N',N'-二甲胺丙基)亚胺,利用红外光谱和核磁共振确定其结构,并通过对合成条件的考察得其最佳合成条件:乙醚为溶剂,碳酸钠为缚酸剂,摩尔投料比为1:1.0,在室温下反应8小时。

The p-Isopropylbenzoic acid was synthesized by catalytic transfer dehydrogenation with 5% Pd/C using dihydrocumic acid as material and hydrogen offer, industrial dipentene as hydrogen acceptor and solvent, reacted directly under reflux condition.

采用5% Pd/C作为转移氢催化剂,原料二氢枯茗酸为氢给予剂,以工业双戊烯作为氢接受剂和溶剂,合成了对异丙基苯甲酸。

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