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Limb abnormalities including phocomelia, amelia, clubfeet, polydactyly, microtia, facial palsy, orofacial cleft, microphthalmia, cardiac defect, IUGR, urogenital, gastrointestinal, and spinal defects

四肢异常包括:短肢畸形;无肢畸形;畸形足;多指畸形、小耳畸形;面部麻痹;口面裂;小眼畸形;心脏异常;宫内生长受限;泌尿生殖系的、胃肠道的和记脊柱的缺陷

So far, the cancerogenic mechanism of lung cancer is not well elucidated. Some growth factors and growth factor receptors have been identified to participate in cancerogenic processes, but the downstream pathways regulated by those growth factor receptors are uncleared.

目前已知的癌症发病机理多是生长因子和生长因子的表面受体发生异常所致,因此,进一步阐明受体下游的调控基因对于阐明癌症的发生机理和进一步设计药物靶位点都是十分有意义的。forkhead box P4(FoxP4)就是本文作者在利用生物信息学方法筛选人类心脏发育候选基因的过程中发现的一个人类新基因,目前发现三种转录本。

The aberrant phenotypes were observed in the anther of tobaccotransformed with ZM401 sense construct: the inflorescence growth and floral axiselongation are suppressed; the flower buds falling or flowers abscission earlier wereobserved. The degradation of tapetum are not observed at the binucleate pollen stagewhich corresponds to the mature stage, although the tapetal cells of untransformedtobacco anther at the same stage have already degenerated completely anddisappeared.

对转基因烟草进行形态学、组织学分析结果表明,ZM401基因以反向方式整合的转基因烟草表现一切正常,而含有ZM401正义基因的转基因烟草在表型和组织学上都出现了异常:花序生长缓慢,花序轴变短,生长过程中花逐渐脱落,花序轴褐化枯死;花药绒毡层退化延迟,药室内壁在雄配子体发育后期不能进行带状加厚,阻碍了花粉粒的释放。

The growth growth high peak period that corrected and cured to contribute to make use of a kid in early days stopped excrescent growth growth trend and led to it is as usual.

早期矫治有助于利用孩子的生长发育高峰期阻断异常的生长发育趋势,将其导向正常。

The article focuses on the aberrant expression and significances of proto-oncogenes, tumor suppressor genes and genes associated with the proliferation process of gastric cells such as telomerase, transcription factor and cyclooxygenase, etc. These genes, alone or synergically, participate in gastric cancer cell proliferation, resulting in an uncontrolled growth characterized by over-proliferation of decreased apoptosis of gastric cancer cells.

本文着重阐述了与胃癌细胞增殖过程密切相关的端粒酶、核转录因子、环氧化酶等基因以及参与细胞周期调控的原癌基因、抑癌基因的异常表达及临床意义,这些基因或单独作用,或相互协同,参与胃癌细胞的增殖,使肿瘤细胞生长以增殖过多、凋亡过少的失控性生长为特征。

Recent study indicates abnormal expression and signaling pathway of the TGF-β in uveal melanoma and suggests that abrogation of control of melanocyte growth by the TGF-β may be important in the formation of uveal melanoma.

近年研究TGF-β的异常过表达以及信号传导通路的异常与葡萄膜黑色素瘤生长和侵袭转移能力密切相关。

For thin polycrystalline films, especially those with columnar structure, once the diameter of grains on the film surface is larger than the film thickness, the total area of above and under basal planes (film-substrate interface) will be larger than that of side plane.

对于薄膜特别是柱状晶薄膜,当晶粒在膜平面内的尺寸大于膜厚时,柱状晶粒的上底面和下底面的面积将大于侧面的面积,因此薄膜中的晶粒生长除像整体材料中的晶粒生长一样考虑晶界能外,还需要考虑表面能和界面能,因为各向异性的表面能和界面能将导致薄膜中的异常晶粒生长和织构变化。

For thin polycrystalline films, especially those with columnar structure, once the diameter of grains on the film surface is larger than the film thickness, the total area of above and under basal planes (film-substrate interface) will be larger than that of side plane. Therefore besides the minimization of boundary energy in traditional bulk material, surface energy, interface energy would be considered due to the anisotropy of surface energy, interface energy being able to drive the grain growth and texture evolution in thin films.

对于薄膜特别是柱状晶薄膜,当晶粒在膜平面内的尺寸大于膜厚时,柱状晶粒的上底面和下底面的面积将大于侧面的面积,因此薄膜中的晶粒生长除像整体材料中的晶粒生长一样考虑晶界能外,还需要考虑表面能和界面能,因为各向异性的表面能和界面能将导致薄膜中的异常晶粒生长和织构变化。

"Second, both solid tumors and ascular anomalies (e.g., hemangiomas, port-wine stains) are known to hae increased expression of angiogenic proteins, including ascular endothelial growth factor and basic fibroblast growth factor."

&第二,已知实体瘤和脉管异常(例如血管瘤、葡萄酒色痣)存在血管原的蛋白表达增加,包括血管内皮生长因子和碱性成纤维细胞生长因子。&

It may encode a familiar secretary growth factor protein and play important role in stimulating growth of the cells.

C3orf1基因在高转移肺癌中异常表达,可能是分泌型的生长因子类蛋白,刺激细胞的生长。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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